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Time for a sea change?
Besides, selegiline was more tolerable than bromocriptine (OR = 0.62, CI: 0.39 to 0.98) and pramipexole had a higher withdraw rate than
levodopa
.” I think Prami and Requip should be banned and everyone switched over to Neupro until they can be comfortably withdrawn from even that.
Besides, selegiline was more tolerable than bromocriptine (OR = 0.62, CI: 0.39 to 0.98) and pramipexole had a higher withdraw rate than
levodopa
.” I think Prami and Requip should be banned and everyone switched over to Neupro until they can be comfortably withdrawn from even that.
Hidden
in
Restless Legs Syndrome
3 years ago
TEN (10) years and what have you learned?
What have you learned in respect to carbidopa
levodopa
?
What have you learned in respect to carbidopa
levodopa
?
Hidden
in
Cure Parkinson's
3 years ago
Parkinson's Disease - Hydrogen & Dopamine discussion with Dr. Joerg Birkmeyer and Mark Kent 11/26/2021
Parkinson's Disease - Hydrogen & Dopamine discussion with Dr. Joerg Birkmeyer and Mark Kent 11/26/2021 - https://youtu.be/py20sLqHeFs We discuss the relationship between hydrogen gas, L-Dopa, Dopamine and and how hydrogen producing bacteria can be the root cause of Parkinson's Disease and potential new
Parkinson's Disease - Hydrogen & Dopamine discussion with Dr. Joerg Birkmeyer and Mark Kent 11/26/2021 - https://youtu.be/py20sLqHeFs We discuss the relationship between hydrogen gas, L-Dopa, Dopamine and and how hydrogen producing bacteria can be the root cause of Parkinson's Disease and potential new
Bolt_Upright
in
Cure Parkinson's
3 years ago
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RLS and Parkinson's
Hi everyone, I'm new here but have been reading a lot of posts and find it very helpful. Great to find this community that support each other. I wanted to tell about my mother’s condition to see if anyone has any helpful tips or insights. My mum has been diagnosed with Parkinson recently and has started
Hi everyone, I'm new here but have been reading a lot of posts and find it very helpful. Great to find this community that support each other. I wanted to tell about my mother’s condition to see if anyone has any helpful tips or insights. My mum has been diagnosed with Parkinson recently and has started
Fernando80
in
Restless Legs Syndrome
3 years ago
Mucuna puriens 1000mg
I also take Asian herbs prescribed by my acupuncturist which contains some
levodopa
three times a day. I took one 1000 MP capsule and my blood pressure and pulse shot up and I became very shaky.
I also take Asian herbs prescribed by my acupuncturist which contains some
levodopa
three times a day. I took one 1000 MP capsule and my blood pressure and pulse shot up and I became very shaky.
Lin1950
in
Cure Parkinson's
3 years ago
Equivalence between C/L meds and Mucuna Pruriens.
Might a standard 100/25 C/L tablet be as powerful as 500mg of
levodopa
from mucuna? And are there deleterious effects from the extra
levodopa
in the non-brain blood system when taking higher amounts of mucuna-sourced
levodopa
?
Might a standard 100/25 C/L tablet be as powerful as 500mg of
levodopa
from mucuna? And are there deleterious effects from the extra
levodopa
in the non-brain blood system when taking higher amounts of mucuna-sourced
levodopa
?
puretone
in
Cure Parkinson's
3 years ago
what improvements
Currently **No
Levodopa
** and my gauge is how often *does my right hand shake* (pretty much only when I am trying to have a bowel movement)… I believe the BCM-95 has helped noticeably with my neck pain and KSM-66 has helped with clarity of my mind… I have high hopes that BCM-95 will be a maintenance
Currently **No
Levodopa
** and my gauge is how often *does my right hand shake* (pretty much only when I am trying to have a bowel movement)… I believe the BCM-95 has helped noticeably with my neck pain and KSM-66 has helped with clarity of my mind… I have high hopes that BCM-95 will be a maintenance
Gcf51
in
Cure Parkinson's
3 years ago
gut problems and medication effectiveness
hi all http://www.sci-news.com/medicine/gut-bacteria-
levodopa
-07328.html just read this and found it interesting, I definitely have major problems with medication effectiveness and digestive issues.
hi all http://www.sci-news.com/medicine/gut-bacteria-
levodopa
-07328.html just read this and found it interesting, I definitely have major problems with medication effectiveness and digestive issues.
Todd-pw
in
Cure Parkinson's
3 years ago
Underprescribing Sinemet for PD?
In 'The New PD Treatment Book' (2015) by Eric Ahlskog he says on page 164, start with one carbidopa/
levodopa
25/100 3x daily, week 2 up the dose to 1.5 tablets 3x daily, week 3 increase to 2 tablets 3x daily, week 4 increase to 2.5; week 5 try 3 tablets 3x daily.
In 'The New PD Treatment Book' (2015) by Eric Ahlskog he says on page 164, start with one carbidopa/
levodopa
25/100 3x daily, week 2 up the dose to 1.5 tablets 3x daily, week 3 increase to 2 tablets 3x daily, week 4 increase to 2.5; week 5 try 3 tablets 3x daily.
ramotswe
in
Cure Parkinson's
3 years ago
How long before levodopa stops working in Parkinson’s disease?
After taking
levodopa
for some time, typically a few years, patients may begin to experience a wearing off period, when symptoms return before it's time for their next dose of
levodopa
. This is also referred to as "off time.”
After taking
levodopa
for some time, typically a few years, patients may begin to experience a wearing off period, when symptoms return before it's time for their next dose of
levodopa
. This is also referred to as "off time.”
