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Experiences with
Prostate-specific antigen (PSA)
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CTC circulating tumor cell count
I haven’t seen too much mention of CTC tests when
PSA
rises. Some rises at very low levels are not clearly correlated or confirmed by PET scans. So why isn’t CTC used, too expensive, inaccurate, most men lack a baseline test?
I haven’t seen too much mention of CTC tests when
PSA
rises. Some rises at very low levels are not clearly correlated or confirmed by PET scans. So why isn’t CTC used, too expensive, inaccurate, most men lack a baseline test?
Steel67
in
Advanced Prostate Cancer
2 months ago
ALP AND RADIUM 223
We thought the
PSA
count wasn’t of much relevance when someone is on radium 223 as the Pca on the bones releases
PSA
when it’s being attacked by the radium - is this incorrect and should we be worried? Thanks All
We thought the
PSA
count wasn’t of much relevance when someone is on radium 223 as the Pca on the bones releases
PSA
when it’s being attacked by the radium - is this incorrect and should we be worried? Thanks All
NLondon43
in
Advanced Prostate Cancer
6 months ago
Proton Beam radiation
Proton beam radiation: 30 sessions = 72 Gy, result
PSA
0,014 (undetectable), minor inkontinence (pads). I am very happy about the outcome. Living in Germany: insurances cover the cost( approx 50k)
Proton beam radiation: 30 sessions = 72 Gy, result
PSA
0,014 (undetectable), minor inkontinence (pads). I am very happy about the outcome. Living in Germany: insurances cover the cost( approx 50k)
EBBEFLUT
in
Advanced Prostate Cancer
3 months ago
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Expanded label sought for 177Lu-PSMA-617 in prostate cancer: about time
Specifically, a
PSA
decline greater than 50% was observed in 57.6% of patients who received 177Lu-PSMA-617, vs 20.4% of patients who received a change in ARPI." https://www.urologytimes.com/view/expanded-label-sought-for-177lu-psma-617-in-prostate-cancer
Specifically, a
PSA
decline greater than 50% was observed in 57.6% of patients who received 177Lu-PSMA-617, vs 20.4% of patients who received a change in ARPI." https://www.urologytimes.com/view/expanded-label-sought-for-177lu-psma-617-in-prostate-cancer
Maxone73
in
Advanced Prostate Cancer
4 months ago
PSA showing .014 - concerned?
I had RP 3/22,
PSA
went up to .095 3 months after. I started Orgovyx on 8/15/22 had radiation Jan & Feb 23 and started Abi 4/23. All my psa's have been 0 since 10/22. Now it is at .014. I see my oncologist next Tuesday but I don't want to wait for his answer. How bad of a sign is this?
I had RP 3/22,
PSA
went up to .095 3 months after. I started Orgovyx on 8/15/22 had radiation Jan & Feb 23 and started Abi 4/23. All my psa's have been 0 since 10/22. Now it is at .014. I see my oncologist next Tuesday but I don't want to wait for his answer. How bad of a sign is this?
VanHalen84
in
Advanced Prostate Cancer
5 months ago
Dad's PSA risen from 0.01 to 0.05 in 2 months, 2 years post SRT. Any chance that there is no further progression?
PSA
has risen 3 times in a row. I understand the figure is still low, but is this a definite indication that it will progress, or is there a chance that
PSA
can stabilize or fluctuate and not progress further?
PSA
has risen 3 times in a row. I understand the figure is still low, but is this a definite indication that it will progress, or is there a chance that
PSA
can stabilize or fluctuate and not progress further?
MsBoBo
in
Advanced Prostate Cancer
6 months ago
Doublet Therapy for Metastatic Prostate Cancer
My dad, 73 (Initial
PSA
151, Gleason 9, 4 small mets to pelvis, spine, tailbone) had an appointment today, and his MO indicated that he would like to proceed with doublet therapy. I wasn't aware he would be a candidate for this treatment given his mets. Curious to hear others input on this.
My dad, 73 (Initial
PSA
151, Gleason 9, 4 small mets to pelvis, spine, tailbone) had an appointment today, and his MO indicated that he would like to proceed with doublet therapy. I wasn't aware he would be a candidate for this treatment given his mets. Curious to hear others input on this.
SKKALH528
in
Advanced Prostate Cancer
10 days ago
Rising ALP and declining PSA
After starting I have declining
PSA
but dramatically rising ALP. Any thoughts on what this means? Thanks all.
After starting I have declining
PSA
but dramatically rising ALP. Any thoughts on what this means? Thanks all.
jersy
in
Advanced Prostate Cancer
4 months ago
Xtandi/Orgovyx Combo & Heart Rate
I am oligometastatic - one lymph node - and
PSA
is 0.07 with testosterone at 9.63. I am not castrate resistant. I was wondering if anyone else has experienced slowing heart rate (bradycardia) on this combo. (I also take Myrbetriq which may be contributing to a slower heart rate.) Thanks.
I am oligometastatic - one lymph node - and
PSA
is 0.07 with testosterone at 9.63. I am not castrate resistant. I was wondering if anyone else has experienced slowing heart rate (bradycardia) on this combo. (I also take Myrbetriq which may be contributing to a slower heart rate.) Thanks.
Explorer08
in
Advanced Prostate Cancer
2 months ago
Prostate Cancer Journey
I have been off treatment more than 50% of the last ten years Present
PSA
<.02
I have been off treatment more than 50% of the last ten years Present
PSA
<.02
thor17
in
Advanced Prostate Cancer
17 days ago
PSA dropping and % free ratio rising - why?
