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Another one of many
PSA tested in June 2023 due to a friend who had an issue and encouraged testing. PSA at 43, second test at 40. Biopsy ordered which came in at 4 +5. Moved treatment to UCLA where a PET scan was ordered. Metastatic cancer in 8 locations with 1 lymph node effected, remaining locations spread through different
PSA tested in June 2023 due to a friend who had an issue and encouraged testing. PSA at 43, second test at 40. Biopsy ordered which came in at 4 +5. Moved treatment to UCLA where a PET scan was ordered. Metastatic cancer in 8 locations with 1 lymph node effected, remaining locations spread through different
Wave-Runner
in
Advanced Prostate Cancer
4 days ago
Switched from Lupron to Orgovyx, back to Lupron
I was on Lupron for approximately 7 years. I decided to switch to Orgovyx 6 months ago. I seem to have difficulty with the discipline to take pills at the same time every day. I am switching back to Lupron, but my Urologist wants me to stop Orgovyx and take Bicalutamide for 14 days before getting the
I was on Lupron for approximately 7 years. I decided to switch to Orgovyx 6 months ago. I seem to have difficulty with the discipline to take pills at the same time every day. I am switching back to Lupron, but my Urologist wants me to stop Orgovyx and take Bicalutamide for 14 days before getting the
SF22
in
Advanced Prostate Cancer
5 days ago
WTF!! Something escaped my lens: phase 1 trial for solid tumors
From 2011...I must investigate where they are now, I thought HP90 inhibition through alvespimycin was something new (from one of the articles I have posted today), but it has been around at least since 2011...and look at the results (ok, single patient) on prostate cancer. https://aacrjournals.org/clincancerres
From 2011...I must investigate where they are now, I thought HP90 inhibition through alvespimycin was something new (from one of the articles I have posted today), but it has been around at least since 2011...and look at the results (ok, single patient) on prostate cancer. https://aacrjournals.org/clincancerres
Maxone73
in
Fight Prostate Cancer
5 days ago
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kieran2018
hi everyone, I was diagnosed with stage 4b ovarian cancer in 2020. I underwent surgery had chemo paclitaxel and carboplatin. I commenced on olaparib for two years and my cancer had spread . I then underwent another six cycles of chemo carboplatin and calyx with a partial response. I haven’t been on
hi everyone, I was diagnosed with stage 4b ovarian cancer in 2020. I underwent surgery had chemo paclitaxel and carboplatin. I commenced on olaparib for two years and my cancer had spread . I then underwent another six cycles of chemo carboplatin and calyx with a partial response. I haven’t been on
Kieran2018
in
My Ovacome
5 days ago
TV show: This Morning
Hi there. At my Pilates class this morning, a lady told me that This Morning had done a piece on abdominal surgery and how this can have a longterm effect on your shoulders. I don't know whether this was part of Gynae Cancer Awareness Month. Tried to find it online with no success. Did anyone see it
Hi there. At my Pilates class this morning, a lady told me that This Morning had done a piece on abdominal surgery and how this can have a longterm effect on your shoulders. I don't know whether this was part of Gynae Cancer Awareness Month. Tried to find it online with no success. Did anyone see it
candyapplegrey
in
My Ovacome
6 days ago
Time for Pluvicto?
I had an appointment with the NP at my oncologist's office a couple weeks ago. We discussed the fact that my PSA has been creeping upwards this year and I wondered whether it's just the inevitable failure of Nubeqa, or if my switch from Lupron to Orgovyx last November might be a factor. I started Nubeqa
I had an appointment with the NP at my oncologist's office a couple weeks ago. We discussed the fact that my PSA has been creeping upwards this year and I wondered whether it's just the inevitable failure of Nubeqa, or if my switch from Lupron to Orgovyx last November might be a factor. I started Nubeqa
velobard
in
Advanced Prostate Cancer
7 days ago
PSA rise, when would one be concerned???
