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Citicoline: "patients treated with citicoline experienced a significant worsening 45 days after the medication was discontinued". Updated.
This statement appears in a review that was published here: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10548481/ It is attributed to a study published in a book on citicoline in 1985. I've been unable to locate a copy of this book either online, for sale or to borrow from a library. Book: Zappia
This statement appears in a review that was published here: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10548481/ It is attributed to a study published in a book on citicoline in 1985. I've been unable to locate a copy of this book either online, for sale or to borrow from a library. Book: Zappia
park_bear
in
Cure Parkinson's
4 months ago
Lack of pain meds
Hi all.My Gp just said she will increase my Gabapentin but I've to stop the morphine liquid. I'm the last month I have stopped Tramadol and cocodamol. Naturally my pain has seriously increased. I've to reduce the morphine from today. Can anyone see the wisdom in this cos I sure dontðŸ˜. I'm currently
Hi all.My Gp just said she will increase my Gabapentin but I've to stop the morphine liquid. I'm the last month I have stopped Tramadol and cocodamol. Naturally my pain has seriously increased. I've to reduce the morphine from today. Can anyone see the wisdom in this cos I sure dontðŸ˜. I'm currently
Smilesalot
in
Fibromyalgia Action UK
4 months ago
accidental overdose,
has anyone taken too many sotalol, I felt unwell with extreme heat ,legs like jelly and breathless, Later realised I had taken 4x80 mg of sotalol instead of 2. Can anyone advise wether these are the symptoms of taking too much or could have been something else entirely. Looking forward to some helpful
has anyone taken too many sotalol, I felt unwell with extreme heat ,legs like jelly and breathless, Later realised I had taken 4x80 mg of sotalol instead of 2. Can anyone advise wether these are the symptoms of taking too much or could have been something else entirely. Looking forward to some helpful
Hatten28
in
Atrial Fibrillation Support
4 months ago
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peripheral neuropathy caused by Folfox chemotherapy
Stage 3 colon cancer Resection 1 1/2 yr ago followed by 12 cycles of Folfox over 6 months Peripheral Neuropathy started in the first couple of cycles and following cycle 7 had to stop oxaliplatin component which causes peripheral neuropathy in some patients It has been 1 year since my last cycle and
Stage 3 colon cancer Resection 1 1/2 yr ago followed by 12 cycles of Folfox over 6 months Peripheral Neuropathy started in the first couple of cycles and following cycle 7 had to stop oxaliplatin component which causes peripheral neuropathy in some patients It has been 1 year since my last cycle and
WalterDisney
in
Neuropathy Support
4 months ago
The next generation of medical researchers …
Thought I would share this personal story about how I have seen hope for the future of medical research firsthand and perhaps the understanding various disease pathways. My granddaughter will be graduating in May ‘24 and has been involved with biological research over the last three years at the university
Thought I would share this personal story about how I have seen hope for the future of medical research firsthand and perhaps the understanding various disease pathways. My granddaughter will be graduating in May ‘24 and has been involved with biological research over the last three years at the university
Mgtd
in
Advanced Prostate Cancer
4 months ago
Mike C
Have been on 10 mg bisoprolol for12 years (and doing fine )for parox af which moved to persist 120 days ago, cardìo changed me to 2 x40 sotalol with a view to maybe a DC cardioversìon. After 24 hrs from last bisopr I tookfirst 40mg Sotalol and few hrs later lots ?pvc s? and diastolic at 105 = unusual
