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starting on niraparib after frontline chemo
I’m stage 3A HGSOC and HRD+ BRCA negative and I’ve been reading quite a few posts that
Olaparib
seems to be mentioned more in connection with HRD+ so I’m just wondering if any of you lovely ladies can enlighten me further on this. Thanks x
I’m stage 3A HGSOC and HRD+ BRCA negative and I’ve been reading quite a few posts that
Olaparib
seems to be mentioned more in connection with HRD+ so I’m just wondering if any of you lovely ladies can enlighten me further on this. Thanks x
Schnauzer19
in
My Ovacome
6 months ago
slight CEA Elevation
hi everyone- my father has MBC and is currently on Lynparza /
Olaparib
to target the BRCA2 gene mutation. He has been on it for 9 months and had a scan that showed complete control over his breast cancer on May 21st (not too long ago at all).
hi everyone- my father has MBC and is currently on Lynparza /
Olaparib
to target the BRCA2 gene mutation. He has been on it for 9 months and had a scan that showed complete control over his breast cancer on May 21st (not too long ago at all).
Jenniferp2122
in
SHARE Metastatic Breast Cancer
27 days ago
Feeling like Chemo is too Hard
I was diagnosed 3B HG in August 2018, had surgery, frontline, first recurrence ( carbo and caelyx/doxil), 3 years of
Olaparib
, one year on nothing and now am having carboplatin alone for second recurrence. My oncologist said this would be relatively easy.
I was diagnosed 3B HG in August 2018, had surgery, frontline, first recurrence ( carbo and caelyx/doxil), 3 years of
Olaparib
, one year on nothing and now am having carboplatin alone for second recurrence. My oncologist said this would be relatively easy.
delia2
in
My Ovacome
4 months ago
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1 Yr on pBAT Results
Last High T cycle I started taking
Olaparib
150mg BID for just the first week of that cycle and will continue that routine for now.
Last High T cycle I started taking
Olaparib
150mg BID for just the first week of that cycle and will continue that routine for now.
KocoPr
in
Fight Prostate Cancer
1 month ago
Olaparib for Metastatic Castration-Resistant Prostate Cancer With BRCA1 and/or BRCA2 Alterations
RESULTS
Olaparib
was associated with longer rPFS (hazard ratio [HR], 0.22 [95% CI, 0.15 to 0.32]) and OS (HR, 0.63 [95% CI, 0.42 to 0.95]) than control.
RESULTS
Olaparib
was associated with longer rPFS (hazard ratio [HR], 0.22 [95% CI, 0.15 to 0.32]) and OS (HR, 0.63 [95% CI, 0.42 to 0.95]) than control.
Balsam01
in
Advanced Prostate Cancer
7 months ago
Which treatment option best for recurrent oligo?
no toxicity from the PARPi). 7
Olaparib
+ Abiraterone.
no toxicity from the PARPi). 7
Olaparib
+ Abiraterone.
Purple-Bike
in
Advanced Prostate Cancer
5 months ago
In the UK Olaparib only seems to be available for those testing positive for BRCA. Is this a cost issue that it is not widely available?
We insisted on a BRCA test which has come back negative but from what I understand
Olaparib
is only being made available to patients in the UK for those who test positive.
We insisted on a BRCA test which has come back negative but from what I understand
Olaparib
is only being made available to patients in the UK for those who test positive.
Beej59
in
Prostate Cancer Network
2 months ago
In the UK Olaparib only seems to be available for those testing positive for BRCA. Is this a cost issue that it is not widely available?
We insisted on a BRCA test which has come back negative but from what I understand
Olaparib
is only being made available to patients in the UK for those who test positive.
We insisted on a BRCA test which has come back negative but from what I understand
Olaparib
is only being made available to patients in the UK for those who test positive.
Beej59
in
Advanced Prostate Cancer
2 months ago
CA125 rising steadily
I have been receiving Avastin and
Olaparib
since April 2023 . My CA 125 was at its lowest in Sept 23 at 11 and has steadily increased since then to 43 at present .
I have been receiving Avastin and
Olaparib
since April 2023 . My CA 125 was at its lowest in Sept 23 at 11 and has steadily increased since then to 43 at present .
Norelo8
in
My Ovacome
7 days ago
Enlarged pelvic lymph node
Has anyone received surgery/radiotherapy for an enlarged pelvic lymph node and still been receiving
Olaparib
along side this? Sending best wishes Lisa
Has anyone received surgery/radiotherapy for an enlarged pelvic lymph node and still been receiving
Olaparib
along side this? Sending best wishes Lisa
Alfiepop
in
My Ovacome
8 months ago
Leo 2327
Hi to all the ladies on this journey I am 3c ovarian cancer since May 2022 had 8 lots of chemo and debulking surgery and stoma then been on avastin for over a year last one next Friday and also take
olaparib
I am NED at the moment but I am suffering realy bad with hot sweats and tiredness is anyone else
Hi to all the ladies on this journey I am 3c ovarian cancer since May 2022 had 8 lots of chemo and debulking surgery and stoma then been on avastin for over a year last one next Friday and also take
olaparib
I am NED at the moment but I am suffering realy bad with hot sweats and tiredness is anyone else
Leo2327
in
My Ovacome
6 months ago
Olaparib hasn’t worked for me . Anyone had this happen and had success with another PARP?
