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To those who replied to my question on clinical trials
To those who replied to my question on joining clinical trials, I am overwhelmed by your kindness in sending me emails. I will answer your emails soon but I am currently recovering from a cataract operation and though my eyesight has improved a lot I still have difficulty reading and writing. Bear
To those who replied to my question on joining clinical trials, I am overwhelmed by your kindness in sending me emails. I will answer your emails soon but I am currently recovering from a cataract operation and though my eyesight has improved a lot I still have difficulty reading and writing. Bear
MyMiracle13
in
SHARE Metastatic Breast Cancer
1 year ago
Effect of Melatonin Administration on Mitochondrial Activity and Oxidative Stress Markers in Patients with Parkinson's Disease 2021
Effect of Melatonin Administration on Mitochondrial Activity and Oxidative Stress Markers in Patients with Parkinson's Disease 2021
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8545577/ Abstract Mitochondrial dysfunction and oxidative stress are extensively linked to Parkinson's disease (PD)
Effect of Melatonin Administration on Mitochondrial Activity and Oxidative Stress Markers in Patients with Parkinson's Disease 2021
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8545577/ Abstract Mitochondrial dysfunction and oxidative stress are extensively linked to Parkinson's disease (PD)
Bolt_Upright
in
Cure Parkinson's
1 year ago
IVIG after heart surgery and stopping IBRUTIMIB
12 months ago I was on an Ibrutinib clinical trial for my CLL. Ibrutinib worked great for me for years. I found out I needed a triple bypass due to 95% LAD artery blockage. Not good! A stent wasn’t an option in my case due to necessity for blood thinners. Can’t do blood thinners, aspirin and Irbutinib
12 months ago I was on an Ibrutinib clinical trial for my CLL. Ibrutinib worked great for me for years. I found out I needed a triple bypass due to 95% LAD artery blockage. Not good! A stent wasn’t an option in my case due to necessity for blood thinners. Can’t do blood thinners, aspirin and Irbutinib
misterbee
in
CLL Support
1 year ago
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Volunteer Opportunity - Prostate Cancer Patient Advocate with SWOG for Genitourinary Cancer Committee
I have served as a volunteer Patient Advocate representing the LGBTQ+ Community with the Southwest Oncology Group (SWOG) for the past two years. As such I am serving as a member of the Patient Advocacy Committee (PAC) and the Diversity, Equality, and Inclusion Committee. I attend monthly zoom meetings
I have served as a volunteer Patient Advocate representing the LGBTQ+ Community with the Southwest Oncology Group (SWOG) for the past two years. As such I am serving as a member of the Patient Advocacy Committee (PAC) and the Diversity, Equality, and Inclusion Committee. I attend monthly zoom meetings
JRPnSD
in
Advanced Prostate Cancer
1 year ago
HAS ANYONE PARTICIPATED IN CLINICAL TRIALS
Hello everyone. Has anybody on this forum ever joined in a clinical trial? I have been invited to join a Phase 1 clinical trial for LOXO-783. The new drug is for those who have the PIK3CA mutation. At first I was very excited to join but when I was looking at the screening requirements, I don’t
Hello everyone. Has anybody on this forum ever joined in a clinical trial? I have been invited to join a Phase 1 clinical trial for LOXO-783. The new drug is for those who have the PIK3CA mutation. At first I was very excited to join but when I was looking at the screening requirements, I don’t
MyMiracle13
in
SHARE Metastatic Breast Cancer
1 year ago
response to clinical trial application?
A couple of months ago, I applied for a clinical trial that had just started recruiting. They are still recruiting and have begun administering the trial drug to participants. I never heard from trial staff. Has anyone applied for a trial and received notice whether they were rejected? Thank you. Sashay
A couple of months ago, I applied for a clinical trial that had just started recruiting. They are still recruiting and have begun administering the trial drug to participants. I never heard from trial staff. Has anyone applied for a trial and received notice whether they were rejected? Thank you. Sashay
Sashay2020
in
My Ovacome
1 year ago
Interesting video with active ongoing clinical trial. Maybe on option for some!!
