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Feeling let down
Just a bit of a rant really as feeling let down by the system. I’ve been back and forth to the GP’s over the years with Raynuards, rosacea, recently a sun spot that turned cancerous, depression, fainting etc and no one up until me doing my research has ever joined the all the constellation of symptoms
Just a bit of a rant really as feeling let down by the system. I’ve been back and forth to the GP’s over the years with Raynuards, rosacea, recently a sun spot that turned cancerous, depression, fainting etc and no one up until me doing my research has ever joined the all the constellation of symptoms
Fizzwhizz
in
Thyroid UK
5 months ago
Magnesium, zinc and calcium
Nearly a year after ADT and all clear with testosterone recovering well. Been advised by a fellow runner to try a supplement of magnesium, zinc and calcium. The Onco has no objections. Are there reasons no too? Thank you.
Nearly a year after ADT and all clear with testosterone recovering well. Been advised by a fellow runner to try a supplement of magnesium, zinc and calcium. The Onco has no objections. Are there reasons no too? Thank you.
Runner1957
in
Prostate Cancer Network
5 months ago
good evening....
I'm trying to stay positive and help everyone come up with ideas for journaling, artwork, ect....I try not to get carried away with my posts.....trying not to be too pushy....will you please let me know if i get too carried away
I'm trying to stay positive and help everyone come up with ideas for journaling, artwork, ect....I try not to get carried away with my posts.....trying not to be too pushy....will you please let me know if i get too carried away
mizzou7016
in
Anxiety and Depression Support
7 months ago
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Testosterone volatility
My testosterone was measured @ 490 in 2014 when I was DX with PCa Gleason 6, it was measured again in 2016 at 463. It was not measured again until after I started on ADT and it has been >7 ever since. Is there a way for me to extrapolate what it would have been in 2021 when I was DX with Gleason
My testosterone was measured @ 490 in 2014 when I was DX with PCa Gleason 6, it was measured again in 2016 at 463. It was not measured again until after I started on ADT and it has been >7 ever since. Is there a way for me to extrapolate what it would have been in 2021 when I was DX with Gleason
Scout4answers
in
Prostate Cancer Network
5 months ago
Unsure about increasing T3
Hi Everyone, I’ve had my appointment with my thyroid specialist today and she wants me to increase my T3 from 15mcg a day to 25mcg a day and keep levo at 100mcg. However I’m really hesitant to do this as last time I increased my T3 (see my original post below) I got my T4 to 6 and felt awful. Plus I
Hi Everyone, I’ve had my appointment with my thyroid specialist today and she wants me to increase my T3 from 15mcg a day to 25mcg a day and keep levo at 100mcg. However I’m really hesitant to do this as last time I increased my T3 (see my original post below) I got my T4 to 6 and felt awful. Plus I
Fallleaves
in
Thyroid UK
5 months ago
Hypo, Hashi's, Menopause & Testosterone
My last sex hormone blood test showed my testosterone at [u]
1.91!
[/u]
(range of 0.10-1.42) This concerns my Endo doc who has been amazing treating my thyroid issues, but has now informed me that AFTER
age 60
you shouldn't BEGIN hrt. 😪 So, that's out of the question for me since
My last sex hormone blood test showed my testosterone at [u]
1.91!
[/u]
(range of 0.10-1.42) This concerns my Endo doc who has been amazing treating my thyroid issues, but has now informed me that AFTER
age 60
you shouldn't BEGIN hrt. 😪 So, that's out of the question for me since
wavedancers
in
Thyroid UK
5 months ago
Treatment Resistant Depression
I have had depression since my 20’s and likely in teens. I’m now 56 and my meds are no longer working like they once did. I’m going to be meeting with a clinic about other options ie: ECT etc. I’m very scared and anxious as this feels next level to me in my illness. Have you tried ECT and/or Esketamine
I have had depression since my 20’s and likely in teens. I’m now 56 and my meds are no longer working like they once did. I’m going to be meeting with a clinic about other options ie: ECT etc. I’m very scared and anxious as this feels next level to me in my illness. Have you tried ECT and/or Esketamine
Doubledog
in
Major Depressive Disorder (MDD) Support
7 months ago
Low testosterone is associated with extremely poor survival metrics, post-ADT.
