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CLINICAL TRIALS RE MANITOL
Is anyone aware of any clinical trials involving manitol?
Is anyone aware of any clinical trials involving manitol?
SonarsMom
in
Cure Parkinson's
3 years ago
Newly approved drug effective against lung cancer caused by genetic mutation
The new drug sotorasib reduces tumor size and shows promise in improving survival among patients with lung tumors caused by a specific DNA mutation, according to results of a global phase 2 clinical trial. The drug is designed to shut down the effects of the mutation, which is found in about 13% of patients
The new drug sotorasib reduces tumor size and shows promise in improving survival among patients with lung tumors caused by a specific DNA mutation, according to results of a global phase 2 clinical trial. The drug is designed to shut down the effects of the mutation, which is found in about 13% of patients
2greys
in
Lung Conditions Community Forum
3 years ago
Positive Effects of HIIT Exercise program on BCR progression of PC
From the ASCO2021 programs. Good randomized trial of supervised intensive exercise for 12 weeks improves risks for BCR progression. I suspect this may be related to the effects of exercise, and especially HIIT to activate epigenetic pathways for protection of the genome and reducing mutations, a driver
From the ASCO2021 programs. Good randomized trial of supervised intensive exercise for 12 weeks improves risks for BCR progression. I suspect this may be related to the effects of exercise, and especially HIIT to activate epigenetic pathways for protection of the genome and reducing mutations, a driver
MateoBeach
in
Advanced Prostate Cancer
3 years ago
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Inflammatory Pathophysiology as a Contributor to MPN
« Clinical evidence that JAK2 inhibition by ruxolitinib in MF neither reliably reduces malignant clonal burden nor eliminates cytokine elevations, suggests targeting cytokine mediated signaling as a therapeutic strategy, which is being pursued in new clinical trials » « The clearly prominent role of
« Clinical evidence that JAK2 inhibition by ruxolitinib in MF neither reliably reduces malignant clonal burden nor eliminates cytokine elevations, suggests targeting cytokine mediated signaling as a therapeutic strategy, which is being pursued in new clinical trials » « The clearly prominent role of
Manouche
in
MPN Voice
3 years ago
new-radiation-therapy
https://www.nbcnews.com/health/mens-health/new-radiation-therapy-prostate-cancer-reduces-deaths-study-shows-n1269566 that level of improvement. June 3, 2021, 5:21 PM EDT By Linda Carroll By the time Michael Rosenblum’s prostate cancer was discovered, it was already at a late stage. He’d initially
https://www.nbcnews.com/health/mens-health/new-radiation-therapy-prostate-cancer-reduces-deaths-study-shows-n1269566 that level of improvement. June 3, 2021, 5:21 PM EDT By Linda Carroll By the time Michael Rosenblum’s prostate cancer was discovered, it was already at a late stage. He’d initially
PeteLG
in
Advanced Prostate Cancer
3 years ago
I've written about 80 pages of a prostate cancer book. It is primarily focused on non-SOC, but govt researched methods.
This is my take on some drugs and supplements. I'm sure that there are others that I will add or delete as time goes on (I'm working my way through clinical trials, PubMed, examine, and some other sources). I've been following some of this from shortly after diagnosis. And all of it for a couple of months
This is my take on some drugs and supplements. I'm sure that there are others that I will add or delete as time goes on (I'm working my way through clinical trials, PubMed, examine, and some other sources). I've been following some of this from shortly after diagnosis. And all of it for a couple of months
Hidden
in
Advanced Prostate Cancer
3 years ago
Two new drug approvals (for patients with EGFR Exon 20 insertion and patients with KRAS G12C mutation)
Hi everyone, I know Denzie posted about at least one of the new drug approvals fbut I figured it can't hurt to post about the new approvals again so people are aware of them. With both approvals, I wanted to share why it's important to know what your biomarker test results. Sometimes healthcare professionals
Hi everyone, I know Denzie posted about at least one of the new drug approvals fbut I figured it can't hurt to post about the new approvals again so people are aware of them. With both approvals, I wanted to share why it's important to know what your biomarker test results. Sometimes healthcare professionals
Miranda_GO2
