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Ibrance and TMarkers
Anyone out there with 4+ years of Ibrance and with tumour markers over the normal range? I have a single mets to bone (T9) and I have been taking Ibrance and Letrozole now for 3 years and 9 months. Last month my CA 15-3 went over the normal range to 34.8, my CEA was normal. I had a very bad cold
Anyone out there with 4+ years of Ibrance and with tumour markers over the normal range? I have a single mets to bone (T9) and I have been taking Ibrance and Letrozole now for 3 years and 9 months. Last month my CA 15-3 went over the normal range to 34.8, my CEA was normal. I had a very bad cold
Gramat
in
SHARE Metastatic Breast Cancer
5 months ago
PSA of <0.1 undetectable?
I am on ADT, lupron and Zytiga, at Kaiser Oakland. My latest PSA came back as <0.1. My MO sent me a message with the results: "congratulations, great news, your PSA is undetectable!" I thought undetectable was 0.01, is it more likely she misread the number or that the lab used by Kaiser only reports
I am on ADT, lupron and Zytiga, at Kaiser Oakland. My latest PSA came back as <0.1. My MO sent me a message with the results: "congratulations, great news, your PSA is undetectable!" I thought undetectable was 0.01, is it more likely she misread the number or that the lab used by Kaiser only reports
pj1121
in
Advanced Prostate Cancer
5 months ago
Can i take vacation when already 5 years PSA < 0.01
Cancer of the prostate and pelvic lymph nodes found with PET 1, MRI, biopsy, PSA=100. - After 6 cycles of chemotherapy with docetaxel and ADT-ELIGARD with PET 2 and PET 3 show a rapid decrease in the size of the lymph nodes and their emission of SUV, as well as the disappearance of several of them
Cancer of the prostate and pelvic lymph nodes found with PET 1, MRI, biopsy, PSA=100. - After 6 cycles of chemotherapy with docetaxel and ADT-ELIGARD with PET 2 and PET 3 show a rapid decrease in the size of the lymph nodes and their emission of SUV, as well as the disappearance of several of them
Vasili
in
Advanced Prostate Cancer
5 months ago
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Moved from Abi to Nubeqa and saw a PSA increase
I recently switched from Abiraterone/Prednisone to Nubeqa because of the high blood pressure that I had with Abi requiring additional BP meds. I was previously .058 a month ago when I switched and .109 today, almost double in a month. Any one with experience with this switch?
I recently switched from Abiraterone/Prednisone to Nubeqa because of the high blood pressure that I had with Abi requiring additional BP meds. I was previously .058 a month ago when I switched and .109 today, almost double in a month. Any one with experience with this switch?
Steel67
in
Advanced Prostate Cancer
5 months ago
Slowly Rising PSA - Getting Nervous
It seems in the last 4 months it has been rising more. Doctors are waiting until in gets to the standard 0.2 before starting radiation. I do understand why they need to wait as the PSA isn't high enough yet for the risk/reward of treatment. 03/17/2023 0.029 04/22/2023 0.032 08/23/2023 0.046 12/07/2023
It seems in the last 4 months it has been rising more. Doctors are waiting until in gets to the standard 0.2 before starting radiation. I do understand why they need to wait as the PSA isn't high enough yet for the risk/reward of treatment. 03/17/2023 0.029 04/22/2023 0.032 08/23/2023 0.046 12/07/2023
raisin123
in
Advanced Prostate Cancer
5 months ago
Colon cancer after CLL diagnosis
Things were going so well. At 63 and while living in France for a work contract, my husband, who already has HF low EF (which I managed to improve recently to an EF of 43%) and who has always been in excellent shape with diet and physical exercise, was diagnosed with CLL in the spring of 2023 . We
Things were going so well. At 63 and while living in France for a work contract, my husband, who already has HF low EF (which I managed to improve recently to an EF of 43%) and who has always been in excellent shape with diet and physical exercise, was diagnosed with CLL in the spring of 2023 . We
Minou1
in
CLL Support
3 months ago
? Cover required for endometrial biopsy
I have been on prednisolone for over 2 years now and still on 10mg. I have a hysteroscopy and endometrial biopsy planned tomorrow and although this is only a minor procedure with no general anaesthetic or sedation, I’m just wondering whether I will need any extra steroid cover? Does anyone have any knowledge
I have been on prednisolone for over 2 years now and still on 10mg. I have a hysteroscopy and endometrial biopsy planned tomorrow and although this is only a minor procedure with no general anaesthetic or sedation, I’m just wondering whether I will need any extra steroid cover? Does anyone have any knowledge
PPop
in
PMRGCAuk
5 months ago
6 years now and PSA <0.01 is it time for a vacation?
