Annovis Bio Announces Approval for EU Clinical Trial Sites for the Phase 3 Study of Buntanetap for the Treatment of Parkinson's Disease

[Canddy]

This trial is already open in the United States, and I believe some on this forum are participating. This announcemment indicates that the company is also opening clinical trial sites across the EU. I checked clnicaltrials.gov but they have not listed the EU sites yet.

prnewswire.com/news-release...

clinicaltrials.gov/ct2/show...

I am cautiously optimistic about this trial because they had positive statistically significant results in Phase 2 with this drug for Parkinson's Disease and this is a large Phase 3 trial that is moving fast. The company is planning an interim analysis in Quarter 2 of this year (2023) to assess whether the number of subjects planned to enroll is adequate. We should have some answers (i.e., does it work in a clinically meaningful way and is it safe) about this drug around the end of 2024/beginning of 2025.

[1953bullard]

got my first months supply today!

[rancsikanna in reply to 1953bullard]

Super. Later in, can you share with us your experience?

[1953bullard in reply to rancsikanna]

will do!

[LauraYu in reply to 1953bullard]

👍👍👍wish you good luck!

[1953bullard in reply to LauraYu]

thank you!

[rancsikanna in reply to 1953bullard]

Hi! Good news that they continue the trial here in Hungary and my husband willing to participate. During thr trial do you have to stop other medications? I mean levedopa.If youbget placebo... do they provide you with meds after finishing the trial?

[1953bullard in reply to rancsikanna]

you continue all current meds while in the trial and after the trial is over everyone has opportunity to take the drug for one year at no cost

[rancsikanna in reply to 1953bullard]

Thank you. And in the meantime you also kept the dosage of your current med right?

[1953bullard in reply to rancsikanna]

correct, you aren’t supposed to change anything you are currently taking

[jeffreyn]

See also this recent PNT article:

parkinsonsnewstoday.com/new...

[rancsikanna]

I promiss it is my last queation😀 and do you know what kind of motor symptoms does it likely to improve