These companion plots compare: (A) median survival times, (B) PSA doubling times, and (C) Time to PSA Failure for two different levels of testosterone: Low and Normal. The low testosterone has a median value of 162 ng/dL [120-236] and the average normal T = 680 ng/dL. The cohort is 58 men with unfavorable
These companion plots compare: (A) median survival times, (B) PSA doubling times, and (C) Time to PSA Failure for two different levels of testosterone: Low and Normal. The low testosterone has a median value of 162 ng/dL [120-236] and the average normal T = 680 ng/dL. The cohort is 58 men with unfavorable
janebob99
in
Prostate Cancer Network
5 months ago
Low Testosterone reduces Survival by a huge amount.
This plot compares prostate cancer specific mortality probability versus time for two different levels of testosterone: Low and Normal. The low testosterone has a median value of 162 ng/dL [120-236] and the average normal T = 680 ng/dL. The cohort is 58 men with unfavorable intermediate risk who underwent
This plot compares prostate cancer specific mortality probability versus time for two different levels of testosterone: Low and Normal. The low testosterone has a median value of 162 ng/dL [120-236] and the average normal T = 680 ng/dL. The cohort is 58 men with unfavorable intermediate risk who underwent
janebob99
in
Prostate Cancer Network
5 months ago
My own PSA values over time: 70% drop in just 3 months on Dutasteride and no ADT
Here are my own PSA values versus time plot. You can see there is an exponential rise in PSA starting at around 6/1/23, and doubling from PSA = 5 to 10 in about 8 months. My MRI at PSA = 10 showed a T3a tumor about 1.3 cm long (PIRADS 5). A subsequent targeted biopsy showed Gleason 3+4 in 4 cores,
Here are my own PSA values versus time plot. You can see there is an exponential rise in PSA starting at around 6/1/23, and doubling from PSA = 5 to 10 in about 8 months. My MRI at PSA = 10 showed a T3a tumor about 1.3 cm long (PIRADS 5). A subsequent targeted biopsy showed Gleason 3+4 in 4 cores,
janebob99
in
Prostate Cancer Network
5 months ago
Doubling Times and PSA acceleration - Part II
This is a more realistic schematic plot of PSA levels increasing over time at an ever faster rate (acceleration). What could cause this? My theory is that as the tumor grows, the number of androgen receptors (ARs) increases proportionally. That makes sense...more PCa cells inside a tumor...more ARs
This is a more realistic schematic plot of PSA levels increasing over time at an ever faster rate (acceleration). What could cause this? My theory is that as the tumor grows, the number of androgen receptors (ARs) increases proportionally. That makes sense...more PCa cells inside a tumor...more ARs
janebob99
in
Prostate Cancer Network
5 months ago
Vitamin and mineral deficiencies/Thyroid dysfunction.. Chicken or Egg?
Before I spend my hard earned money on going to a private ENDO because the NHS is failing me I wanted to ask what you all thought about the problem of iron deficiency and vitamin D deficiency and how this relates to underactive thyroid . I read a lot here about how these vitamins should be optimal for
Before I spend my hard earned money on going to a private ENDO because the NHS is failing me I wanted to ask what you all thought about the problem of iron deficiency and vitamin D deficiency and how this relates to underactive thyroid . I read a lot here about how these vitamins should be optimal for
doingitfordad
in
Thyroid UK
10 months ago
Non metastasis castrate resistant
When you are on ADT and become Non metastatic Castrate resistant and your testosterone levels are below zero, what is the cancer feeding off to cause the PSA to still rise? Hoping for your replies so as to give me some understanding. Thank you.
When you are on ADT and become Non metastatic Castrate resistant and your testosterone levels are below zero, what is the cancer feeding off to cause the PSA to still rise? Hoping for your replies so as to give me some understanding. Thank you.
Sailameme
in
Advanced Prostate Cancer
5 months ago
help with bloods.