Administrator
in
Lung Cancer Support
3 years ago
Leukemia & Lymphoma Society COVID-19 vaccine safety data is now available ; vaccine antibody data expected later in 2021
On behalf of the Leukemia & Lymphoma Society, thank you again for joining the LLS National Patient Registry, a project of the Michael J. Garil Patient Data Collective, and a special thanks to those of you who are participating in our COVID-19 study. This study is giving us unique information and insights
On behalf of the Leukemia & Lymphoma Society, thank you again for joining the LLS National Patient Registry, a project of the Michael J. Garil Patient Data Collective, and a special thanks to those of you who are participating in our COVID-19 study. This study is giving us unique information and insights
lankisterguy
Volunteer
in
CLL Support
3 years ago
Radical Prostatectomy vs External Beam Radiation Therapy for High-Grade, Clinically Localized Prostate Cancer
TAKE-HOME MESSAGE This retrospective study sought to emulate a randomized trial comparing outcomes between prostatectomy and radiation therapy for high-grade (Gleason score 8–10), clinically localized prostate cancer. The data were extracted from the National Cancer Database (2006–2015) and propensity
TAKE-HOME MESSAGE This retrospective study sought to emulate a randomized trial comparing outcomes between prostatectomy and radiation therapy for high-grade (Gleason score 8–10), clinically localized prostate cancer. The data were extracted from the National Cancer Database (2006–2015) and propensity
Balsam01
in
Advanced Prostate Cancer
3 years ago
OxPLoreD clinical trial for those with high count MBL or early stage CLL --More recruits needed
As Milla15 wrote 6 months ago "this trial which is currently recruiting for high count Monoclonal B-cell Lymphocytosis or very early stage CLL patients (as well as a couple of other early stage blood disorders of uncertain significance). Trial will last 5 years and aims to discover markers which can
As Milla15 wrote 6 months ago "this trial which is currently recruiting for high count Monoclonal B-cell Lymphocytosis or very early stage CLL patients (as well as a couple of other early stage blood disorders of uncertain significance). Trial will last 5 years and aims to discover markers which can
JEEA
in
CLL Support
3 years ago
Antibiotics no help for mysterious lung-scarring disease, large trial finds.
Doctors have hoped that antibiotics could benefit patients with chronic lung diseases, but a new study has found no benefit for patients with life-threatening idiopathic pulmonary fibrosis in preventing hospitalization or death. While there were no statistical benefits for patients with the lung-scarring
Doctors have hoped that antibiotics could benefit patients with chronic lung diseases, but a new study has found no benefit for patients with life-threatening idiopathic pulmonary fibrosis in preventing hospitalization or death. While there were no statistical benefits for patients with the lung-scarring
2greys
in
Lung Conditions Community Forum
3 years ago
NIH launches clinical trial of universal influenza vaccine candidate.
A first-in-human, Phase 1 trial assessing the safety and immunogenicity of an investigational nanoparticle influenza vaccine designed to provide long-lasting protection against multiple flu virus strains has begun at the National Institutes of Health Clinical Center in Bethesda, Maryland. Healthy participants
A first-in-human, Phase 1 trial assessing the safety and immunogenicity of an investigational nanoparticle influenza vaccine designed to provide long-lasting protection against multiple flu virus strains has begun at the National Institutes of Health Clinical Center in Bethesda, Maryland. Healthy participants
2greys
in
Lung Conditions Community Forum
3 years ago
Cancer Research Institute: how immunotherapy is reshaping patient survivorship experiences
Folks may have interest in attending this free webinar: https://us02web.zoom.us/webinar/register/2616175824493/WN_Otx1kNN0SgSg-LAxTeyRuA?fbclid=IwAR06sNPGyyMdRp9yjPaiAJg33ne9n8XjGdSR_cbQy4HaRbpe7GIMTXGN9Eg How Immunotherapy is Reshaping Cancer Patient Survivorship Experiences Description Breakthroughs
Folks may have interest in attending this free webinar: https://us02web.zoom.us/webinar/register/2616175824493/WN_Otx1kNN0SgSg-LAxTeyRuA?fbclid=IwAR06sNPGyyMdRp9yjPaiAJg33ne9n8XjGdSR_cbQy4HaRbpe7GIMTXGN9Eg How Immunotherapy is Reshaping Cancer Patient Survivorship Experiences Description Breakthroughs
missyrand
Ambassador
in
Melanoma Caregivers
3 years ago
Annovis Bio - more positive news from PD, AD clinical trial . . .
