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Paroxysmal atrial fibrillation
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Know your Biomarker … Know Your Mutation
KRAS mutation in colorectal cancer is an abnormal change in the KRAS gene, which is involved in controlling cell growth and survival. 40% of CRC has a KRAS mutation. There are more than 25 ongoing clinical trials studying treatments for KRAS-mutated colorectal cancer. Learn more about the KRAS biomarker
KRAS mutation in colorectal cancer is an abnormal change in the KRAS gene, which is involved in controlling cell growth and survival. 40% of CRC has a KRAS mutation. There are more than 25 ongoing clinical trials studying treatments for KRAS-mutated colorectal cancer. Learn more about the KRAS biomarker
GCCA-Survivor
Administrator
in
Colon Cancer Connected
7 months ago
Difficulty turning over in bed
A few years ago l asked if any of you had trouble turning over in bed and got a lot of responses- some compared it to feeling like a beached whale ! Recently l had a shoulder replacement which made it even worse for me so my son came to my rescue. It has helped so much that l thought l would share it
A few years ago l asked if any of you had trouble turning over in bed and got a lot of responses- some compared it to feeling like a beached whale ! Recently l had a shoulder replacement which made it even worse for me so my son came to my rescue. It has helped so much that l thought l would share it
Trulyscrumpious
in
PMRGCAuk
1 year ago
Cancelled Again
Well here I go again, another cancellation, another wait. I have continual AF for just coming up to two years. I’m on 10mg of Bisoprolol and 62.5 digoxin, plus Apixaban. First appointment with Cardio, told to lose weight and get on with it, no medication, oh ok. Went to GP who gave medication and
Well here I go again, another cancellation, another wait. I have continual AF for just coming up to two years. I’m on 10mg of Bisoprolol and 62.5 digoxin, plus Apixaban. First appointment with Cardio, told to lose weight and get on with it, no medication, oh ok. Went to GP who gave medication and
Carnationmac
in
AF Association
1 year ago
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Periodic episodes of fluctuating tachycardia while in AFib.
Never had any heart problems until early 2020. I'm a rather robust yet strong guy , late 40s. I suspect COVID may have had something to do with it. Never vaccinated either..went to e.r after having AFib for 16 hrs. Was blacking out at work. Thought I was going to die. Spent 2 days in hospital. Echocardiogram
Never had any heart problems until early 2020. I'm a rather robust yet strong guy , late 40s. I suspect COVID may have had something to do with it. Never vaccinated either..went to e.r after having AFib for 16 hrs. Was blacking out at work. Thought I was going to die. Spent 2 days in hospital. Echocardiogram
Arrythimicaneurysm
in
Arrhythmia Alliance
1 year ago
Multi-Drug Combo May Be Best Against Prostate Cancer...I thought it was a known fact already!
"Combining two or three testosterone-blocking drugs prevents the spread of prostate cancer better than just a single medication, a new clinical trial has found." Dr Aggrawal again! https://www.usnews.com/news/health-news/articles/2024-01-25/multi-drug-combo-may-be-best-against-prostate-cancer
"Combining two or three testosterone-blocking drugs prevents the spread of prostate cancer better than just a single medication, a new clinical trial has found." Dr Aggrawal again! https://www.usnews.com/news/health-news/articles/2024-01-25/multi-drug-combo-may-be-best-against-prostate-cancer
Maxone73
in
Advanced Prostate Cancer
7 months ago
Apixaban and Ablation
Hi everyone, I am currently on a very long waiting list for Ablation. I have PAF with very symptomatic episodes lasting 30 hours approximately every 4 months. I take apixaban and sotalol but do not want to up the dose as suggested by my EP (I currently take 40mg three times daily).At the last visit to
Hi everyone, I am currently on a very long waiting list for Ablation. I have PAF with very symptomatic episodes lasting 30 hours approximately every 4 months. I take apixaban and sotalol but do not want to up the dose as suggested by my EP (I currently take 40mg three times daily).At the last visit to
Karendeena
in
AF Association
1 year ago
Does it indicate failure of another clinical trial
Annovis blames ‘data cleaning’ efforts for delaying phase 3 Parkinson’s readout https://www.fiercebiotech.com/biotech/annovis-blames-data-cleaning-efforts-delaying-phase-3-parkinsons-readout
Annovis blames ‘data cleaning’ efforts for delaying phase 3 Parkinson’s readout https://www.fiercebiotech.com/biotech/annovis-blames-data-cleaning-efforts-delaying-phase-3-parkinsons-readout
Farooqji
in
Cure Parkinson's
7 months ago
Clinical Trials
Has anyone participated in ANY Clinical Trials?? Which ones and have they helped at all???
