Duke study about testosterone's dual PCa effectiveness

[Derf4223]

corporate.dukehealth.org/ne...

Its good to suppress it until its bad to not supplement it... AKA BAT but perhaps applicable someday to advanced PCa patients.

[HikerWife]

Really interesting, saved to The Big Ugly files!! Thanks for posting.

[Yzinger]

This is a confusing read....the paragraph below for instance seems to state that if T is low cancer cells PROLIFERATE. Isn't that the opposite of what we know?

******************The researchers found that prostate cancer cells are hardwired with a system that allows them to proliferate when the levels of testosterone are very low. But when hormone levels are elevated to resemble those present in the normal prostate, the cancer cells differentiate.

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..yes there is more to the article but I find this to be confusing.

[Justfor_ in reply to Yzinger]

Low or very low levels don't align with castrate ones. Quantitavely: Low <250 vs castrate <50. Very low somewhere in between.

[Derf4223 in reply to Yzinger]

From Dr. G00gle, about cancer cell differentiation.

"In cancer, this describes how much or how little tumor tissue looks like the normal tissue it came from. Well-differentiated cancer cells look more like normal cells and tend to grow and spread more slowly than poorly differentiated or undifferentiated cancer cells."