Have been on 10 mg bisoprolol for12 years (and doing fine )for parox af which moved to persist 120 days ago, cardìo changed me to 2 x40 sotalol with a view to maybe a DC cardioversìon. After 24 hrs from last bisopr I tookfirst 40mg Sotalol and few hrs later lots ?pvc s? and diastolic at 105 = unusual
magendomike
in
Atrial Fibrillation Support
4 months ago
Ropinerole
I've been on Gabapentin and Ropinerole for 25 years, and finally got off due to the terrible effects of augmentation. I've been on Lyrica now for about 6 months, and other than not having daytime symptoms, my nights have been worse than ever. I was at a motel recently, and took one Ropinerole because
I've been on Gabapentin and Ropinerole for 25 years, and finally got off due to the terrible effects of augmentation. I've been on Lyrica now for about 6 months, and other than not having daytime symptoms, my nights have been worse than ever. I was at a motel recently, and took one Ropinerole because
Marzipana
in
Restless Legs Syndrome
4 months ago
Antidepressants
Hi all, Increased anxiety has become one of my worst symptoms of B12 deficiency and (possible*) PA. I’m on 4 weekly B12 injections (Hydrocobalamin 1mg) on the NHS but I’ve not noticed any improvements so far. I’ve had the 6 loading doses and 2 further injections so far. I’m taking D3/K2 (3000iu/100ug
Hi all, Increased anxiety has become one of my worst symptoms of B12 deficiency and (possible*) PA. I’m on 4 weekly B12 injections (Hydrocobalamin 1mg) on the NHS but I’ve not noticed any improvements so far. I’ve had the 6 loading doses and 2 further injections so far. I’m taking D3/K2 (3000iu/100ug
Pa234aw
in
Pernicious Anaemia Society
4 months ago
Repeat Lutetium/ Pluvicto treatment
Hello all, I am just curious if anyone has experience doing additional lutetium treatments. I did three lutetium treatments from September 2021 to January 2022. My Denver oncologist is concerned about bone marrow toxicity , but he does not have enough experience with this treatment to say for sure.
Hello all, I am just curious if anyone has experience doing additional lutetium treatments. I did three lutetium treatments from September 2021 to January 2022. My Denver oncologist is concerned about bone marrow toxicity , but he does not have enough experience with this treatment to say for sure.
Eugmn
in
Advanced Prostate Cancer
4 months ago
Still no diagnosis and feeling dosheartened
I felt so certain I had PA but my gp has told me both tests done were normal. My B12 has been between 190 and 246 and that was with supplements but it has always dropped down over the past few years. I’ve been given a 3 monthly B12 and had my first dose but my GP has declined me loading doses even though
I felt so certain I had PA but my gp has told me both tests done were normal. My B12 has been between 190 and 246 and that was with supplements but it has always dropped down over the past few years. I’ve been given a 3 monthly B12 and had my first dose but my GP has declined me loading doses even though
Curiouselephant
in
Pernicious Anaemia Society
4 months ago
My Labs are back- recommendations pretty please.
Quick summary- RLS for last 20yrs but self endured with no meds until Covid hit and exacerbated symptoms x100. Went to sleep MD and he just started with scripting meds….Gabapentin, Pregabalin, Busibar, Doxepin, Requip, Lunesta. None of these really worked…Requip kinda did but then it did not. So
Quick summary- RLS for last 20yrs but self endured with no meds until Covid hit and exacerbated symptoms x100. Went to sleep MD and he just started with scripting meds….Gabapentin, Pregabalin, Busibar, Doxepin, Requip, Lunesta. None of these really worked…Requip kinda did but then it did not. So
Ddski5
in
Restless Legs Syndrome
4 months ago
Neuropathy in feet, stopping Cymbalta - try more natural?