Hello, after chemotherapy, STRT of the prostate, I have been taking Eligard hormone therapy for 6 years now and PSA <0.01 is it time for a vacation?
Hello, after chemotherapy, STRT of the prostate, I have been taking Eligard hormone therapy for 6 years now and PSA <0.01 is it time for a vacation?
Vasili
in
Advanced Prostate Cancer
5 months ago
Enhancing my urinating experience?
Guys, Several weeks ago I started experiencing slow and weak urine stream for first time since diagnosis almost 6 years ago. This, coupled with rise in PSA, triggered my oncologist to order both MRI and PSMA scan. Would appear things are progressing and got referrals to radiation oncologist and urologist
Guys, Several weeks ago I started experiencing slow and weak urine stream for first time since diagnosis almost 6 years ago. This, coupled with rise in PSA, triggered my oncologist to order both MRI and PSMA scan. Would appear things are progressing and got referrals to radiation oncologist and urologist
3putt
in
Advanced Prostate Cancer
5 months ago
When to do certain blood tests and why.
Just coming up on my 6 month anniversary of radiation and my 2 months prior to radiation and 4 months post Lupron while on radiation. So I have been off Lupron for 2 months. I had my annual physical yesterday and my GP had ordered complete blood panel with thyroid and PSA. There were no issues with blood
Just coming up on my 6 month anniversary of radiation and my 2 months prior to radiation and 4 months post Lupron while on radiation. So I have been off Lupron for 2 months. I had my annual physical yesterday and my GP had ordered complete blood panel with thyroid and PSA. There were no issues with blood
Mgtd
in
Advanced Prostate Cancer
5 months ago
64Cu-SAR-bisPSMA Is Safe and Highly Effective in Detecting Tumours in Prostate Cancer Patients: results from COBRA trial
This could mean being way more precise in finding micro metastasis and in guided surgery! https://www.urotoday.com/recent-abstracts/urologic-oncology/prostate-cancer/149903-initial-cobra-results-clarity-s-sar-bispsma-is-safe-and-highly-effective-in-detecting-tumours-in-prostate-cancer-patients-phase
This could mean being way more precise in finding micro metastasis and in guided surgery! https://www.urotoday.com/recent-abstracts/urologic-oncology/prostate-cancer/149903-initial-cobra-results-clarity-s-sar-bispsma-is-safe-and-highly-effective-in-detecting-tumours-in-prostate-cancer-patients-phase
Maxone73
in
Advanced Prostate Cancer
3 months ago
High volume, advanced metastatic prostate cancer
Hello. I am looking for guidance. My dad (now 81) was diagnosed with metastatic prostate cancer at the initial point of diagnosis in the ER on 10/25/2022. It had spread to 8 bones and was all over his spine, hip, base of skull, etc, but also as far as the base of the skull, and shoulder. His PSA was
Hello. I am looking for guidance. My dad (now 81) was diagnosed with metastatic prostate cancer at the initial point of diagnosis in the ER on 10/25/2022. It had spread to 8 bones and was all over his spine, hip, base of skull, etc, but also as far as the base of the skull, and shoulder. His PSA was
lgutman
in
Advanced Prostate Cancer
3 months ago
Stopping Abi?
I meet with my MO Thursday. We will likely discuss coming off Abiraterone, as my 2 year anniversary is upcoming. Probably continue on Eligard for another year, following stampede trial. PSA reached undetectable early in my treatment and remains undetectable. SE. aren’t fun, but manageable. Don’t
I meet with my MO Thursday. We will likely discuss coming off Abiraterone, as my 2 year anniversary is upcoming. Probably continue on Eligard for another year, following stampede trial. PSA reached undetectable early in my treatment and remains undetectable. SE. aren’t fun, but manageable. Don’t
Gatodd
in
Advanced Prostate Cancer
5 months ago
Dizziness from Zytiga/prednisone?
