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blood test to identify neuroendocrine cancer asap
ok I repost this mainly because the University of Trento is one hour from here and I got good friends there (working on CRISPR)…together with Dana-Farber they have developed a blood test to identify if there is an endocrine prostate cancer and the subtype https://medriva.com/cancer/a-breakthrough-in-prostate-cancer-treatment-new-blood-test-identifies-neuroendocrine-subtype
ok I repost this mainly because the University of Trento is one hour from here and I got good friends there (working on CRISPR)…together with Dana-Farber they have developed a blood test to identify if there is an endocrine prostate cancer and the subtype https://medriva.com/cancer/a-breakthrough-in-prostate-cancer-treatment-new-blood-test-identifies-neuroendocrine-subtype
Maxone73
in
Advanced Prostate Cancer
9 months ago
Father’s CRPCa Failed chemo (Cabazitaxel,Docetaxel) and Failed LU177
Father’s current Age: 78 At age 70, Diagnosed with Pca in 2015 after seeing initial PSA as ~ 270. 2015 - 2019 - BICALUTAMIDE - Failed 2019 - 2020 - Radiation- Ineffective 2020 Oct - 2021 October - Zytiga (Aberiterone) - Failed - PSA 98 2021 Dec - 2022 Apr - Docetaxel- Ineffective - PSA 120 2022
Father’s current Age: 78 At age 70, Diagnosed with Pca in 2015 after seeing initial PSA as ~ 270. 2015 - 2019 - BICALUTAMIDE - Failed 2019 - 2020 - Radiation- Ineffective 2020 Oct - 2021 October - Zytiga (Aberiterone) - Failed - PSA 98 2021 Dec - 2022 Apr - Docetaxel- Ineffective - PSA 120 2022
Vishwa1890
in
Advanced Prostate Cancer
8 months ago
Tough decision
I've been on AS for 5 years with Moffit had 3 biopsy's all gleason 6 except a second opinion on my first one 2 cores where changed to a 7. PSA has bounced around but highest was 6.43 this April last week 5.13. Because of my recent MRI shows growth on the lesion and possible extracasular extension. So
I've been on AS for 5 years with Moffit had 3 biopsy's all gleason 6 except a second opinion on my first one 2 cores where changed to a 7. PSA has bounced around but highest was 6.43 this April last week 5.13. Because of my recent MRI shows growth on the lesion and possible extracasular extension. So
twoodogs
in
Prostate Cancer Network
3 months ago
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At what point for scan ?
Hi. Currently just had # 4 chemo. Live in Canada so PSMA has never been done . Bone scan and CT scan. I'm wondering at what point it would be good to get a scan ( they already said it would probably be a CT scan as that's all we have in my province and eventually another bone scan which He has to fly
Hi. Currently just had # 4 chemo. Live in Canada so PSMA has never been done . Bone scan and CT scan. I'm wondering at what point it would be good to get a scan ( they already said it would probably be a CT scan as that's all we have in my province and eventually another bone scan which He has to fly
positive-thinking
in
Advanced Prostate Cancer
7 months ago
Chemo progress
PSA 139 @ DX1-2024 started Orgovyx and Nubeqa dropped PSA to 62.93. Started Chemo 1st infusion..PSA 23.3 2nd infusion..PSA 11.26 3rd infusion.. PSA 7.45 Just got my labs back for the 3rd infusion. Just feel disappointed as I was hoping for a larger drop and seemed to have stalled out. Does it look
PSA 139 @ DX1-2024 started Orgovyx and Nubeqa dropped PSA to 62.93. Started Chemo 1st infusion..PSA 23.3 2nd infusion..PSA 11.26 3rd infusion.. PSA 7.45 Just got my labs back for the 3rd infusion. Just feel disappointed as I was hoping for a larger drop and seemed to have stalled out. Does it look
APK3
in
Advanced Prostate Cancer
7 months ago
Blood test distinguishes neuroendocrine subtype of advanced prostate cancer
https://www.sciencedaily.com/releases/2024/01/240110120221.htm
https://www.sciencedaily.com/releases/2024/01/240110120221.htm
zeitgeistxx
in
Advanced Prostate Cancer
9 months ago
Triple therapy?
sorry, sorry, sorry. In the more detailed history in profile I got an important number wrong. Last PSA was 0.103, NOT 0.01! So sorry to have messed up!
sorry, sorry, sorry. In the more detailed history in profile I got an important number wrong. Last PSA was 0.103, NOT 0.01! So sorry to have messed up!