I'd like to get your opinion if you have been on something like Cymbalta (Duloxetine) and came off to do more natural methods. I'd like to stop the Cymbalta that I've been using for years to help with the neuropathy in my feet and look at other way to see if I can control it vs using an SNRI. I've
I'd like to get your opinion if you have been on something like Cymbalta (Duloxetine) and came off to do more natural methods. I'd like to stop the Cymbalta that I've been using for years to help with the neuropathy in my feet and look at other way to see if I can control it vs using an SNRI. I've
Shomacco
in
Neuropathy Support
4 months ago
What I use for my neuropathy
Certain alt treatment I am taking has temporary neuropathy as a listed side effect treatable with daily dosage of Benfotiamine, R-Lipoic-Acid- and optional use of Acetyl-L-Carnitine all suppliments and to add to this list I will be adding Lions Mane mushroom , having a neuroregenerative effect. also
Certain alt treatment I am taking has temporary neuropathy as a listed side effect treatable with daily dosage of Benfotiamine, R-Lipoic-Acid- and optional use of Acetyl-L-Carnitine all suppliments and to add to this list I will be adding Lions Mane mushroom , having a neuroregenerative effect. also
85745
in
Advanced Prostate Cancer
5 months ago
foot pain
Does anyone have horrendous pain in the ball of their feet and sometimes in toes. Sometimes on one or the other and sometimes on both? It’s affecting me walking :(
Does anyone have horrendous pain in the ball of their feet and sometimes in toes. Sometimes on one or the other and sometimes on both? It’s affecting me walking :(
Merc19
in
Fibromyalgia Action UK
5 months ago
SI - opinion valued
Have been SI sub cut EOD since late July 2023, (due to neuropathy and have a formal diagnosis from neurologist of Short Fibre Neuropathy). I had been using Panpharma but due to supply issues have secured a delivery of Pasco Hydoxocobalamin instead. So my question is: Shall I carry on EOD with the
Have been SI sub cut EOD since late July 2023, (due to neuropathy and have a formal diagnosis from neurologist of Short Fibre Neuropathy). I had been using Panpharma but due to supply issues have secured a delivery of Pasco Hydoxocobalamin instead. So my question is: Shall I carry on EOD with the
JanCymru
in
Pernicious Anaemia Society
5 months ago
Peripheral neuropathy
Just researching vitamin K2 and found this..... Peripheral neuropathy (PN) Diabetic peripheral neuropathy is a frequent and severe complication of diabetes. A recent study aimed to evaluate factors associated with sensitive diabetic neuropathy in Type 2 Diabetes, and, in particular, dephospho-uncarboxylated
Just researching vitamin K2 and found this..... Peripheral neuropathy (PN) Diabetic peripheral neuropathy is a frequent and severe complication of diabetes. A recent study aimed to evaluate factors associated with sensitive diabetic neuropathy in Type 2 Diabetes, and, in particular, dephospho-uncarboxylated
tomdickharry
in
Pernicious Anaemia Society
5 months ago
Transitioning to Gabapentin Enacarbil
I need some advice when it comes to starting Horizant while moving away from Pramipexole. I've been on Pram for about 12 years and although it still works generally, it's getting less an less effective. So it's time to move on. Gabapentin Enacarbil (Horizant) is what I'm moving to. My question
I need some advice when it comes to starting Horizant while moving away from Pramipexole. I've been on Pram for about 12 years and although it still works generally, it's getting less an less effective. So it's time to move on. Gabapentin Enacarbil (Horizant) is what I'm moving to. My question
grizzly99
in
Restless Legs Syndrome
5 months ago
peripheral neuropathy
Hello, I am on R and V as a second line treatment having relapsed after a short number of months following two years of I and V on the FLAIR trial. I am having problems with peripheral neuropathy pains which medications aren’t really helping with……and the cold weather definitely doesn’t help! I am
Hello, I am on R and V as a second line treatment having relapsed after a short number of months following two years of I and V on the FLAIR trial. I am having problems with peripheral neuropathy pains which medications aren’t really helping with……and the cold weather definitely doesn’t help! I am
hector66
in
CLL Support
5 months ago
Something to celebrate
I just needed somewhere to share my elation!! I've been having regular flare ups of both lupus and rheumatoid even though I'm on the highest doses of medication I can be on. Everytime I've been for bloods everything has pretty much come back within normal range. I've been experiencing altered sensations
I just needed somewhere to share my elation!! I've been having regular flare ups of both lupus and rheumatoid even though I'm on the highest doses of medication I can be on. Everytime I've been for bloods everything has pretty much come back within normal range. I've been experiencing altered sensations
Sunshine634
in
LUPUS UK
5 months ago
Thank you everybody - part 2
Part 1 - https://healthunlocked.com/advanced-prostate-cancer/posts/150427052/thank-you-everybody So i drive 30 minutes to get to the clinic, spend 30 minutes, at the clinic, drive 30 minutes to get home. I see the NP (who confers with the MO as needed before and after my visits). 1. They don't
Part 1 - https://healthunlocked.com/advanced-prostate-cancer/posts/150427052/thank-you-everybody So i drive 30 minutes to get to the clinic, spend 30 minutes, at the clinic, drive 30 minutes to get home. I see the NP (who confers with the MO as needed before and after my visits). 1. They don't
skiingfiend
in
Advanced Prostate Cancer
5 months ago
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