Besremi dosing research

[Wennn]

It shows Besremi works better in 250-350-500 mcg in a month.

[The response outcomes observed in multiple clinical trials of ropeginterferon alfa-2b confirm clinical benefits in MPN patients. Emerging data utilizing the 250-350-500 mcg regimen suggest that a higher initial dose with faster dose titration may lead to earlier complete hematological remission. Although a direct comparison is not possible in the absence of head-to-head data, treatment with this regimen in PV for 6 months led to CHR rates comparable to those observed at 12 months in the studies utilizing the low starting dose and slower titration schema.]

frontiersin.org/articles/10...

[saltmarsh]

Thanks for providing that update. Besremi probably in my future and I appreciate all the info I can find. Saltmarsh

[GardNerd]

Thanks for posting this!

[Meatloaf9]

Thank you for posting the link to this article, good information. Best to you.

[Ovidess]

I sent this on to my oncologist. I'm hoping he'll discuss it with his colleagues. (None of whom are MPN specialists--I'm in a smaller city.)

[mfh7]

Thanks for providing this. Since my Besremi dosage is now at 500 mcgs after a year I found this article reassuring as I note many patents are at a much lower dose. Although the rate at which my hct increases due to Besremi has slowed I am still requiring phlebotomy once every three months which is why my doc has slowly increased the dosage over a year. I have been at 500 mcgs for two months and am curious to see my labs this month to see if we are getting better hct control from the higher dose.

[Wennn in reply to mfh7]

Please keep us updated about your progress. It may help more people. Best luck.👍