Ljrwife
in
Advanced Prostate Cancer
3 months ago
Metastatic prostate cancer in the lungs
Radical prostatectomy in 2003 with PSA of 3.9. PSA slowly rose to .07 in 2023. PET scan in May, 2023 found nodules in my lungs with the largest being 1.4 cm. Needle biopsy identified it as metastatic adenocarcinoma from prostatic origin. 5 sessions of 50Gy cyberknife treatments on the 1.4 cm nodule
Radical prostatectomy in 2003 with PSA of 3.9. PSA slowly rose to .07 in 2023. PET scan in May, 2023 found nodules in my lungs with the largest being 1.4 cm. Needle biopsy identified it as metastatic adenocarcinoma from prostatic origin. 5 sessions of 50Gy cyberknife treatments on the 1.4 cm nodule
S4survivor
in
Advanced Prostate Cancer
8 months ago
CAR T-Cell Therapy Demonstrates Promising Results for mCRPC
A total of 14 patients were treated between August 2019 and July 2022. The median patient age was 62 in dose level 1 (DL1), 70 for dose level 2 (DL2), and 69 for dose level 3 (DL3). The baseline prostate-specific antigen (PSA) ranged from 16.5 ng/mL to 235.3 ng/mL. Primary end points were safety and
A total of 14 patients were treated between August 2019 and July 2022. The median patient age was 62 in dose level 1 (DL1), 70 for dose level 2 (DL2), and 69 for dose level 3 (DL3). The baseline prostate-specific antigen (PSA) ranged from 16.5 ng/mL to 235.3 ng/mL. Primary end points were safety and
God_Loves_Me
in
Advanced Prostate Cancer
3 months ago
Lupron Injection denied by Medicare Advantage PPO plan
My husband will need Lupron injections monthly x4. Two before starting radiation, and 2 during radiation treatment. The insurance, Medicare Advantage PPO, denied it. Anyone successfully appealed the denial? Any suggestions from the group? I checked and Medicare part D covers Lupron for the treatment
My husband will need Lupron injections monthly x4. Two before starting radiation, and 2 during radiation treatment. The insurance, Medicare Advantage PPO, denied it. Anyone successfully appealed the denial? Any suggestions from the group? I checked and Medicare part D covers Lupron for the treatment
Inquisitive_one
in
Advanced Prostate Cancer
9 months ago
prostate met to esophagus
on the road for 9 years. Short story.. biopsy 4+3. Surg. Found in margins, pelvic lymphs. PSA 3 after. C11 found in lymph in chest. Chemo, then zytiga, Lupron, then 37 radiation, and meds then meds a year. Non detectable NED 7 years no meds tx 6 years. PSA started going up, slowly, bout 18 mo
on the road for 9 years. Short story.. biopsy 4+3. Surg. Found in margins, pelvic lymphs. PSA 3 after. C11 found in lymph in chest. Chemo, then zytiga, Lupron, then 37 radiation, and meds then meds a year. Non detectable NED 7 years no meds tx 6 years. PSA started going up, slowly, bout 18 mo
Kittenlover50
in
Advanced Prostate Cancer
8 months ago
Similar question to Ezzedine. PSA rising
March 19 I was diagnosed with Gleason 9 prostate cancer. PSA was 0.9 (it turns out I have a non secreting prostate. I had 37 sessions of EBRT and 3 years zoladex. Whilst under ADT and for 1 year after ADT conclusion my PSA was 0.01 (indecipherable) Then a year ago my PSA was 0.02, then 0.03 and last
March 19 I was diagnosed with Gleason 9 prostate cancer. PSA was 0.9 (it turns out I have a non secreting prostate. I had 37 sessions of EBRT and 3 years zoladex. Whilst under ADT and for 1 year after ADT conclusion my PSA was 0.01 (indecipherable) Then a year ago my PSA was 0.02, then 0.03 and last
arry4424
in
Prostate Cancer Network
7 months ago
PSA rise
2 months ago my PSA was 20. I have had extensive screening done prior to starting a clinical trial on Tuesday. My PSA has gone up to 367 since then. CT scan showed no significant change and I had bone scan yesterday. Onco says it may just be increased activity of existing cancer cells and not necessarily
2 months ago my PSA was 20. I have had extensive screening done prior to starting a clinical trial on Tuesday. My PSA has gone up to 367 since then. CT scan showed no significant change and I had bone scan yesterday. Onco says it may just be increased activity of existing cancer cells and not necessarily
konichiwa12
in
Advanced Prostate Cancer
8 months ago
Holding very low stable usPSA - 0.03X range for six years; no ADT, no chemo.
