“In 1988, the U.S. Food and Drug Administration (FDA) is recommended that the daily dose of Sinemet should not exceed 800 mg per day, and as of 2013, this recommendation has not been revised. In 2018 the labeling of Sinemet recommends not exceeding a levodopa total daily dose of 2,000 mg per day. As movement disorder specialists, general neurologists and primary care doctors have learned, many people with Parkinson’s can easily tolerate the higher doses used to minimize symptoms. Some people with PD encounter problems with insurance reimbursement of higher daily doses because of the FDA regulation. An insurance decision can be appealed if necessary.”
What is your dose?
C/levodopa 25/100 IR?
One tablet, 2, 3, 3.5? each dose.
Max size is 3.5 tablets. Use the lowest size that works.
By the book you first find single dose that works. Then spacing 3,5,6,8.
Dyskinesia is based on the last single dose size.
It takes 3or4 hours for the dose is used up. If you take another dose too soon, you add to the dose size.