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Levodopa
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Sonic hedgehog can suppress L-dopa induced dyskinesia
https://parkinsonsnewstoday.com/2021/09/28/imbalances-brain-dopamine-sonic-hedgehog-lid-l-dopa-induced-dyskinesia-parkinsons/
https://parkinsonsnewstoday.com/2021/09/28/imbalances-brain-dopamine-sonic-hedgehog-lid-l-dopa-induced-dyskinesia-parkinsons/
Hidden
in
Cure Parkinson's
3 years ago
Mucuna dosage help please
Can any of you bright folk help me out with the dosage here please. I take this mucuna powder 99.6% l-dopa. I find it really helpful. (See photo) Am I right in assuming that 1/8 tsp is 500mg which is equivalent to 5 senimet tabs of 25/100? Surely that can’t be right! What am I missing here??? (And
Can any of you bright folk help me out with the dosage here please. I take this mucuna powder 99.6% l-dopa. I find it really helpful. (See photo) Am I right in assuming that 1/8 tsp is 500mg which is equivalent to 5 senimet tabs of 25/100? Surely that can’t be right! What am I missing here??? (And
saraoutwest
in
Cure Parkinson's
3 years ago
A Curmudgeonly Approach to Supplements and Research "Progress." 😊
They always circled back to that dreaded carbidopa
levodopa
stuff even though it had horrible side effects and they weren't particularly encouraging or enlightening.
They always circled back to that dreaded carbidopa
levodopa
stuff even though it had horrible side effects and they weren't particularly encouraging or enlightening.
jimcaster
in
Cure Parkinson's
3 years ago
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Parkinson's could be otherwise.
The patient had been diagnosed as usual, responded well to Sinemet (
levodopa
/carbidopa) and a SPECT DaT test confirmed the diagnosis. Neuroscientist Karishma Smart and colleagues published in 2016.
The patient had been diagnosed as usual, responded well to Sinemet (
levodopa
/carbidopa) and a SPECT DaT test confirmed the diagnosis. Neuroscientist Karishma Smart and colleagues published in 2016.
parkinsonshereandnow
in
Cure Parkinson's
3 years ago
Where to from here?
Prescribed
levodopa
with no effect on any symptoms, 3 months later diagnosis changed to possibly PSP. This confirmed 2 mths later by neurologist. Who basically said 'no treatment, no cure, no point in coming to see me again and if you fall it could be the end for you'. OUCH!
Prescribed
levodopa
with no effect on any symptoms, 3 months later diagnosis changed to possibly PSP. This confirmed 2 mths later by neurologist. Who basically said 'no treatment, no cure, no point in coming to see me again and if you fall it could be the end for you'. OUCH!
BlairWit
in
PSP Association
3 years ago
B6 recommended with carbidopa levodopa.
I am 2.5 years dx with Pd and just started carbidopa
levodopa
. It helped quite a bit and took b6 (for depression) this morning and was amazed at how good I felt. Like I was 100 percent normal. I took too much as I have read.
I am 2.5 years dx with Pd and just started carbidopa
levodopa
. It helped quite a bit and took b6 (for depression) this morning and was amazed at how good I felt. Like I was 100 percent normal. I took too much as I have read.
38yroldmale
in
Cure Parkinson's
3 years ago
Vinpocetine regulates levels of circulating TLRs in Parkinson's disease patients 2019
Furthermore, vinpocetine produced a robust increase in the Mini Mental State Examination score, compared to that achieved by using
levodopa
therapy. Conclusion: Vinpocetine treatment may exhibit anti-inflammatory activity and alleviate cognitive impairment.
Furthermore, vinpocetine produced a robust increase in the Mini Mental State Examination score, compared to that achieved by using
levodopa
therapy. Conclusion: Vinpocetine treatment may exhibit anti-inflammatory activity and alleviate cognitive impairment.
Bolt_Upright
in
Cure Parkinson's
3 years ago
DO YOU USE MUCUNA P FOR PD?
If you answer YES to all the above questions ,kindly let me know your brand of Mucuna, the % concentration of
Levodopa
and where to purchase it. Thanks for your reply.
If you answer YES to all the above questions ,kindly let me know your brand of Mucuna, the % concentration of
Levodopa
and where to purchase it. Thanks for your reply.
OREOLU
in
Cure Parkinson's
3 years ago
Associations between osteoporosis and drug exposure: a post-marketing study of the World Health Organization pharmacovigilance database
New disproportionality signals with a pharmacologically plausible mechanism were found for drugs used in neurology (
levodopa
(ROR [95%CI]: 10.18 [4.33-25.10]), selective serotonin agonists (4.22 [2.34-7.00]) and memantine (4.10 [1.56-8.93])), hematology (romiplostim (4.93 [1.15-21.10])), pulmonology
New disproportionality signals with a pharmacologically plausible mechanism were found for drugs used in neurology (
levodopa
(ROR [95%CI]: 10.18 [4.33-25.10]), selective serotonin agonists (4.22 [2.34-7.00]) and memantine (4.10 [1.56-8.93])), hematology (romiplostim (4.93 [1.15-21.10])), pulmonology
helvella
Thyroid UK
in
Thyroid UK
3 years ago
Typical med progression?