But I thought I might do another
PSA
test in the meantime but this time add the Free
psa
% ratio to the mix (we didn't do that in early Dec) So then my latest
PSA
test came back 4.74 and 12.7% free
psa
ratio. My original
PSA
in July was 8.1 and 7% free
psa
ratio ....
But I thought I might do another
PSA
test in the meantime but this time add the Free
psa
% ratio to the mix (we didn't do that in early Dec) So then my latest
PSA
test came back 4.74 and 12.7% free
psa
ratio. My original
PSA
in July was 8.1 and 7% free
psa
ratio ....
Mike58
in
Prostate Cancer Network
8 months ago
Expectations
Will my
PSA
automatically rise when the Eligard wears off? If and/or when it does, does that indicate a recurrence of the cancer somewhere? And if so, does that mean immediate ADT, a radiation refresher or a new work-up with pet/ct scans, etc.?
Will my
PSA
automatically rise when the Eligard wears off? If and/or when it does, does that indicate a recurrence of the cancer somewhere? And if so, does that mean immediate ADT, a radiation refresher or a new work-up with pet/ct scans, etc.?
Eadgbe
in
Advanced Prostate Cancer
4 months ago
Rapidly Rising PSA
without going into too much detail I was treated with SBRT for mets on my spine that showed up on a ga68 PSMA Pet scan in july 2021 I have been on Zoladex for 4 years and Xtandi for 20 months My
PSA
in Nov 2022 was 0.27 by Nov 2023 it was up to 2.40 and now Feb 2024 it is 5.70 Time for a PSMA
without going into too much detail I was treated with SBRT for mets on my spine that showed up on a ga68 PSMA Pet scan in july 2021 I have been on Zoladex for 4 years and Xtandi for 20 months My
PSA
in Nov 2022 was 0.27 by Nov 2023 it was up to 2.40 and now Feb 2024 it is 5.70 Time for a PSMA
Ian996
in
Advanced Prostate Cancer
6 months ago
Enlarged Lymph Nodes on MRI and CT
Gleason 7 (4+3)
PSA
6. Bone scan clear but lymphadenopathy in groin nodes (inguinal; iliac nodes). Does this mean spread? Being sent for a PET Scan Friday.
Gleason 7 (4+3)
PSA
6. Bone scan clear but lymphadenopathy in groin nodes (inguinal; iliac nodes). Does this mean spread? Being sent for a PET Scan Friday.
Blue1320
in
Prostate Cancer Network
4 months ago
Brand new here. Whopping high first PSA test
But I read these types of things do NOT elevate
PSA
that much. At the time I had no clue I was supposed to suspend certain activity before the blood draw. I've checked in with friends who have dealt with prostate CA issues and of course done online research.
But I read these types of things do NOT elevate
PSA
that much. At the time I had no clue I was supposed to suspend certain activity before the blood draw. I've checked in with friends who have dealt with prostate CA issues and of course done online research.
RazorSaw
in
Active Surveillance - Prostate Cancer
25 days ago
I owe you an update
My
PSA
was 9 at that time. I began ADT with Orgovyx in February, 2024. My
PSA
was 0.9 by late April. I had five high-dose SBRT treatments in April 29 to May 9. My Medical Oncologist reviewed my results in June and gave me a status of remission on June 7.
My
PSA
was 9 at that time. I began ADT with Orgovyx in February, 2024. My
PSA
was 0.9 by late April. I had five high-dose SBRT treatments in April 29 to May 9. My Medical Oncologist reviewed my results in June and gave me a status of remission on June 7.
Worked_the_World
in
Advanced Prostate Cancer
28 days ago
Testosterone was slowly recovering after stopping all meds 8/10/2023 then started dropping!
The plan was to use Xtandi mono therapy in order to maintain testosterone so hopefully hemoglobin would rise and
PSA
would decline.
The plan was to use Xtandi mono therapy in order to maintain testosterone so hopefully hemoglobin would rise and
PSA
would decline.
SViking
in
Advanced Prostate Cancer
5 months ago
Anyone treated with enzalutamide +cabazitaxel?
PSA
never got below 3. Latest CT bone scan shows progression in a few areas. RO will zap the progressing areas locally. MO suggested cabazitaxel (1st choice) or enzalutamide (discouraged because cancer is aggressive). Any data/experience that combined enzalutamide and cabazitaxel would be better?
PSA
never got below 3. Latest CT bone scan shows progression in a few areas. RO will zap the progressing areas locally. MO suggested cabazitaxel (1st choice) or enzalutamide (discouraged because cancer is aggressive). Any data/experience that combined enzalutamide and cabazitaxel would be better?
BeLikeWater
in
Advanced Prostate Cancer
2 months ago
Watching and waiting
My 78 year old husband was diagnosed with prostate cancer Gleason 8 two years ago. ( Urologist noticed a very slight rise in
psa
and located a tumor after dre. Biopsy showed cancerous cells in Only in three cores. Bone scan clean.
My 78 year old husband was diagnosed with prostate cancer Gleason 8 two years ago. ( Urologist noticed a very slight rise in
psa
and located a tumor after dre. Biopsy showed cancerous cells in Only in three cores. Bone scan clean.
Pastaking
in
Advanced Prostate Cancer
4 months ago
mHSPCa with undetectable PSA - chemo-only?
I have not been able to find any study on treatment for low-
PSA
metastatic disease.
I have not been able to find any study on treatment for low-
PSA
metastatic disease.
Purple-Bike
in
Advanced Prostate Cancer
7 months ago
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