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Lutetium at earlier stage, clinical trial is enrolling
The second trial provides men with metastatic prostate cancer access to prostate-specific membrane antigen (PSMA)-targeted therapy prior to chemotherapy. Currently, PSMA-targeted therapy is only available after chemotherapy. However, phase III clinical trials have shown that PSMA-targeted therapies are
The second trial provides men with metastatic prostate cancer access to prostate-specific membrane antigen (PSMA)-targeted therapy prior to chemotherapy. Currently, PSMA-targeted therapy is only available after chemotherapy. However, phase III clinical trials have shown that PSMA-targeted therapies are
Maxone73
in
Advanced Prostate Cancer
4 months ago
Starting clinical trial of AVR-766
Today I start a clinical trial for ARV-766, an AR degrader. I'm coming in at phase 2, and they are only accepting men who have one of 4 point mutations in the AR - I have two. I've been randomized to 300 mg pill, once a day. The other dose is 100mg. I've failed ADT, chemo. Keytruda & Pluvicto. Hoping
Today I start a clinical trial for ARV-766, an AR degrader. I'm coming in at phase 2, and they are only accepting men who have one of 4 point mutations in the AR - I have two. I've been randomized to 300 mg pill, once a day. The other dose is 100mg. I've failed ADT, chemo. Keytruda & Pluvicto. Hoping
rsgdmd
in
Advanced Prostate Cancer
4 months ago
After Zytiga-Xtandi Fail!
Following up on a post by "Chris52981", after Zytiga and Xtandi fail, if chemo is the next treatment, how much time do we really buy? Is it Month's? Weeks? or Years?
Following up on a post by "Chris52981", after Zytiga and Xtandi fail, if chemo is the next treatment, how much time do we really buy? Is it Month's? Weeks? or Years?
TommyCarz2
in
Advanced Prostate Cancer
4 months ago
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Recent HF diagnosis
Hi, I was diagnosed with heart failure a couple of months ago when I woke up one morning struggling for breath with fluid in my lungs, having had virtually no previous symptoms. Looking back, maybe I was a bit short of breath over the last few months but did a sprint-distance triathlon 6 months ago so
Hi, I was diagnosed with heart failure a couple of months ago when I woke up one morning struggling for breath with fluid in my lungs, having had virtually no previous symptoms. Looking back, maybe I was a bit short of breath over the last few months but did a sprint-distance triathlon 6 months ago so
izzibear
in
British Heart Foundation
4 months ago
PSA after chemo # 4
Hi My husbands last chemo was # 3 and PSA was 0.14, he just got the results from Chemo # 4 and it was at 0.12. This is the slowest decline if you look in the profile Iisted all his PSA results. Should we be worried that this last one barely moved ? Or is this slower decline good news? Thanks for any
Hi My husbands last chemo was # 3 and PSA was 0.14, he just got the results from Chemo # 4 and it was at 0.12. This is the slowest decline if you look in the profile Iisted all his PSA results. Should we be worried that this last one barely moved ? Or is this slower decline good news? Thanks for any
positive-thinking
in
Advanced Prostate Cancer
4 months ago
I need urgent help for my uncle.
My uncle who resides in France and is a holder of a French citizenship, has been diagnosed with terminal prostatic cancer. He had treated this condition in the past but it ultimately came back, but this time around doctors (including a specialist in Marseille) made him know that his condition was incurable
My uncle who resides in France and is a holder of a French citizenship, has been diagnosed with terminal prostatic cancer. He had treated this condition in the past but it ultimately came back, but this time around doctors (including a specialist in Marseille) made him know that his condition was incurable
Admhdu
in
Advanced Prostate Cancer
4 months ago
I need urgent help for my uncle
My uncle who resides in France and is a holder of a French citizenship, has been diagnosed with terminal prostatic cancer. He had treated this condition in the past but it ultimately came back, but this time around doctors (including a specialist in Marseille) made him know that his condition was incurable
My uncle who resides in France and is a holder of a French citizenship, has been diagnosed with terminal prostatic cancer. He had treated this condition in the past but it ultimately came back, but this time around doctors (including a specialist in Marseille) made him know that his condition was incurable
Admhdu
in
Advanced Prostate Cancer
4 months ago
chemo
has anyone who failed xtandi and zytiga have good outcome with chemo- does it completely eliminate the cancer or do you still have to take things after - how does it work when it stops - also can you take it in smaller doses?
has anyone who failed xtandi and zytiga have good outcome with chemo- does it completely eliminate the cancer or do you still have to take things after - how does it work when it stops - also can you take it in smaller doses?