https://www.urotoday.com/video-lectures/asco-2022/video/2853-the-future-of-radiopharmaceuticals-in-the-treatment-of-prostate-cancer-philip-kantoff.html
https://www.urotoday.com/video-lectures/asco-2022/video/2853-the-future-of-radiopharmaceuticals-in-the-treatment-of-prostate-cancer-philip-kantoff.html
Bkraus1
in
Advanced Prostate Cancer
1 year ago
More on the biomarker NFL
The identification of disease-modifying therapies is the Holy Grail of PD research, but to date no drug has been approved as such a therapy.1 There are numerous disease-modifying therapies currently in the pipeline attempting to modify the underlying pathomechanisms. In recent years, the results of
The identification of disease-modifying therapies is the Holy Grail of PD research, but to date no drug has been approved as such a therapy.1 There are numerous disease-modifying therapies currently in the pipeline attempting to modify the underlying pathomechanisms. In recent years, the results of
House2
in
Cure Parkinson's
1 year ago
Annovis Bio Announces Approval for EU Clinical Trial Sites for the Phase 3 Study of Buntanetap for the Treatment of Parkinson's Disease
This trial is already open in the United States, and I believe some on this forum are participating. This announcemment indicates that the company is also opening clinical trial sites across the EU. I checked clnicaltrials.gov but they have not listed the EU sites yet. https://www.prnewswire.com/news-releases
This trial is already open in the United States, and I believe some on this forum are participating. This announcemment indicates that the company is also opening clinical trial sites across the EU. I checked clnicaltrials.gov but they have not listed the EU sites yet. https://www.prnewswire.com/news-releases
Canddy
in
Cure Parkinson's
1 year ago
Neuron23 Announces First-in-Human Dose in Phase 1 Clinical Trial of its Best-in-Class Brain-Penetrant LRRK2 Inhibitor for Parkinsons Disease
NEU-723 has been shown in preclinical studies to have strong disease-modifying potential with a higher therapeutic index than other candidates in development https://www.prnewswire.com/news-releases/neuron23-announces-first-in-human-dose-in-phase-1-clinical-trial-of-its-best-in-class-brain-penetrant-lrrk2
NEU-723 has been shown in preclinical studies to have strong disease-modifying potential with a higher therapeutic index than other candidates in development https://www.prnewswire.com/news-releases/neuron23-announces-first-in-human-dose-in-phase-1-clinical-trial-of-its-best-in-class-brain-penetrant-lrrk2
Farooqji
in
Cure Parkinson's
1 year ago
Athira announces clinical trials for Alzheimer’s, Parkinson’s, ALS treatments in 2023
https://www.healio.com/news/neurology/20230207/athira-announces-clinical-trials-for-alzheimers-parkinsons-als-treatments-in-2023
https://www.healio.com/news/neurology/20230207/athira-announces-clinical-trials-for-alzheimers-parkinsons-als-treatments-in-2023
Farooqji
in
Cure Parkinson's
1 year ago
📚 Research 101: Understanding the phases of a clinical trial
Clinical trials are conducted in phases. The trials at each phase have a different purpose and help scientists answer different questions: In the pre-clinical phase, researchers determine in a treatment or drug is safe and useful within a lab environment. In Phase I trials, researchers test a new
Clinical trials are conducted in phases. The trials at each phase have a different purpose and help scientists answer different questions: In the pre-clinical phase, researchers determine in a treatment or drug is safe and useful within a lab environment. In Phase I trials, researchers test a new
AnnaHU
HealthUnlocked
in
Research Opportunities
1 year ago
Besremi dosing research
It shows Besremi works better in 250-350-500 mcg in a month. [The response outcomes observed in multiple clinical trials of ropeginterferon alfa-2b confirm clinical benefits in MPN patients. Emerging data utilizing the 250-350-500 mcg regimen suggest that a higher initial dose with faster dose titration
It shows Besremi works better in 250-350-500 mcg in a month. [The response outcomes observed in multiple clinical trials of ropeginterferon alfa-2b confirm clinical benefits in MPN patients. Emerging data utilizing the 250-350-500 mcg regimen suggest that a higher initial dose with faster dose titration
Wennn
in
MPN Voice
1 year ago
LLS.ORG (USA) WHAT ARE YOUR TOP PRIORITIES FOR 2023?