Farooqji
in
Cure Parkinson's
3 years ago
It is settled then. Everyone is supportive of bringing focus to our Zoom meetings. Meeting will be formatted & shortened to 1 hour.
Greetings Zoomers, Discussion items for our next meeting: 1) All things
Levodopa
: When were you diagnosed, when did you start C/L, how much C/L do you take now, for which symptoms, how did you titrate up, do you have side effects, and have you ever reduced your dose?
Greetings Zoomers, Discussion items for our next meeting: 1) All things
Levodopa
: When were you diagnosed, when did you start C/L, how much C/L do you take now, for which symptoms, how did you titrate up, do you have side effects, and have you ever reduced your dose?
MBAnderson
in
Cure Parkinson's
3 years ago
Statin use may have a detrimental effect (faster increase in levodopa & dementia conversion )
"This study suggests that statin use may have a detrimental effect on baseline nigrostriatal dopamine degeneration and long-term outcomes in patients with Parkinson’s disease." https://academic.oup.com/brain/advance-article-abstract/doi/10.1093/brain/awab292/6339771
"This study suggests that statin use may have a detrimental effect on baseline nigrostriatal dopamine degeneration and long-term outcomes in patients with Parkinson’s disease." https://academic.oup.com/brain/advance-article-abstract/doi/10.1093/brain/awab292/6339771
Hidden
in
Cure Parkinson's
3 years ago
More Bee Stuff: Synergistic action of propolis with levodopa in the management of Parkinsonism in Drosophila melanogaster - 2020
Since
levodopa
metabolism has been associated with reactive oxygen species [15, 16], findings in the study offer a novel option for use in integrative medicine i. e. use of
levodopa
and propolis to minimize on the side effects of
levodopa
therapy.
Since
levodopa
metabolism has been associated with reactive oxygen species [15, 16], findings in the study offer a novel option for use in integrative medicine i. e. use of
levodopa
and propolis to minimize on the side effects of
levodopa
therapy.
Bolt_Upright
in
Cure Parkinson's
3 years ago
New extended release Levodopa formulation
Amneal Announces Positive Topline Results from Pivotal Phase 3 RISE-PD Clinical Trial of IPX-203 in Patients with Parkinson’s Disease Who Experience Motor Fluctuations. IPX-203 (CD/LD extended-release capsules) In individuals who experience motor fluctuations; have 0.53 more hours of “Good On” time.
Amneal Announces Positive Topline Results from Pivotal Phase 3 RISE-PD Clinical Trial of IPX-203 in Patients with Parkinson’s Disease Who Experience Motor Fluctuations. IPX-203 (CD/LD extended-release capsules) In individuals who experience motor fluctuations; have 0.53 more hours of “Good On” time.
Buckholt
in
Cure Parkinson's
3 years ago
Citicoline as Adjuvant Therapy in Parkinson's Disease: A Systematic Review 2017
Citicoline allowed effective reduction of
levodopa
by up to 50%. Significant improvement in cognitive status evaluation was also noted with citicoline adjunctive therapy.
Citicoline allowed effective reduction of
levodopa
by up to 50%. Significant improvement in cognitive status evaluation was also noted with citicoline adjunctive therapy.
Bolt_Upright
in
Cure Parkinson's
3 years ago
Side effects of levodopa. And you thought that your imagination was running wild.
https://www.drugs.com/sfx/sinemet-side-effects.html I recognize many of them as questions to healthunlocked. I have been dealing with some of them myself. Mary
https://www.drugs.com/sfx/sinemet-side-effects.html I recognize many of them as questions to healthunlocked. I have been dealing with some of them myself. Mary
parkie13
in
Cure Parkinson's
3 years ago
Supplementary management with Pycnogenol® in Parkinson's disease to prevent cognitive impairment 2020
The management for these patients was a monotherapy using carbidopa/
levodopa
(standard management; SM). Supplementary Pycnogenol® was used at 150 mg/day for 4 weeks. The neurological management was not affected.
The management for these patients was a monotherapy using carbidopa/
levodopa
(standard management; SM). Supplementary Pycnogenol® was used at 150 mg/day for 4 weeks. The neurological management was not affected.
Bolt_Upright
in
Cure Parkinson's
3 years ago
Advise on drug s
Which drug would compliment carbidopa-
levodopa
to make it last long with the least side effects
Which drug would compliment carbidopa-
levodopa
to make it last long with the least side effects
akgirlsrock
in
Cure Parkinson's
3 years ago
Carbidopa/Levodopa Success Stories
Perhaps you saw Jim's recent excellent post "The Value Of Carbidopa
Levodopa
Demonstrated in Two Signatures" at https://healthunlocked.com/cure-parkinsons/posts/146518581/the-value-of-carbidopa-
levodopa
-demonstrated-in-two-signatures How has carbidopa/
levodopa
helped you?
Perhaps you saw Jim's recent excellent post "The Value Of Carbidopa
Levodopa
Demonstrated in Two Signatures" at https://healthunlocked.com/cure-parkinsons/posts/146518581/the-value-of-carbidopa-
levodopa
-demonstrated-in-two-signatures How has carbidopa/
levodopa
helped you?
Hidden
in
Cure Parkinson's
3 years ago
Clinical Trial Highlights – an update on previously reviewed trials (Phase 3 in focus)
Intec Pharma’s gastric retentive Accordion Pill™ Carbidopa/
Levodopa
(AP-CD/LD) was being evaluated in a phase 3 study for its safety and efficacy in advanced PD.
Intec Pharma’s gastric retentive Accordion Pill™ Carbidopa/
Levodopa
(AP-CD/LD) was being evaluated in a phase 3 study for its safety and efficacy in advanced PD.
Hidden
in
Cure Parkinson's
3 years ago
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