Small trial but additional encouraging news for PD and AD communities . . . https://irpages2.eqs.com/websites/annovis/English/431010/us-press-release.html?airportNewsID=b6b5cfe1-123f-45fa-9ab2-fd42c8960048
Small trial but additional encouraging news for PD and AD communities . . . https://irpages2.eqs.com/websites/annovis/English/431010/us-press-release.html?airportNewsID=b6b5cfe1-123f-45fa-9ab2-fd42c8960048
redhawk1
in
Cure Parkinson's
3 years ago
CLL Research: Phase 2 CAPTIVATE Study Suggests Role for Fixed-Duration Treatment of CLL/SLL
https://cllpharmacist.com/cll-research-phase-2-captivate-study-suggests-role-for-fixed-duration-treatment-of-cll-sll/ The data in the uMRD cohort of this trial suggest that fixed-duration therapy is feasible in patients who achieve undetectable MRD (uMRD) status. The selection of durations for these
https://cllpharmacist.com/cll-research-phase-2-captivate-study-suggests-role-for-fixed-duration-treatment-of-cll-sll/ The data in the uMRD cohort of this trial suggest that fixed-duration therapy is feasible in patients who achieve undetectable MRD (uMRD) status. The selection of durations for these
WinJ3
in
CLL Support
3 years ago
Zhittya Genesis Medicine's Drug Reverses Aggregated Synuclein Accumulation in an Animal Model of Parkinson's Disease
I posted earlier on preclinical findings that our growth factor drug (human FGF-1) can regenerate new dopamine-secreting neurons in a primate model of PD. This led to a significant improvement in motor skill functioning of the monkeys. I would now like to share data with you that FGF-1 can also decrease
I posted earlier on preclinical findings that our growth factor drug (human FGF-1) can regenerate new dopamine-secreting neurons in a primate model of PD. This led to a significant improvement in motor skill functioning of the monkeys. I would now like to share data with you that FGF-1 can also decrease
j2jacobs
in
Cure Parkinson's
3 years ago
Exenatide PD3 - Latest info
The protocol of the ‘Exenatide-PD3’ study has been published - An ongoing multicentre, double blind, parallel group, placebo controlled, Phase 3 clinical trial is assessing once weekly Bydureon treatment in Parkinsons over 2yrs https://bmjopen.bmj.com/content/11/5/e047993
The protocol of the ‘Exenatide-PD3’ study has been published - An ongoing multicentre, double blind, parallel group, placebo controlled, Phase 3 clinical trial is assessing once weekly Bydureon treatment in Parkinsons over 2yrs https://bmjopen.bmj.com/content/11/5/e047993
Farooqji
in
Cure Parkinson's
3 years ago
CLL 17p - Rituximab/Imbruvica then Rituximab/Venetoclax or enter in a clinical trial ?
First of all I would like to thank you for responding to my previous post... It really helps me ! My mom had an appointment last Thursday 27th in another hospital to see if she could be included in the following clinical trial: "A phase 3 multicentre, randomized, prospective, open-label trial of ibrutinib
First of all I would like to thank you for responding to my previous post... It really helps me ! My mom had an appointment last Thursday 27th in another hospital to see if she could be included in the following clinical trial: "A phase 3 multicentre, randomized, prospective, open-label trial of ibrutinib
Noham027
in
CLL Support
3 years ago
New Mitochondrial enzyme target, and a chance for Oligometastatic patients to step up--MetaCure trial-some information
Salutations FPC members, First, a look at a new mitochondrial enzyme target for those failing treatment. The process of ferroptosis can lead to cancer cell death and inhibit tumor growth, but a mitochondrial enzyme (DHODH) can block that process. Researchers have found that using brequinar, a drug being
Salutations FPC members, First, a look at a new mitochondrial enzyme target for those failing treatment. The process of ferroptosis can lead to cancer cell death and inhibit tumor growth, but a mitochondrial enzyme (DHODH) can block that process. Researchers have found that using brequinar, a drug being
NPfisherman
in
Fight Prostate Cancer
3 years ago
Radical prostatectomy & metastatic PCa.
New study below [1]. "Newly diagnosed metastatic prostate cancer patients with M1a/b substages, treated with radical prostatectomy or external beam radiation therapy were abstracted from the Surveillance, Epidemiology and End Results database (2004-2016)." "Of 4280 patients, 954 (22.3%) were treated
New study below [1]. "Newly diagnosed metastatic prostate cancer patients with M1a/b substages, treated with radical prostatectomy or external beam radiation therapy were abstracted from the Surveillance, Epidemiology and End Results database (2004-2016)." "Of 4280 patients, 954 (22.3%) were treated
pjoshea13
in
Advanced Prostate Cancer
3 years ago
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