I have been on HRT for 5 years. I'm currently on 300mg Utrogestan (100mg to 200mg 17/10 then 200mg 25 on 3 days off then up to 300mg on 11/2/24 25 days on 3 days off) and 100 evorel patch plus 1 pump of tostran gel twice a week. I have been having bleeds since June 23 (had an internal scan and biopsy
I have been on HRT for 5 years. I'm currently on 300mg Utrogestan (100mg to 200mg 17/10 then 200mg 25 on 3 days off then up to 300mg on 11/2/24 25 days on 3 days off) and 100 evorel patch plus 1 pump of tostran gel twice a week. I have been having bleeds since June 23 (had an internal scan and biopsy
WendyW1964
in
Menopause and Perimenopause Support
5 months ago
post menopause bleeding
Hi all, I’m a 64 year old woman whose periods stopped when I was 50, I chose HRT after a few years of non stop daytime sweats, zero concentration and bursting into tears at the drop of a hat 🙈 I stopped the HRT back in 2020 but had to start it again last year as the sweats returned with a vengeance
Hi all, I’m a 64 year old woman whose periods stopped when I was 50, I chose HRT after a few years of non stop daytime sweats, zero concentration and bursting into tears at the drop of a hat 🙈 I stopped the HRT back in 2020 but had to start it again last year as the sweats returned with a vengeance
NanaFifi
in
Women's Health
5 months ago
women of a certain age
ok so it may be time to accept the fact that it may not be just my thyroid causing my issues.?so I’ve read quite a lot about her and think as I didn’t have a good run with levothyroxine I don’t think combining hrt tables as well is the way to go so after reading lots I’m thinking get with a progesterone
ok so it may be time to accept the fact that it may not be just my thyroid causing my issues.?so I’ve read quite a lot about her and think as I didn’t have a good run with levothyroxine I don’t think combining hrt tables as well is the way to go so after reading lots I’m thinking get with a progesterone
Bobby25
in
Thyroid UK
5 months ago
Just some new Information about AI
Came across this article a couple days ago. https://www.news-medical.net/news/20210924/Researchers-identify-two-subtypes-of-metastatic-prostate-cancer.aspx#:~:text=Building%20off%20of%20earlier%20studies%20that%20discovered%20clinically,into%20two%20types%20known%20as%20luminal%20and%20basal AI has
Came across this article a couple days ago. https://www.news-medical.net/news/20210924/Researchers-identify-two-subtypes-of-metastatic-prostate-cancer.aspx#:~:text=Building%20off%20of%20earlier%20studies%20that%20discovered%20clinically,into%20two%20types%20known%20as%20luminal%20and%20basal AI has
chefjlu
in
Advanced Prostate Cancer
5 months ago
Revised Plot of PSA vs Testosterone: Estrogen vs Lupron ADT
Ugh...I made a BIG mistake on the previous posting! I just realized that Dr. Morgentaler had listed the Testosterone level in unusual units (
ng/mL
), not the usual units of (
ng/dL)
. So, my X-axis was off by a factor of 10. Here is the revised plot. The exciting discovery is that the
Ugh...I made a BIG mistake on the previous posting! I just realized that Dr. Morgentaler had listed the Testosterone level in unusual units (
ng/mL
), not the usual units of (
ng/dL)
. So, my X-axis was off by a factor of 10. Here is the revised plot. The exciting discovery is that the
janebob99
in
Advanced Prostate Cancer
5 months ago
Morgentaler Saturation Model: PSA vs Testosterone - Estrogen Patch vs Lupron ADT
This is a plot of % reduction in PSA from a Maximum Value versus Testosterone, for two different datasets: Estrogen Patch and Lupron ADT. Both curves (red and green lines) show a linear response starting from (0,0), up to about 200-250 ng/dL. Then, the lines curve over to a lower slope (especially
This is a plot of % reduction in PSA from a Maximum Value versus Testosterone, for two different datasets: Estrogen Patch and Lupron ADT. Both curves (red and green lines) show a linear response starting from (0,0), up to about 200-250 ng/dL. Then, the lines curve over to a lower slope (especially
janebob99
in
Advanced Prostate Cancer
5 months ago
Another brother passes
My friend, George, passed this morning after a two year battle. He was DX'd at 85 with prostate cancer (PSA of 1200) behind his eye which spread to his brain. Failed ADT, chemo and Pluvicto. He was not on this forum. He was very active, skied 120 days a year, biked the rest. He and his wife went to
My friend, George, passed this morning after a two year battle. He was DX'd at 85 with prostate cancer (PSA of 1200) behind his eye which spread to his brain. Failed ADT, chemo and Pluvicto. He was not on this forum. He was very active, skied 120 days a year, biked the rest. He and his wife went to
gsun
in
Advanced Prostate Cancer
5 months ago
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