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PSA uptick
Quick background, my dad was diagnosed with metastatic PCa in 2018. Initially treated with docetaxel + ADT. His PSA has been at/near undetected (<0.01-0.02) for several years, but recently there has been an uptick to 0.08 (similar on a recheck, so not lab error). Obviously still low-level, but concerning
Quick background, my dad was diagnosed with metastatic PCa in 2018. Initially treated with docetaxel + ADT. His PSA has been at/near undetected (<0.01-0.02) for several years, but recently there has been an uptick to 0.08 (similar on a recheck, so not lab error). Obviously still low-level, but concerning
mediocra
in
Advanced Prostate Cancer
5 months ago
Medically induced menopause at 24
So I had surgery in July my pain ramped up post surgery and I'm not in excruciating pain daily some days bed bound I work and had 37 days of since km worried about my job they seem OK but its a worry still. I've exhausted alot of options eg. Pain relief and dienogest, doubling my pill for hormones ect
So I had surgery in July my pain ramped up post surgery and I'm not in excruciating pain daily some days bed bound I work and had 37 days of since km worried about my job they seem OK but its a worry still. I've exhausted alot of options eg. Pain relief and dienogest, doubling my pill for hormones ect
En89
in
Endometriosis UK
8 months ago
Zoladex experience
Just wanted to hear other people's experiences on Zoladex if possible because I don't know if my symptoms are all in my head or I'm just being made to feel that way by the consultant. Who's only advice every time I go for a review every couple of months day just keep going with it a little bit longer
Just wanted to hear other people's experiences on Zoladex if possible because I don't know if my symptoms are all in my head or I'm just being made to feel that way by the consultant. Who's only advice every time I go for a review every couple of months day just keep going with it a little bit longer
x_b_x
in
Endometriosis UK
5 months ago
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Reason for ADT
Why is ADT used after SBRT? If radiation kills the cancer or makes it impossible to reproduce, then why do some doctors recommend ADT?
Why is ADT used after SBRT? If radiation kills the cancer or makes it impossible to reproduce, then why do some doctors recommend ADT?
Victor615
in
Prostate Cancer Network
5 months ago
biochemical recurrence after RP. +post leukemia
RP surgery 3/2020. Psa levels stable less than .01 for two years. 6/23 thru 12/23 levels have been .18 to .41. Complication 8/22 diagnosed with AML Leukemia. 5 rounds of chemo and a bone marrow transplant on 1/5/2023. Leukemia is now in complete remission, my blood dna is my donor’s - 40 year
RP surgery 3/2020. Psa levels stable less than .01 for two years. 6/23 thru 12/23 levels have been .18 to .41. Complication 8/22 diagnosed with AML Leukemia. 5 rounds of chemo and a bone marrow transplant on 1/5/2023. Leukemia is now in complete remission, my blood dna is my donor’s - 40 year
junkwerc
in
Prostate Cancer Network
5 months ago
6 months after MRI Guided SBRT at MSK
After a year and a half of Active Surveillance, my cancer progressed to GL 4+3 and I decided to have MRI Guided SBRT in August at Memorial Sloan Kettering in NYC under the care of Dr. Sean McBride. I had 5 sessions over 10 days and each lasted about an hour. The entire team at MSK was wonderful and
After a year and a half of Active Surveillance, my cancer progressed to GL 4+3 and I decided to have MRI Guided SBRT in August at Memorial Sloan Kettering in NYC under the care of Dr. Sean McBride. I had 5 sessions over 10 days and each lasted about an hour. The entire team at MSK was wonderful and
rosenjpj
in
Advanced Prostate Cancer
5 months ago
EBRT - Is it the right thing and what to expect?
After DX in November 2018 with Stage IV and Gleason of 5+4 and 4+5, and 5 years of ADT of Lupron (then Orgovyx), prednisone 5mg, and Zytiga 250mg with low fat breakfast, my PSA stayed stable at 0.4 or 0.5. At end of 2013, PSA started rising to latest value of 0.84. Had PSMA PET Scan March 5, 2024
After DX in November 2018 with Stage IV and Gleason of 5+4 and 4+5, and 5 years of ADT of Lupron (then Orgovyx), prednisone 5mg, and Zytiga 250mg with low fat breakfast, my PSA stayed stable at 0.4 or 0.5. At end of 2013, PSA started rising to latest value of 0.84. Had PSMA PET Scan March 5, 2024
JazzMan42
in
Advanced Prostate Cancer
4 months ago
A Clinical Trial saved my Life ..12 years a Survivor of Advanced Metastatic Prostate Cancer, Stage 4.
