My vit D and B12 levels are up after supplementing with no obvious improvement in muscle pain. Thyroxine currently at 75mcg after being reduced from 100mcg due to palpitations, insomnia and anxiety symptoms (test results within normal range and GP fobbing me of with anxiety drugs saying symptoms where not thyroid related!! Grr.) - have all improved with the drop in Levo, but the discomfort, stiffness in back, groin and hamstrings, down to back of knees is getting worse. Also having unresolved exhaustion with digestive issues too. No answers from Endo, although may get a trial of T3.