Stage 4 at diagnosis 2y ago with Gleason 9spread in bone in pelvice and possibly elsewhere. Had chemo and radiotherapy (to prostate) Lupron injections 3 monthly PSA results May23 0.08 Dec23 0.25 Feb24 0.44 June24 0.58 Sep24 1.1 I know they are not massive PSA values, but it's an upward trajectory. What
Stage 4 at diagnosis 2y ago with Gleason 9spread in bone in pelvice and possibly elsewhere. Had chemo and radiotherapy (to prostate) Lupron injections 3 monthly PSA results May23 0.08 Dec23 0.25 Feb24 0.44 June24 0.58 Sep24 1.1 I know they are not massive PSA values, but it's an upward trajectory. What
Mrtroxely
in
Advanced Prostate Cancer
7 days ago
Kindly suggest the most appropriate next steps and questions for MO!
hi all! My dad was diagnosed in Feb2024 with metastatic prostate cancer, Gleason 8 and PSA 24. He is majorly asymptomatic. His PSA dropped to 0.16 and now has risen to 1.6 over a period of 2.5 months. He has been on hormone therapy and taking abireterone and prednisone daily. He got orchidectomy done
hi all! My dad was diagnosed in Feb2024 with metastatic prostate cancer, Gleason 8 and PSA 24. He is majorly asymptomatic. His PSA dropped to 0.16 and now has risen to 1.6 over a period of 2.5 months. He has been on hormone therapy and taking abireterone and prednisone daily. He got orchidectomy done
Justgettingitright
in
Advanced Prostate Cancer
7 days ago
Screening for Colorectal Cancer
There are several tests, some of which can be done at home.👏😃 Most people should begin screening for colorectal cancer soon after turning 45.🤔👍 You may need to be tested [u]
earlier than 45, or more often than other people
[/u], if you have: * Inflammatory bowel disease such as Crohn's disease
There are several tests, some of which can be done at home.👏😃 Most people should begin screening for colorectal cancer soon after turning 45.🤔👍 You may need to be tested [u]
earlier than 45, or more often than other people
[/u], if you have: * Inflammatory bowel disease such as Crohn's disease
GCCA-Survivor
Administrator
in
Colon Cancer Connected
8 days ago
Prostate Cancer Buddy Experience
Hi - i volunteer as a prostate cancer buddy (working for MacMillan a charity very much embedded in the UK National Health Service). The idea is that I provide non medical peer to peer support to a fellow PCa patient as part of their support network. The objective is to provide support, share experiences
Hi - i volunteer as a prostate cancer buddy (working for MacMillan a charity very much embedded in the UK National Health Service). The idea is that I provide non medical peer to peer support to a fellow PCa patient as part of their support network. The objective is to provide support, share experiences
PSA680
in
Advanced Prostate Cancer
9 days ago
When others talk about you, what do you want them to say?
How do you want your friends, family, and others to talk about you, vis a vie prostate cancer? When others talk about you, what do you want them to say?
How do you want your friends, family, and others to talk about you, vis a vie prostate cancer? When others talk about you, what do you want them to say?
Darryl
Partner
in
Advanced Prostate Cancer
9 days ago
SCT journey update No.4
Hi all, just to give you an update on my journey towards my *Allogenic Stem cell Transplant. Last tests @ Addenbrookes yesterday, was a very early start as Lung function testing was @ 8.30am and it’s about 2 hour journey. Wife and I were up about 3-4am ( to be fair, couldn’t sleep anyway ) The drive
Hi all, just to give you an update on my journey towards my *Allogenic Stem cell Transplant. Last tests @ Addenbrookes yesterday, was a very early start as Lung function testing was @ 8.30am and it’s about 2 hour journey. Wife and I were up about 3-4am ( to be fair, couldn’t sleep anyway ) The drive
LFCLove
in
MPN Voice
2 months ago
Phase 1 trial: Oncolytic Adenovirus TILT-123 in Advanced Solid Cancers, no prostate cancer but very interesting
Oncolytic viruses are promising! Prostate cancer is a solid tumor with an immune suppressing micro environment but still, also some of the tumores in this phase 1 study are hostile to the immune system https://aacrjournals.org/clincancerres/article/30/17/3715/747277/Safety-Efficacy-and-Biological-Data-of-T-Cell
Oncolytic viruses are promising! Prostate cancer is a solid tumor with an immune suppressing micro environment but still, also some of the tumores in this phase 1 study are hostile to the immune system https://aacrjournals.org/clincancerres/article/30/17/3715/747277/Safety-Efficacy-and-Biological-Data-of-T-Cell
Maxone73
in
Advanced Prostate Cancer
9 days ago
Consider that it is observational and sponsored by Bayer but...Darolutamide Bests Other Androgen Receptor Inhibitors in nmCRPC
Worth knowing, even if we suppose that the key to beat prostate cancer is a combo therapy... "Patients with nonmetastatic castration-resistant prostate cancer (nmCRPC) have a lower risk of treatment discontinuation and disease progression if they receive darolutamide rather than other androgen receptor
Worth knowing, even if we suppose that the key to beat prostate cancer is a combo therapy... "Patients with nonmetastatic castration-resistant prostate cancer (nmCRPC) have a lower risk of treatment discontinuation and disease progression if they receive darolutamide rather than other androgen receptor
Maxone73
in
Advanced Prostate Cancer
9 days ago
Abiraterone/prednisone plus olaparib extends time to progression in BRCA/ATM mutated prostate cancer.