my MO tried something out of the ordinary - let me have a 'vacation' from ADT for a short while, even though i am Castrate -resistant. he was hoping we coudl keep PSA down while my Testosterone recovered, to see if that woudl make me feel better. to use his words, i have 'complained bitterly of the
my MO tried something out of the ordinary - let me have a 'vacation' from ADT for a short while, even though i am Castrate -resistant. he was hoping we coudl keep PSA down while my Testosterone recovered, to see if that woudl make me feel better. to use his words, i have 'complained bitterly of the
Tonwantonga
in
Advanced Prostate Cancer
5 months ago
How Genomic Biomarkers are Shaping Treatment Decisions
Big Data and AI are powerful... https://www.urotoday.com/video-lectures/prostate-cancer-genomic-classifier/video/mediaitem/3634-deciphering-prostate-cancer-how-genomic-biomarkers-are-shaping-treatment-decisions-paul-nguyen.html
Big Data and AI are powerful... https://www.urotoday.com/video-lectures/prostate-cancer-genomic-classifier/video/mediaitem/3634-deciphering-prostate-cancer-how-genomic-biomarkers-are-shaping-treatment-decisions-paul-nguyen.html
Maxone73
in
Advanced Prostate Cancer
5 months ago
Dual Action Hormone Therapy Targeting Two Parts of Androgen Receptor for mCRPC
Phase I/II trial of masofaniten combined with enzalutamide, a novel hormonal therapy for mCRPC. Masofaniten, a first-in-class N-terminal ligand antagonist for the androgen receptor, shows promise in overcoming resistance to current hormonal therapies. Hopefully a new weapon for us!
Phase I/II trial of masofaniten combined with enzalutamide, a novel hormonal therapy for mCRPC. Masofaniten, a first-in-class N-terminal ligand antagonist for the androgen receptor, shows promise in overcoming resistance to current hormonal therapies. Hopefully a new weapon for us!
Maxone73
in
Advanced Prostate Cancer
5 months ago
Anyone tried cabazitaxel (Jevtana) monotherapy?
If you've tried cabazitaxel [u]
without
[/u] ADT, I would appreciate hearing about your side effects and effectiveness. I'm currently in excellent shape at age 72. Previously I tolerated docetaxel (which along with radiation of abdominal lymph nodes helped me return to undetectable PSA for 4+ years
If you've tried cabazitaxel [u]
without
[/u] ADT, I would appreciate hearing about your side effects and effectiveness. I'm currently in excellent shape at age 72. Previously I tolerated docetaxel (which along with radiation of abdominal lymph nodes helped me return to undetectable PSA for 4+ years
ron_bucher
in
Advanced Prostate Cancer
5 months ago
What category of Intermediate Risk Am I?
I am trying to make a decision regarding HT with RT. I am 78. I have CKD 3b, and a solitary kidney. I am 6.5 years in remission from UTUC kidney cancer. A number of papers indicate that HT could be detrimental to my kidney. Those with FIR PCa could avoid HT with little risk. The following is defined
I am trying to make a decision regarding HT with RT. I am 78. I have CKD 3b, and a solitary kidney. I am 6.5 years in remission from UTUC kidney cancer. A number of papers indicate that HT could be detrimental to my kidney. Those with FIR PCa could avoid HT with little risk. The following is defined
Nordman
in
Advanced Prostate Cancer
3 months ago
Pinostilbene inhibits the Enz-resistant CRPC cell line by inhibiting AR variant 7
i take pterostilbene daily which pinostilbene is a metabolite of pterostilbene. in any event if you are failing on enzalutamide or any PCa warrior you probably should take pterostilbene. Below is a 2023 in-depth article https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10550987/ Pinostilbene inhibits
i take pterostilbene daily which pinostilbene is a metabolite of pterostilbene. in any event if you are failing on enzalutamide or any PCa warrior you probably should take pterostilbene. Below is a 2023 in-depth article https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10550987/ Pinostilbene inhibits
KocoPr
in
Fight Prostate Cancer
5 months ago
PSA +
Is a PSA increase from .13 to .20 a concern? I'm on Eligard and Zytiga & Prednisone + Xgeva.
Is a PSA increase from .13 to .20 a concern? I'm on Eligard and Zytiga & Prednisone + Xgeva.
TommyCarz2
in
Advanced Prostate Cancer
5 months ago
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