Has anyone participated in ANY Clinical Trials?? Which ones and have they helped at all???
smv123
in
Cure Parkinson's
7 months ago
Vitamin D and Dementia
Vitamin D is a topic that gets a regular airing on this forum. In the context of CLL, here is a good place to review past posts https://healthunlocked.com/cllsupport/posts/149126536/recent-research-report?responses=149129259 (reply by Lankisterguy). Personally, the idea of dying with CLL just doesn't
Vitamin D is a topic that gets a regular airing on this forum. In the context of CLL, here is a good place to review past posts https://healthunlocked.com/cllsupport/posts/149126536/recent-research-report?responses=149129259 (reply by Lankisterguy). Personally, the idea of dying with CLL just doesn't
bennevisplace
in
CLL Support
7 months ago
Easy-to-use inhaled levodopa system readying request for US approval
That’s according to results from a company-sponsored clinical trial (NCT06037590) comparing the pharmacological properties of Levodopa Cyclops against those of Inbrija, an approved inhaled powder formulation of levodopa developed by Acorda Therapeutics. “This randomized cross-over trial of Levodopa
That’s according to results from a company-sponsored clinical trial (NCT06037590) comparing the pharmacological properties of Levodopa Cyclops against those of Inbrija, an approved inhaled powder formulation of levodopa developed by Acorda Therapeutics. “This randomized cross-over trial of Levodopa
Farooqji
in
Cure Parkinson's
7 months ago
clinical trial: ATR inhibitor for ATM mutated solid tumors
in vivo and in vitro studies suggest that ATR inhibitors work better than PARP inhibitors for people with ATM gene mutations…but together they may work even better I hope to find more data about this clinical trial https://www.biospace.com/article/releases/aprea-therapeutics-announces-dosing-of-first-patient-in-phase
in vivo and in vitro studies suggest that ATR inhibitors work better than PARP inhibitors for people with ATM gene mutations…but together they may work even better I hope to find more data about this clinical trial https://www.biospace.com/article/releases/aprea-therapeutics-announces-dosing-of-first-patient-in-phase
Maxone73
in
Advanced Prostate Cancer
7 months ago
New Thyroid Results - Conversion Issue?
Hi, After an emotional Thyroid rollercoaster these past couple years (post partial thyroidectomy 12/2/21 in combination with an Endo who doesn't believe in compounded medication), I finally seem to be settling into a medication and dose that works okay. I'd have to say that I'm still a bit tired and
Hi, After an emotional Thyroid rollercoaster these past couple years (post partial thyroidectomy 12/2/21 in combination with an Endo who doesn't believe in compounded medication), I finally seem to be settling into a medication and dose that works okay. I'd have to say that I'm still a bit tired and
KarmaMaya
in
Thyroid UK
7 months ago
Current SUPERNOVA Clinical Trial for Reformulated EVUSHELD for preventing COVID-19 infection for immune-impaired individuals
A Phase II sub-study of SUPERNOVA clinical trial (2023) is currently operating to test the efficacy and safety of AZD3152 as a component of a reformulated version of EVUSHELD mAbs prophylaxis for immune-impaired individuals who cannot mount antibody responses to COVID-19 vaccines. Study Understanding
A Phase II sub-study of SUPERNOVA clinical trial (2023) is currently operating to test the efficacy and safety of AZD3152 as a component of a reformulated version of EVUSHELD mAbs prophylaxis for immune-impaired individuals who cannot mount antibody responses to COVID-19 vaccines. Study Understanding
Classicaljazz
in
CLL Support
7 months ago
need some guidance, feeling desperate..
My husband has advanced, Stage IV castration resistant prostate cancer. When he was diagnosed in May 2022 his PSA was 4700, he has widespread bone metastases. He stopped responding to Docetaxel, Pluvicto and is now not responding to Cabazitaxel, his PSA is now over 700. He is feeling good, no pain
My husband has advanced, Stage IV castration resistant prostate cancer. When he was diagnosed in May 2022 his PSA was 4700, he has widespread bone metastases. He stopped responding to Docetaxel, Pluvicto and is now not responding to Cabazitaxel, his PSA is now over 700. He is feeling good, no pain
Kiki27
in
Advanced Prostate Cancer
7 months ago
Taste Issues and finger neuropathy on Xtandi( enzalutamide) ?