Chris52981
in
Advanced Prostate Cancer
4 months ago
Treatment plan / second opinions
hi everyone! first time poster - probably won’t be my last !! Just at the start of this journey, mums getting her Treatment Plan for first line treatment on Friday and I’d love any thoughts on what questions we should be asking? And would this be the stage for getting a second opinion (and is it
hi everyone! first time poster - probably won’t be my last !! Just at the start of this journey, mums getting her Treatment Plan for first line treatment on Friday and I’d love any thoughts on what questions we should be asking? And would this be the stage for getting a second opinion (and is it
georgiageorgia182
in
My Ovacome
4 months ago
what have I joined?
I have a Brian tumour had the surgery now going to treatment radio chemo etc… Been told exercise is good Any advice on how much? Or little? any tips on best diets
I have a Brian tumour had the surgery now going to treatment radio chemo etc… Been told exercise is good Any advice on how much? Or little? any tips on best diets
Ppmoorman65
in
Glioblastoma Support
4 months ago
Rechallenge Docetaxel - more than 6?
My husband has just finished his rechallenge of Docetaxel on 2/29x He did 6 rounds and while things are shrinking it didn’t have the significant change I think they wanted. So his MO at Mayo now wants him to do more chemo until he can no longer tolerate. It’s the standard 75g and my wrestle is why
My husband has just finished his rechallenge of Docetaxel on 2/29x He did 6 rounds and while things are shrinking it didn’t have the significant change I think they wanted. So his MO at Mayo now wants him to do more chemo until he can no longer tolerate. It’s the standard 75g and my wrestle is why
mdiaz76
in
Advanced Prostate Cancer
4 months ago
Discoloured teeth
Has anyone had trouble with discolouration of their teeth? I have been cleaning regularly but was told to rinse with corsodyl which I think is the cause of the problem. Of course, I haven't been to a hygienist in ages as still having chemotherapy. I know this is a cosmetic thing but it is really getting
Has anyone had trouble with discolouration of their teeth? I have been cleaning regularly but was told to rinse with corsodyl which I think is the cause of the problem. Of course, I haven't been to a hygienist in ages as still having chemotherapy. I know this is a cosmetic thing but it is really getting
Swimbuddy
in
My Ovacome
4 months ago
Confused
UPDATE: April 5, 2024 Yesterday was very disappointing as my husbands PSA increased again by 183 points, last month his PSA was 1546 and now it is 1730. All his other CBC results were good. His Alkaline Phosphatase increased 6 points, last month 127 and now 133 but still in range of 40-150. Questioned
UPDATE: April 5, 2024 Yesterday was very disappointing as my husbands PSA increased again by 183 points, last month his PSA was 1546 and now it is 1730. All his other CBC results were good. His Alkaline Phosphatase increased 6 points, last month 127 and now 133 but still in range of 40-150. Questioned
MsHope
in
Advanced Prostate Cancer
4 months ago
CLL survival times ARE improving, thanks to BTK and BCL-2 inhibitors
Many of us were shocked after our CLL/SLL diagnosis when we googled for survival times. [u]Hopefully[/u] we subsequently read that search engine information from Google, Bing, etc., is way out of date, due to the fact that with CLL being a chronic disease, the relatively long survival times with this
Many of us were shocked after our CLL/SLL diagnosis when we googled for survival times. [u]Hopefully[/u] we subsequently read that search engine information from Google, Bing, etc., is way out of date, due to the fact that with CLL being a chronic disease, the relatively long survival times with this
AussieNeil
Partner
in
CLL Support
4 months ago
Living day by day
I have small Cell lung cancer received chemo and radiation ended treatment March 2023 all clear, restaged cat scan in Sept of 2023 and it was back started immunotherapy opdiva starting end of Sept 2023 the tumor didn't leave but wasn't spreading. In jan was diagnosed with a numerological issue and can't
I have small Cell lung cancer received chemo and radiation ended treatment March 2023 all clear, restaged cat scan in Sept of 2023 and it was back started immunotherapy opdiva starting end of Sept 2023 the tumor didn't leave but wasn't spreading. In jan was diagnosed with a numerological issue and can't
Watermelon67
in
The Roy Castle Lung Cancer Foundation
4 months ago
Bone pain, what next?
