Experiences with

Tamsulosin / Dutasteride

I've only taken 02 pills of dutasteride + tamsulosin hydrochloride, and already no sperm during orgasm. Pretty fast, right? I'm very worried about the side effects of this medication and how long I need to take it. And the consequences... Can anyone enlighten me, please?

I thought this tidbit was interesting. Illustrates a pitfall in generalizing from a rat study to humans. Petri dish studies are even worse. The half-life of dutasteride is approximately 5 weeks in humans, requiring 5-6 months for a complete washout. In rats, dutasteride has a much shorter half-life

Strategies to Resensitize CRPC to AR-Targeted Therapies Castration-resistant prostate cancer (CRPC) often remains driven by the androgen receptor (AR) pathway despite resistance to standard AR-targeted treatments. Numerous strategies – from drugs and combinations to hormonal cycling and lifestyle changes

I'm testing this to verify but it appears that using Zytiga within 4-5 weeks of SPA is a big no-no. Zytiga's first metabolite is Δ4-Abiraterone. It inhibits 5-ar. So, inhibits T->DHT. Should be simple to test. I'll have the first half of the results this week. N of 1 but I'm the 1 so good on me :) If

I don’t know what the risk/reward ratio is but something that a person at high risk of PCa might consider. When my kids get a little older I’m going to talk to them about this. We have lots of data. This is just one clinical trial. Prevention of PCa using dutasteride. https://clinicaltrials.gov

Trihexyphenidyl (Artane)Chemotherapy and hormonal medicines: Antiandrogens (Casodex, Flutamide, Nilutamide) Busulfan (Myleran) Cyclophosphamide (Cytoxan) Ketoconazole LHRH agonists (Lupron, Zoladex) LHRH antagonist (Firmagon) Other medicines: Aminocaproic acid (Amicar) Atropine Clofibrate (Atromid-S

I have always been told that Tamsulosin will not significantly effect PSA values like 5-alpha reductase inhibitors do, such as Avodart and Proscar. The reason for this is because the 5-alpha reductase inhibitors reduce the prostate size, while alpha blocks relax the muscles in the prostate and bladder

I've been taking Flowmax for several months, along with my Orgovyx, because of some hesitancy and feeling like not emptying my bladder fully. Not sure if it's doing anything about that. I go through periods of normalcy, followed by times where I have to pee often. I'm thinking about stopping it, at

Has anyone taken Dutasteride? Also called Avodart? It’s to shrink the swelling of your prostate. I just want to know if it’ll make you not be able to get an erection and an orgasm? It say not to take cialis with it. Why not?

Has anyone used Bicalutamide & Dutasteride for keeping localized PCa stable during AS?

hi, i was diagnosed with bph early 2024 after going into retention. before I started taking tamsulosin I found it very difficult to pass urine. On three occasions I strained to the point of passing out just to get a drop of urine out. I’ve since been diagnosed with heart disease. I’m convinced excessive

I was diagnosed with Gleason 8 prostate cancer in 2022. I have prostap hormone injections every 3 months. I was put on Tamsulosin/Flomax 8 months ago - I had no problem with peeing before going on it but after coming off it because of side effects, for the last 2 months I have had increased urgency,

Hi! I'm in my 60's. In 09/2024, I had nephroureterectomy surgery to remove left kidney & ureter due to grade 3 cancer. Before surgery I was already on 5mg ramipril and 20mg atorvastatin. Now BP has gone higher as expected with single kidney. GP has added amlodipine 10mg to the ramipril, and now I'm suffering

I had my bladder scan several weeks ago, prostate was 39cc down from 45cc, I assume this is down to the Tamsulosin. Anyway, I’ve been diagnosed with mitral regurgitation so have been doing some on the floor exercising such as sit ups for the past week or so. Over the past 2 days I’ve noticed I’m waiting

Tamsulosin user 3yrs... and despite some online opinions it definitely DOESN'T stop ED... I'm a healthy fit 61yr old... with normal healthy attitude to sex...but have struggled to feel anything like hardness since using this drug..also semen production is less than a third volume now too. Heard alpha

If you are diagnosed with urine retention due to a large prostate prior to taking Tamsulosin, from our experience it would be worth asking for repeat flow tests to check if it is working - ask when - perhaps start after 2 or 3 weeks). If this applies to you do read on! - lengthy post! My husband was

Hello, I've recently been prescribed Tamsulosin for an enlarged prostate (BPH I am assuming, until told otherwise) following a couple of UTIs that floored me and frequency of urination/ low pressure. I've got them but haven't taken them yet as I'm a little bothered about the potential side effects.

I just wanted to share this as sometimes it feels like I’m alone or maybe some people can relate to this but anyway I just thought I’d share my experience. I’m 41. I started developing BPH symptoms towards the middle end of 2022 when I noticed I was struggling to empty my bladder before bed. After

has anyone encountered side effects from tamsulosin? I’ve been taking it for around 2-3 months and just been told I have a heart murmur.

I was recently prescribed Tamsulosin for Prostate problems. After a couple of weeks I had to have my regular INR blood test for my Warfarin levels. After taking Warfarin for nearly 20 years with all readings within the therapeutic range of 2- 2.5 my results showed a reading out of range at 3.3.