In order to participate in a clinical trial (FOR46 at UCSF) I had to switch from Nubeqa (darolutamide) to enzalutamide. Previously on abiraterone. Did really well on both medications. Now 4 months on enzalutamide and my 5th research infusion, I'm experiencing some side effects. Trying to determine
In order to participate in a clinical trial (FOR46 at UCSF) I had to switch from Nubeqa (darolutamide) to enzalutamide. Previously on abiraterone. Did really well on both medications. Now 4 months on enzalutamide and my 5th research infusion, I'm experiencing some side effects. Trying to determine
bandgeek
in
Advanced Prostate Cancer
7 months ago
Digoxin fears
Hello,am new to this forum, at mo feeling I am in the minority taking digoxin really feeling anxious about having to take prob have read Mr Google far too much I had an episode of AF was taken into a&e tried to right it by high dose of bisoprolol but had no affect, after 20 hrs erratic beats 140 to
Hello,am new to this forum, at mo feeling I am in the minority taking digoxin really feeling anxious about having to take prob have read Mr Google far too much I had an episode of AF was taken into a&e tried to right it by high dose of bisoprolol but had no affect, after 20 hrs erratic beats 140 to
Ssuegos
in
AF Association
1 year ago
What to do?
Hi All, I lost a load of weight last year doing a keto diet. Subsequently I didn't have AFib for 18 months. I have Paroxysmal AFib and usually only have 1 AFib a year. I always cardiovert with Flecanide. My Chadvac is 0. However, this year I've put more weight on and blood pressure has risen and I've
Hi All, I lost a load of weight last year doing a keto diet. Subsequently I didn't have AFib for 18 months. I have Paroxysmal AFib and usually only have 1 AFib a year. I always cardiovert with Flecanide. My Chadvac is 0. However, this year I've put more weight on and blood pressure has risen and I've
CJ1971
in
AF Association
1 year ago
Randomised clinical trial - prophylactic radiation therapy to asymptomatic bone metastases improved survival
Prophylactic Radiation Therapy Versus Standard of Care for Patients With High-Risk Asymptomatic Bone Metastases: A Multicenter, Randomized Phase II Clinical Trial Authors: Erin F. Gillespie, MD, MPH https://orcid.org/0000-0002-1386-1542 gillespe@mskcc.org, Joanna C. Yang, MD, MPH, Noah J. Mathis, BA
Prophylactic Radiation Therapy Versus Standard of Care for Patients With High-Risk Asymptomatic Bone Metastases: A Multicenter, Randomized Phase II Clinical Trial Authors: Erin F. Gillespie, MD, MPH https://orcid.org/0000-0002-1386-1542 gillespe@mskcc.org, Joanna C. Yang, MD, MPH, Noah J. Mathis, BA
Graham49
in
Advanced Prostate Cancer
7 months ago
Flecainide stopped working
I have been on Flecainide for years & my AF well controlled. Now it has started to cause other arrhythmias so I have to stop it This happened a few years ago & as soon as it was stopped my AF occurred regularly & made me feel very unwell I was able then to restart it but this time it’s not possible
I have been on Flecainide for years & my AF well controlled. Now it has started to cause other arrhythmias so I have to stop it This happened a few years ago & as soon as it was stopped my AF occurred regularly & made me feel very unwell I was able then to restart it but this time it’s not possible
Koladog
in
Atrial Fibrillation Support
1 year ago
Acalabrutinib and Skin Cancers
I began taking Acalabrutinib three years ago as a participant in a clinical trial. I have enjoyed excellent success. However, recently I began breaking out in skin cancer lesions on various parts of the body. Particularly on my legs, ankles and feet. I have been prone to sun damaged skin converting
I began taking Acalabrutinib three years ago as a participant in a clinical trial. I have enjoyed excellent success. However, recently I began breaking out in skin cancer lesions on various parts of the body. Particularly on my legs, ankles and feet. I have been prone to sun damaged skin converting
spanish36
in
CLL Support
7 months ago
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