Tamsulosin - urine retention - a caut... - Advanced Prostate...

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Tamsulosin - urine retention - a cautionary tale

Kalecrew profile image
4 Replies

If you are diagnosed with urine retention due to a large prostate prior to taking Tamsulosin, from our experience it would be worth asking for repeat flow tests to check if it is working - ask when - perhaps start after 2 or 3 weeks).

If this applies to you do read on! - lengthy post!

My husband was suffering from urine frequency which led to his Prostate Cancer diagnosis.

Following a urinary flow test which showed some retention, he was told by the urologist that he could 'try Tamsulosin', as an alternative to a catheter. Neither was explained in any detail as to risks and benefits.

He chose to try the Tamsulosin and soon began to suffer increasing incontinence - copious at night, and also constipation for which laxido was prescribed. His stomach felt a bit hard which he put down to the constipation and he then got an umbilical hernia so he went to his GP who felt his abdomen and sent him straight to A&E. (4 hours wait -too busy - return next day -long wait- chaotic hellhole experience) He eventually got admitted to a well run ward where he received very good attention. He'd been taking Tamsulosin for several weeks and had seen and spoken to drs and nurses about the incontinence and was advised to keep going with the Tamsulosin.

The urologist there quickly diagnosed serious urine retention which was a surprise to us given the amount of urine he had been passing.

This urologist then told him that 'Tamsulosin would not work for his size prostate' (size determined from previous scans and reports by the first urologist)

This urine retention had caused a severe decline to egfr 25 - down from > 90 in his kidney function test taken only a few weeks previous taking Tamsulosin.

Had he not seen the GP about the hernia it would have become even worse.

He then was given drips and had to have the bladder drained with the decompression risks that brings.

After discharge he needed to use a urinary catheter until his successful Green Light Laser surgery for the enlarged prostate.

After having a catheter the TURP or Laser treatment has to be done within a few months - it was left until the time was running out.

In retrospect it would have been worth paying to get it done sooner.It may be worth finding out if an op is an option to Tamsulosin sooner rather than later, as no drugs are required once it's done though many are happy with the drug.

We had to choose between the TURP and the Laser and received little guidance until we persuaded our new urologist to tell us which would he choose - he said the green laser - usually a day procedure with quicker recovery.

(We had the new urologist because we felt that the one we had first should likely have been aware that Tamsulosin might not work among other reasons).

Our new one, who also performed the op is a good communicator with a very pleasant manner and keeps an eye on my husband with regular checks although now he is under an oncologist as well.

The kidney function improved though not back to previous levels.

we believe that this whole sorry saga would have been avoided if the first urologist, who said my husband could 'try Tamsulosin', had arranged for my husband to come back and test to find out if it's working.

Sorry about the lengthy post - I just hope it might help someone somewhere avoid this overall traumatic experience by being aware of the risks and symptoms of urine retention.

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Kalecrew
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Daveofnj profile image
Daveofnj

How large was his prostate when the doctor said Tamsulosin would not work?

Kalecrew profile image
Kalecrew in reply toDaveofnj

firstly apologies to those who liked my post and then after I edited some grammar they may have lost track of the post

Good question Daveofnj thanks - just dug through the fat file of tests and papers and found that my husband's prostate volume was 55cc

sometimes they measure in ml (cc = ml. Although 1cc or 1 ml of water equals1g , this will not apply to the prostate due to the different weights of tissues. eg 1 ml of milk weighs more than 1 ml of water. I'm adding this because google throws up 1g=1cc=1g and it would be easy to misinterpret the weight of the prostate)

55cc doesn't appear to be in the largest category as they can apparently be up to 120ml. 30ml is the higher end of normal

I'm not exactly sure why the hospital urologist stated that "tamsulosin wouldn't work for his size prostate" and didn't question him at the time. He attended us in the acute surgical ward. However, thanks to your question, I have found that a stronger drug such as a 5-alpha reductase inhibitor is prescribed for those with a high volume prostate, and is more effective than an alpha reductase inhibitor such as tamsulosin, so perhaps that is what the hospital doctor was thinking.

I did just find a paper, below but this paper appears to be a poor translation and has errors - such as here as surely they mean 40g not 40mg!

the paper warns that, "Tamsulosin monotherapy may not be enough for large prostate (>40 mg) to maintain adequate symptom relief, and it is better to start with other medical options such as combined therapy or early nonmedical therapy" and they detail other options

pmc.ncbi.nlm.nih.gov/articl...

(such studies may exclude those with PCa)

My husband's was found to have significant calcification during the green light laser op, and holmium laser was used in addition to the green light laser. Apparently calicification or stones is common and we were told that the cause is not known. Some research suggests bacteria may be involved - must put this to the community!

SteveTheJ profile image
SteveTheJ

I did not read your entire post but keep in mind, retaining urine damages the bladder. This statement probably has not much to do with what you said.

Kalecrew profile image
Kalecrew

SteveTheJ thanks for your observation and comment

yes, the bladder was found to be damaged - this may have been due to the long wait for the laser surgery as well as the acute urine retention - there are now "multiple early trabuculations" in his notes ( i think they mean trabeculations)

however thankfully the urine retention is now within normal limits and at the moment frequency is fairly normal, maybe a bit more urgency than before all this started.

thanks for bringing this up and we'll ask the urologist about this and if it will recover when we see him again. I see it can lead to problems as I have just found outlined here

healthline.com/health/trabe...

all best

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