Eight years ago this month had RP after considerable investigation - nadir 0.050. Eleven months later had salvage RT; done at 0.10. Then after a year of pondering ADT and chemo, when my usPSA was back up to 0.10, I went to Europe for Ferrotran nano-MRI combined with Ga68 PSMA. The nanoMRI lite up
Eight years ago this month had RP after considerable investigation - nadir 0.050. Eleven months later had salvage RT; done at 0.10. Then after a year of pondering ADT and chemo, when my usPSA was back up to 0.10, I went to Europe for Ferrotran nano-MRI combined with Ga68 PSMA. The nanoMRI lite up
NanoMRI
in
Advanced Prostate Cancer
9 months ago
Rising psa
Is My cancer back? Ezzeddine Cherni Born: 10-09-1959. 65yo. Radical prostatectomy in 2011.at the age of 52 Gleason=7 PSA non detectable for 5 years :0.07. In 2016. 0.11. 2017: 0.17. IRM no local recurrence 2019: 0.22 IRM : no local recurrence. 2020: 0.18 2021: 0.38 IRM non local recurrence
Is My cancer back? Ezzeddine Cherni Born: 10-09-1959. 65yo. Radical prostatectomy in 2011.at the age of 52 Gleason=7 PSA non detectable for 5 years :0.07. In 2016. 0.11. 2017: 0.17. IRM no local recurrence 2019: 0.22 IRM : no local recurrence. 2020: 0.18 2021: 0.38 IRM non local recurrence
ezzeddine
in
Prostate Cancer Network
7 months ago
pluvicto
Finished my second treatment last week. My PSA went from 10 to22 after the first round. Today after the second round it dropped to 15. Anyone else have a jump after the first treatment and then continued to decline for the remaining treatments. I have failed chemo and xtanti and have read that
Finished my second treatment last week. My PSA went from 10 to22 after the first round. Today after the second round it dropped to 15. Anyone else have a jump after the first treatment and then continued to decline for the remaining treatments. I have failed chemo and xtanti and have read that
diatom
in
Advanced Prostate Cancer
3 months ago
More Evidence Linking ADT for PCa to Adverse Neurocognitive Effects -Meta-analysis shows increased risk of dementia, Parkinson's, depression
[i]As if we needed more reasons to dislike or avoid ADT, here is additional evidence of negative neurocognitive effects. This MedPage Today article will expecially be of special interest to those of us well into our "Golden Years" and on or considering ADT. [/i]
More Evidence Linking ADT for Prostate
[i]As if we needed more reasons to dislike or avoid ADT, here is additional evidence of negative neurocognitive effects. This MedPage Today article will expecially be of special interest to those of us well into our "Golden Years" and on or considering ADT. [/i]
More Evidence Linking ADT for Prostate
cujoe
in
Fight Prostate Cancer
9 months ago
Anyone else suffering arm pains in conjunction with ADT hot flashes?
Ever since commencing ADT (Decapeptyl 11.5mg) following recurrent PCa in 2022 I've been getting muscle pain in both arms. It always commences simultaneously with the onset of hot flashes. The pain courses down both arms from the shoulder to the backs of my hands. It's not too severe and each bout only
Ever since commencing ADT (Decapeptyl 11.5mg) following recurrent PCa in 2022 I've been getting muscle pain in both arms. It always commences simultaneously with the onset of hot flashes. The pain courses down both arms from the shoulder to the backs of my hands. It's not too severe and each bout only
LeakyLad
in
Advanced Prostate Cancer
3 months ago
given a choice about duration of ADT
Tall Allen and others. Clean PSMA, , 3+4, 3+4, and 4+3., biopsy. 77yrs old, hit gym daily but have significant side effects of lupron.. Being treated at Comprensive cancer center. Plan was one year of Lupron. After five SBRT, and nine months on adt, my doc is willing to let me terminate my Lupron
Tall Allen and others. Clean PSMA, , 3+4, 3+4, and 4+3., biopsy. 77yrs old, hit gym daily but have significant side effects of lupron.. Being treated at Comprensive cancer center. Plan was one year of Lupron. After five SBRT, and nine months on adt, my doc is willing to let me terminate my Lupron
Photographerhere
in
Prostate Cancer Network
9 months ago
Help me juggle SOC and my anxiety
I have just finish this May 18 months of Zoladex and had RT (VMRT 20x3Gy prostate and SV only) for localised G9 (PSMA no spread no SV involvement) after PSA was 8 following failed HIFU for G7) since 3 months after RT my PSA consistently 0.01 when on the HT. I now find myself MORE anxious as I deal
I have just finish this May 18 months of Zoladex and had RT (VMRT 20x3Gy prostate and SV only) for localised G9 (PSMA no spread no SV involvement) after PSA was 8 following failed HIFU for G7) since 3 months after RT my PSA consistently 0.01 when on the HT. I now find myself MORE anxious as I deal
SimMartin
in
Advanced Prostate Cancer
3 months ago
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