When Alfred Samuels was diagnosed with advanced prostate cancer in 2012, it felt as if his world had fallen apart overnight. Doctors said surgery wasn’t an option for him because the cancer had spread beyond his prostate, and he started to lose hope. But then he joined a clinical trial and began treatment
When Alfred Samuels was diagnosed with advanced prostate cancer in 2012, it felt as if his world had fallen apart overnight. Doctors said surgery wasn’t an option for him because the cancer had spread beyond his prostate, and he started to lose hope. But then he joined a clinical trial and began treatment
alsam
in
Understanding Clinical Trials
5 months ago
Help Needed! Have I got Pernicious Anaemia?
I hope this isn't too long and/or too boring. I suspect I have PA but as with a lot of people here, no-one seems to take B12 deficiency seriously. I also have hypothyroidism so as my symptoms got increasingly worse over the past few years, I blamed my thyroid - the two conditions have many symptoms
I hope this isn't too long and/or too boring. I suspect I have PA but as with a lot of people here, no-one seems to take B12 deficiency seriously. I also have hypothyroidism so as my symptoms got increasingly worse over the past few years, I blamed my thyroid - the two conditions have many symptoms
Grannypants
in
Pernicious Anaemia Society
5 months ago
Pirtobrutinib triple trial Cycle 7 update
Hi, ya'll! I'm now finishing up Cycle 8 of: [i]
Time-limited Triplet Combination of Pirtobrutinib, Venetoclax, and Obinutuzumab for Patients With Treatment-naïve Chronic Lymphocytic Leukemia (CLL) or Richter Transformation (RT)
[/i] at M.D. Anderson in Houston, TX. https://clinicaltrials.gov
Hi, ya'll! I'm now finishing up Cycle 8 of: [i]
Time-limited Triplet Combination of Pirtobrutinib, Venetoclax, and Obinutuzumab for Patients With Treatment-naïve Chronic Lymphocytic Leukemia (CLL) or Richter Transformation (RT)
[/i] at M.D. Anderson in Houston, TX. https://clinicaltrials.gov
SeymourB
in
CLL Support
10 months ago
how often should you have a Dexa scan ?
I had one when I was first diagnosed with PMR about 6 years ago. Since then I have tapered down the pred but couldn’t get below 2 mgs until … I restarted HRT. I have now managed to taper to zero for the last 2 weeks and fingers crossed, I’m hoping that’s it ! Mindful it could always creep back of course
I had one when I was first diagnosed with PMR about 6 years ago. Since then I have tapered down the pred but couldn’t get below 2 mgs until … I restarted HRT. I have now managed to taper to zero for the last 2 weeks and fingers crossed, I’m hoping that’s it ! Mindful it could always creep back of course
Seekingasolution
in
PMRGCAuk
5 months ago
why docs don’t want to prescribe opioids for RLS….😔
With all the recent total panic by docs on not prescribing opioids, I thought I would just attach Andy Berkowski’s excellent piece on why we are often being refused opioids now and almost certainly in the future at least for sometime. You may well have read this article before Kakally Andy Berkowski
With all the recent total panic by docs on not prescribing opioids, I thought I would just attach Andy Berkowski’s excellent piece on why we are often being refused opioids now and almost certainly in the future at least for sometime. You may well have read this article before Kakally Andy Berkowski
Kakally
in
Restless Legs Syndrome
10 months ago
Slow colonic transit
I have been diagnosed with slow colonic transit after having all the usual bowel investigations. I have been suffering suffering from chronic constipation for several years. I have been taking Prucalopride for almost a month but unfortunately it has made no difference. My consultant has recommended
I have been diagnosed with slow colonic transit after having all the usual bowel investigations. I have been suffering suffering from chronic constipation for several years. I have been taking Prucalopride for almost a month but unfortunately it has made no difference. My consultant has recommended
Riccar24
in
IBS Network
10 months ago
Targeting Mets w SBRT- what’s your experience?