For over 2 years my scans show no radiographic progression despite a rising PSA, now at 43. However I am now experiencing periodic bone pain in the left hip area, mainly when I climb stairs. Tolerable but a worrying development. Even with lack of visible progression I think we need to change something
For over 2 years my scans show no radiographic progression despite a rising PSA, now at 43. However I am now experiencing periodic bone pain in the left hip area, mainly when I climb stairs. Tolerable but a worrying development. Even with lack of visible progression I think we need to change something
Ian99
in
Advanced Prostate Cancer
4 months ago
Second Line Hormonal
I am still only receiving Zoladex injections every three months. I did try Abiraterone 2022/2023 and it failed after a few months. I have been trying to get my Oncologist to prescribe Enzalutamide. I have been treated with docetaxel again and thought it might re-sensitize me for another hormonal drug
I am still only receiving Zoladex injections every three months. I did try Abiraterone 2022/2023 and it failed after a few months. I have been trying to get my Oncologist to prescribe Enzalutamide. I have been treated with docetaxel again and thought it might re-sensitize me for another hormonal drug
Islandboy2021
in
Advanced Prostate Cancer
4 months ago
Spot Radiation before Pluvicto?
Haven’t posted for a while about Mr. Spouse21 until I had some data as his PSA began to tick up a few months ago. Last week a PET FDG confirmed recent bone and CT scans. Summary of main results:
Multiple tracer avid osseous metastases. Most prominent involving right margin of T12.
Mr.Spouse was
Haven’t posted for a while about Mr. Spouse21 until I had some data as his PSA began to tick up a few months ago. Last week a PET FDG confirmed recent bone and CT scans. Summary of main results:
Multiple tracer avid osseous metastases. Most prominent involving right margin of T12.
Mr.Spouse was
spouse21
in
Advanced Prostate Cancer
4 months ago
Feeling like Chemo is too Hard
Hi. I was diagnosed 3B HG in August 2018, had surgery, frontline, first recurrence ( carbo and caelyx/doxil), 3 years of Olaparib, one year on nothing and now am having carboplatin alone for second recurrence. My oncologist said this would be relatively easy. Also I haven’t had some of the worst complications
Hi. I was diagnosed 3B HG in August 2018, had surgery, frontline, first recurrence ( carbo and caelyx/doxil), 3 years of Olaparib, one year on nothing and now am having carboplatin alone for second recurrence. My oncologist said this would be relatively easy. Also I haven’t had some of the worst complications
delia2
in
My Ovacome
4 months ago
Is it needed and safe for my mom to supplement with folate or B12?
Hi all! I haven't posted before but I've been reading for a few months and find everything really helpful. My mom has had both chemotherapy and radiation this last year, and now has many overlapping symptoms with b12 and folate deficiencies (fatigue, mild neuropathy for years, mild memory loss/confusion
Hi all! I haven't posted before but I've been reading for a few months and find everything really helpful. My mom has had both chemotherapy and radiation this last year, and now has many overlapping symptoms with b12 and folate deficiencies (fatigue, mild neuropathy for years, mild memory loss/confusion
Jr499
in
Pernicious Anaemia Society
4 months ago
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