My friend started taking l-dopa within the past year. She works fulltime and her workplace isn't aware of her diagnosis. Currently she's taking 8 Sinemet 100mg daily, plus 3 or 4 Rytary 145mg. She also takes sleeping medication, and botox for curled toes. She's reading articles on DBS. Any advice
My friend started taking l-dopa within the past year. She works fulltime and her workplace isn't aware of her diagnosis. Currently she's taking 8 Sinemet 100mg daily, plus 3 or 4 Rytary 145mg. She also takes sleeping medication, and botox for curled toes. She's reading articles on DBS. Any advice
genesurf
in
Cure Parkinson's
3 years ago
Hands up all those who have heard of belly dancer's dyskinesia (BDD)
Levodopa
-induced belly dancer's dyskinesia: Case report https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8298813/
Levodopa
-induced belly dancer's dyskinesia: Case report https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8298813/
jeffreyn
in
Cure Parkinson's
3 years ago
Can anyone tell me why sometimes 100mg/10 mg levodopa/carbidopa is used instead of standard 100/25 version
Sinemet 100/10
Sinemet 100/10
Connie18
in
Cure Parkinson's
3 years ago
ARE YOU A NON TREMOR DOMINANT PD PATIENT WITH DYSKINESIA? IF SO, PLEASE HELP.
My MDS thinks it is motor fluctuations, caused by uneven plasma level of
Levodopa
. He suggested that I should add two more pills, as a last dose, with adjustment of schedule i.e(8am,12noon,3pm,7pm and 11pm), since I am experiencing more of a wearing off dyskinesia.
My MDS thinks it is motor fluctuations, caused by uneven plasma level of
Levodopa
. He suggested that I should add two more pills, as a last dose, with adjustment of schedule i.e(8am,12noon,3pm,7pm and 11pm), since I am experiencing more of a wearing off dyskinesia.
OREOLU
in
Cure Parkinson's
3 years ago
PART 2 : Reversing Memory Deficits And Senior Moments In A 78 Year Old
significant fanfare whatsoever. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8349115/ >>>>>>> A warning regarding Citicoline in PwP <<<<<<< Although this new study above suggests that Citicoline is likely useful in terms of memory improvement, Citicoline is also suggested to be useful in promotion of
levodopa
significant fanfare whatsoever. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8349115/ >>>>>>> A warning regarding Citicoline in PwP <<<<<<< Although this new study above suggests that Citicoline is likely useful in terms of memory improvement, Citicoline is also suggested to be useful in promotion of
levodopa
chartist
in
Cure Parkinson's
3 years ago
Dopamine agonists or levodopa?
I am 53 and was diagnosed PD 8 years . I am currently on 1/2 spoon of Zandopa and 1/4 Sinemet, 4 times a day. The medication only lasts for about 2 hours, so each day has been a hell for me. I am currently deciding on whether I should go with dopamine agonists first, or I should add more zandopa/ Macuna
I am 53 and was diagnosed PD 8 years . I am currently on 1/2 spoon of Zandopa and 1/4 Sinemet, 4 times a day. The medication only lasts for about 2 hours, so each day has been a hell for me. I am currently deciding on whether I should go with dopamine agonists first, or I should add more zandopa/ Macuna
LauraYu
in
Cure Parkinson's
3 years ago
Dose Adjustment
My Dose Carbidopa
levodopa
IR 25/100 (2) Thiamine hcl 4 grams daily. Tentatively Carbidopa
levodopa
IR 25/100 (1) Thiamine hcl 6 grams daily.
My Dose Carbidopa
levodopa
IR 25/100 (2) Thiamine hcl 4 grams daily. Tentatively Carbidopa
levodopa
IR 25/100 (1) Thiamine hcl 6 grams daily.
Hidden
in
Cure Parkinson's
3 years ago
Plantago ovata husk (psyllium) administration caused a smoothing and homogenization of levodopa absorption
Plantago ovata husk (psyllium) administration caused a smoothing and homogenization of
levodopa
absorption, providing more stable concentrations and final higher levels, resulting in a great benefit for patients. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4139609/
Plantago ovata husk (psyllium) administration caused a smoothing and homogenization of
levodopa
absorption, providing more stable concentrations and final higher levels, resulting in a great benefit for patients. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4139609/
Thal
in
Cure Parkinson's
3 years ago
Gene Therapy Success With Ties to Parkinson’s Disease
Both conditions are associated with deficiencies of AADC, which converts
levodopa
into dopamine, a neurotransmitter involved in movement, mood, learning and concentration." https://www.ucsf.edu/news/2021/07/420986/gene-therapy-offers-long-awaited-hope-children-rare-incurable-disorder
Both conditions are associated with deficiencies of AADC, which converts
levodopa
into dopamine, a neurotransmitter involved in movement, mood, learning and concentration." https://www.ucsf.edu/news/2021/07/420986/gene-therapy-offers-long-awaited-hope-children-rare-incurable-disorder
jimcaster
in
Cure Parkinson's
3 years ago
Sinemet v carbo levodopa g
Sinemet is the Origina make/brand for
levodopa
and I have always had this made by Merrick Sharp Dohme Recently in found to my cost that it longer under special licence and it can be made by anyone now, but I was unaware that they would have such a different effect on me.
Sinemet is the Origina make/brand for
levodopa
and I have always had this made by Merrick Sharp Dohme Recently in found to my cost that it longer under special licence and it can be made by anyone now, but I was unaware that they would have such a different effect on me.
Connie18
in
Cure Parkinson's
3 years ago
Would Adding 10,000 IU a day of D3 would be a good thing to complement my Niacin 250 mg a day? Maybe NOT
Sometimes I'm Stupid. This is a re-write of my post extolling the virtues of vitamin D3 based on misreading a study and thinking down was up and left was right. I would just delete it but some people have seen it and I want the correction to be here. This is the trial from 2016 that had me excited:
Sometimes I'm Stupid. This is a re-write of my post extolling the virtues of vitamin D3 based on misreading a study and thinking down was up and left was right. I would just delete it but some people have seen it and I want the correction to be here. This is the trial from 2016 that had me excited:
Bolt_Upright
in
Cure Parkinson's
3 years ago
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