This is just a year after 1st recurrence, Chemo reduced cancer to nearly NED, 7 months of
Olaparib
and then CT scan showed new tumour on spleen. CA125 36. Oncologist mentioned later trying another PARP possibly Rucaparib. Anyone had success when one didn’t work ?
This is just a year after 1st recurrence, Chemo reduced cancer to nearly NED, 7 months of
Olaparib
and then CT scan showed new tumour on spleen. CA125 36. Oncologist mentioned later trying another PARP possibly Rucaparib. Anyone had success when one didn’t work ?
Towergirl
in
My Ovacome
6 months ago
Had enough
My battle has been mental , compared with lots of you ive had far less treatment .. major debulking with splenectomy , Avastin and now
olaparib
and my ca125 and Ct ‘s have been fine ….
My battle has been mental , compared with lots of you ive had far less treatment .. major debulking with splenectomy , Avastin and now
olaparib
and my ca125 and Ct ‘s have been fine ….
PWT1
in
My Ovacome
3 months ago
can pleural effusion alone come back?
Have been NED since first line ended in June 22, and been on
olaparib
since. Day before, did a chest X-ray as part of my master checkup and it shows a slight blunt in the right lung (costoprenic angle), seems similar to the first time.
Have been NED since first line ended in June 22, and been on
olaparib
since. Day before, did a chest X-ray as part of my master checkup and it shows a slight blunt in the right lung (costoprenic angle), seems similar to the first time.
Goodgirl98
in
My Ovacome
3 months ago
Neuropathy worse after covid jab, anyone?
I am 3 years since diagnosis 4b, carbo taxol, debulking, and now 4 months finished with a 2 year
Olaparib
course.
I am 3 years since diagnosis 4b, carbo taxol, debulking, and now 4 months finished with a 2 year
Olaparib
course.
Trickysite
in
My Ovacome
2 months ago
Olaparib side effects
Just looking to hear from anyone who might be having side effects with
Olaparib
I have been taking 300mg a day for almost 18 months. It’s been very tolerable until a few weeks ago. Started with shoulder pain but now every joint and muscle hurts ( especially first thing in the morning).
Just looking to hear from anyone who might be having side effects with
Olaparib
I have been taking 300mg a day for almost 18 months. It’s been very tolerable until a few weeks ago. Started with shoulder pain but now every joint and muscle hurts ( especially first thing in the morning).
Mysticmeg123
in
My Ovacome
8 months ago
Clinical Trial PT 112 ?
BRCR 1 gene mutation so with Zytiga tried Niraparib in clinical trial but was in fact placebo so when PSA started climbing began
Olaparib
(Lynparza) - not effective so in November ‘23 began chemo Docetaxel ( PSA up to 500 ) with additional drug : Capivasertib (in Capitello trial) After 4 rounds slight
BRCR 1 gene mutation so with Zytiga tried Niraparib in clinical trial but was in fact placebo so when PSA started climbing began
Olaparib
(Lynparza) - not effective so in November ‘23 began chemo Docetaxel ( PSA up to 500 ) with additional drug : Capivasertib (in Capitello trial) After 4 rounds slight
Enilorac63
in
Advanced Prostate Cancer
5 months ago
Olaparib and Radium 223 synergy ?
I seem to recall seeing that there was a trial on seeing if there was synergy to taking
Olaparib
and Radium 223. But can not find it. Anyone have any knowledge of this? I'm BRCA2 mutated and currently taking
Olaparib
, and considering Radium 223. Thanks.
I seem to recall seeing that there was a trial on seeing if there was synergy to taking
Olaparib
and Radium 223. But can not find it. Anyone have any knowledge of this? I'm BRCA2 mutated and currently taking
Olaparib
, and considering Radium 223. Thanks.
davebliz
in
Advanced Prostate Cancer
9 months ago
Feeling fed up
Had chemo / radical op/ chemo/
olaparib
/ more chemo now starting again with diff chemo. Last time and this due to lymph nodes misbehaving . I don't even feel Ill! Got few niggley aches. I feel strong to do this but I've got all the T shirts and just want a break.
Had chemo / radical op/ chemo/
olaparib
/ more chemo now starting again with diff chemo. Last time and this due to lymph nodes misbehaving . I don't even feel Ill! Got few niggley aches. I feel strong to do this but I've got all the T shirts and just want a break.
Casamimosa
in
My Ovacome
5 months ago
Rising CA125- confused !!
Great results after chemo, debulking op and 2 years on
Olaparib
. The last 5 months my CA125 has been rising the most recent being 742 . I've had 2 scans and no sign of cancer but I do have hernia and gall stones in my bile ducts.
Great results after chemo, debulking op and 2 years on
Olaparib
. The last 5 months my CA125 has been rising the most recent being 742 . I've had 2 scans and no sign of cancer but I do have hernia and gall stones in my bile ducts.
Rhonddalady
in
My Ovacome
7 months ago
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