Have any of you guys had any luck targeting distant metastases with SBRT after your mets remained small or dormant while on ADT but after PSMA scans had showed more in number than olago (more than five mets)? My PSMA scan in January 2022 showed 10 scattered small mets so our area SBRT (Cyberknife) radiation
Have any of you guys had any luck targeting distant metastases with SBRT after your mets remained small or dormant while on ADT but after PSMA scans had showed more in number than olago (more than five mets)? My PSMA scan in January 2022 showed 10 scattered small mets so our area SBRT (Cyberknife) radiation
SeattleDan
in
Advanced Prostate Cancer
5 months ago
Zoladex & Tibolone
Hi, I have just started a 3month trial of Zoladex implant / injection and daily Tiblone. I was wondering if anyone else has tried this? I have been given a clearance of stage 3 and 4 endo but they are not sure if I have stage 1 or 2. Ive always struggled with IBS and painful periods which I went
Hi, I have just started a 3month trial of Zoladex implant / injection and daily Tiblone. I was wondering if anyone else has tried this? I have been given a clearance of stage 3 and 4 endo but they are not sure if I have stage 1 or 2. Ive always struggled with IBS and painful periods which I went
Loulabelle1709
in
Women's Health
5 months ago
Benefits of split dosing T4
I hearken back to my post a few months ago https://healthunlocked.com/thyroiduk/posts/149418197/high-morning-cortisol-and-t3 where I was struggling (and still am) to find a solution to the severe waking anxiety I have had to tolerate for years now. As I feel my adrenals are still playing a big part
I hearken back to my post a few months ago https://healthunlocked.com/thyroiduk/posts/149418197/high-morning-cortisol-and-t3 where I was struggling (and still am) to find a solution to the severe waking anxiety I have had to tolerate for years now. As I feel my adrenals are still playing a big part
Jefner
in
Thyroid UK
5 months ago
Results
Hello everyone. Firstly I want to say a big thanks to everyone that helped me understand my mum's results and situation. I also got my wires crossed and gave some wrong info. My mum did have a test before they prescribed 25mg, TSH 8.58. They said as she was 'borderline' they would try levo before considering
Hello everyone. Firstly I want to say a big thanks to everyone that helped me understand my mum's results and situation. I also got my wires crossed and gave some wrong info. My mum did have a test before they prescribed 25mg, TSH 8.58. They said as she was 'borderline' they would try levo before considering
RedOne1
in
Thyroid UK
5 months ago
Getting to the root of my anxiety
I am 57 and I was considered in menopause at 52 years old, however I went through perimenopause for approximately 5-7 years prior. I am in therapy, but it does not seem to be helping. Unfortunately I cannot take any Hormone Replacement Therapy because I had one positive result for a gene that increases
I am 57 and I was considered in menopause at 52 years old, however I went through perimenopause for approximately 5-7 years prior. I am in therapy, but it does not seem to be helping. Unfortunately I cannot take any Hormone Replacement Therapy because I had one positive result for a gene that increases
Cardinals1
in
Anxiety and Depression Support
5 months ago
Progesterone post medicated FET
I'd like to ask all the ladies who conceived after a HRT/medicated FET, how much progesterone pessaries were you on? I'm on 4 x 200mg vaginal capsules so 800mg/day. Wonder if anyone is/was on a lower dosage. Just thinking about reducing to 3 x /day (600mg) having seen the patients' leaflet for Utrogestan
I'd like to ask all the ladies who conceived after a HRT/medicated FET, how much progesterone pessaries were you on? I'm on 4 x 200mg vaginal capsules so 800mg/day. Wonder if anyone is/was on a lower dosage. Just thinking about reducing to 3 x /day (600mg) having seen the patients' leaflet for Utrogestan
konyaga
in
Fertility Network UK - Pregnancy Support
5 months ago
T3 test times advice
Hi FT4: 12.22 pmol/l (Range 8 - 19.1) 38.02% FT3: 5.3 pmol/l (Range 2.4 - 6) 80.56% TSH <0.01 I take 100 t4 and 15 t3. I had the above done just before I started hrt. They are going to test again as I have felt a few of my symptoms returning. Slow bowel, sore feet etc. Nothing major but enough to
Hi FT4: 12.22 pmol/l (Range 8 - 19.1) 38.02% FT3: 5.3 pmol/l (Range 2.4 - 6) 80.56% TSH <0.01 I take 100 t4 and 15 t3. I had the above done just before I started hrt. They are going to test again as I have felt a few of my symptoms returning. Slow bowel, sore feet etc. Nothing major but enough to
BiscuitBaby
in
Thyroid UK
5 months ago
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