hi all
sci-news.com/medicine/gut-b...
just read this and found it interesting, I definitely have major problems with medication effectiveness and digestive issues. When first diagnosed i had no stomach issues 5 and half years in i have problems with my digestion not initial stomach breakdown of food but digestion through the intestine causes havoc with medication. I wonder if the medication is adding to these problems or even the root cause. My neurologist has never looked into this even though i tell him every time no matter what i eat it brings my slowness n stiffness on, even fruit or a home made vegetable soup avoiding dairy gluten or sugar seems as if any food can trigger it now. wondering if the medication I need is destroying my intestinal biome. Starting to consider bacterial replacement therapy. i was sent to see a gastroenterologist. didn't manage to get a sit down appointment only a phone conversation no tests where done and after a brief phone call i received a letter basically saying he couldn't help. this was all done on the NHS which for my condition i am now realising i can no longer depend on for any real in depth research into my problems they are basically a prescription only service not interested in delving any n further than a diagnosis. I always have struggled with medication efficiency only ever getting around one hour relief from a 125mg Sinemet even less as i have progressed. therefore I'm taking seven Sinemet through the day and one slow release at night alongside usually one or two more instant release to get me through the night otherwise i don't sleep due to stiffness causing me discomfort. unless i basically dont eat anything my medication is basically useless. i know this is a unusually high amount of medication for someone relatively not that far into my life with yopd.
im not that bad with the disease i have no tremor and strugle with only stiffness and slowness of movement when in off state.
im just concerned that my medication while short term relieves these symptoms may be harming me more than anyone realises long term.
my neuro has suggested dbs or the levodopa pump in my stomach but at forty years of age i didn't really want to undergo this type of treatment until absolutely necessary
im taking high dosage thiamine along with most other recommended supplements.