Dear Advocate, Whether it’s making sure every patient can afford health insurance that works for them or advancing better treatments, LLS is committed to working tirelessly to advance policies that serve the needs of blood cancer patients and their families. In 2023 we will continue to work closely
Dear Advocate, Whether it’s making sure every patient can afford health insurance that works for them or advancing better treatments, LLS is committed to working tirelessly to advance policies that serve the needs of blood cancer patients and their families. In 2023 we will continue to work closely
lankisterguy
Volunteer
in
CLL Support
1 year ago
PharmaTher Submits FDA Meeting Package to Discuss Phase 3 Program and Fast Track Designation for KETARX™ (Ketamine) in PD
https://www.benzinga.com/pressreleases/23/02/g30671310/pharmather-holdings-submits-fda-meeting-package-to-discuss-phase-3-program-and-fast-track-designat?utm_source=dlvr.it&utm_medium=twitter TORONTO, Feb. 01, 2023 (GLOBE NEWSWIRE) -- PharmaTher Holdings Ltd. (the "Company" or "PharmaTher") PHRRF
https://www.benzinga.com/pressreleases/23/02/g30671310/pharmather-holdings-submits-fda-meeting-package-to-discuss-phase-3-program-and-fast-track-designat?utm_source=dlvr.it&utm_medium=twitter TORONTO, Feb. 01, 2023 (GLOBE NEWSWIRE) -- PharmaTher Holdings Ltd. (the "Company" or "PharmaTher") PHRRF
Hidden
in
Cure Parkinson's
1 year ago
MANF Stack Rationale
….FOR INFORMATIONAL PURPOSES ONLY…… Unconventional neurotrophic factor MANF targets midbrain structures, including the Substantia Nigra, through endoplasmic reticulum mediated mechanisms. The midbrain, also called the mesencephalon, region of the brain serves important functions in motor activity
….FOR INFORMATIONAL PURPOSES ONLY…… Unconventional neurotrophic factor MANF targets midbrain structures, including the Substantia Nigra, through endoplasmic reticulum mediated mechanisms. The midbrain, also called the mesencephalon, region of the brain serves important functions in motor activity
House2
in
Cure Parkinson's
1 year ago
CLL Treatment concerns
Hello all, I have different options for my treatment, I have a lot of enlarged lymph nodes in my abdomen as per cat scan, it is causing me a lot of discomfort . I am 57 yrs old and my CLL is progressing. I need a treatment that can work getting my Lymph nodes back to normal size. I had a 6 months
Hello all, I have different options for my treatment, I have a lot of enlarged lymph nodes in my abdomen as per cat scan, it is causing me a lot of discomfort . I am 57 yrs old and my CLL is progressing. I need a treatment that can work getting my Lymph nodes back to normal size. I had a 6 months
CA28
in
CLL Support
1 year ago
Lymphatic Dysfunction Found to Play Big Role in SLE Photosensitivity
Poor drainage in lymphatic system might explain processes leading to lupus flares by Lindsey Shapiro Reduced lymphatic drainage might explain why skin reactions to sunlight, or photosensitivity, may lead to systemic immune reactions and overall disease flareups in people with systemic lupus erythematosis
Poor drainage in lymphatic system might explain processes leading to lupus flares by Lindsey Shapiro Reduced lymphatic drainage might explain why skin reactions to sunlight, or photosensitivity, may lead to systemic immune reactions and overall disease flareups in people with systemic lupus erythematosis
lupus-support1
Administrator
in
LUpus Patients Understanding and Support
1 year ago
📚 Research 101: What is a Clinical Trial
[u]
What is a clinical trial?
[/u] A clinical trial is a research study that determines whether new treatments are safe and effective for humans. Clinical trials are strictly controlled to ensure the safety of the people taking part. [u]
Who comes up with clinical trials?
[/u] Ideas for
[u]
What is a clinical trial?
[/u] A clinical trial is a research study that determines whether new treatments are safe and effective for humans. Clinical trials are strictly controlled to ensure the safety of the people taking part. [u]
Who comes up with clinical trials?
[/u] Ideas for
AnnaHU
HealthUnlocked
in
Research Opportunities
1 year ago
Phase 1b trial shows reformulated Niclosamide has promise for CRPC
Niclosamide in prostate cancer: An inhibitor of AR-V7, a mitochondrial uncoupler, or more? Author links open overlay panelMinasSakellakisabShow moreOutlineShareCite https://doi.org/10.1016/j.ctarc.2023.100685 Get rights and contentUnder a Creative Commons licenseOpen accessHighlights •A recent phase
Niclosamide in prostate cancer: An inhibitor of AR-V7, a mitochondrial uncoupler, or more? Author links open overlay panelMinasSakellakisabShow moreOutlineShareCite https://doi.org/10.1016/j.ctarc.2023.100685 Get rights and contentUnder a Creative Commons licenseOpen accessHighlights •A recent phase
Graham49
in
Advanced Prostate Cancer
1 year ago
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