I have already talked about this data, but it's worth repeating...plus when I see dr Hussain I always smile! “Our data showed that the combination therapy resulted in more than two-fold increase in the median time to disease progression compared to single-agents or sequentially following progression
I have already talked about this data, but it's worth repeating...plus when I see dr Hussain I always smile! “Our data showed that the combination therapy resulted in more than two-fold increase in the median time to disease progression compared to single-agents or sequentially following progression
Maxone73
in
Advanced Prostate Cancer
9 days ago
Was hoping not to post again, but...
Hello everyone! I posted this over three years ago: I am 53. Had RP in October (2020). Pathology was G9 pT3bN1M0 with ECE, SVI and positive margin. Had 39 IMRT salvage radiation sessions. Just had my 3rd three month Lupron injection and take the 4 horse pills daily. Right now my PSA and testosterone
Hello everyone! I posted this over three years ago: I am 53. Had RP in October (2020). Pathology was G9 pT3bN1M0 with ECE, SVI and positive margin. Had 39 IMRT salvage radiation sessions. Just had my 3rd three month Lupron injection and take the 4 horse pills daily. Right now my PSA and testosterone
Harrisonhoyle
in
Advanced Prostate Cancer
10 days ago
Duke study about testosterone's dual PCa effectiveness
https://corporate.dukehealth.org/news/study-solves-testosterones-paradoxical-effects-prostate-cancer Its good to suppress it until its bad to not supplement it... AKA BAT but perhaps applicable someday to advanced PCa patients.
https://corporate.dukehealth.org/news/study-solves-testosterones-paradoxical-effects-prostate-cancer Its good to suppress it until its bad to not supplement it... AKA BAT but perhaps applicable someday to advanced PCa patients.
Derf4223
in
Advanced Prostate Cancer
10 days ago
Study Solves Testosterone’s Paradoxical Effects in Prostate Cancer, Duke Health, Published September 04, 2024
This research appears to be a major breakthrough in our understanding of PCa's development and progression. It is also new evidence that further validates Dr. Abraham Morgantaler's testosterone "Saturation Model" and the underlying principles that make BAT effective. There is much in the Nature Communications
This research appears to be a major breakthrough in our understanding of PCa's development and progression. It is also new evidence that further validates Dr. Abraham Morgantaler's testosterone "Saturation Model" and the underlying principles that make BAT effective. There is much in the Nature Communications
cujoe
in
Fight Prostate Cancer
10 days ago
we will soon know more about Nubeqa
"Bayer will present new oncology data, including a late-breaking, comprehensive analysis from the Phase III ARANOTE trial investigating NUBEQA® (darolutamide) plus androgen deprivation therapy (ADT) in patients with metastatic hormone-sensitive prostate cancer (mHSPC), at the European Society for Medical
"Bayer will present new oncology data, including a late-breaking, comprehensive analysis from the Phase III ARANOTE trial investigating NUBEQA® (darolutamide) plus androgen deprivation therapy (ADT) in patients with metastatic hormone-sensitive prostate cancer (mHSPC), at the European Society for Medical
Maxone73
in
Advanced Prostate Cancer
11 days ago
BAT - Testosterone Solved?
https://corporate.dukehealth.org/news/study-solves-testosterones-paradoxical-effects-prostate-cancer Looks like a really interesting study, and implies that reducing T during early cancer stages is a good thing, but it may not be a good thing in advanced PCa later - and actually, increasing T (high
https://corporate.dukehealth.org/news/study-solves-testosterones-paradoxical-effects-prostate-cancer Looks like a really interesting study, and implies that reducing T during early cancer stages is a good thing, but it may not be a good thing in advanced PCa later - and actually, increasing T (high
Don_1213
in
Advanced Prostate Cancer
11 days ago
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