Experiences with

Leucovorin

Hi. I know that breathlessness is a big symptom of B12 deficiency, although I didn't have it at all until I started self-injecting 5 weeks ago. However, my breathlessness seems to be getting worse by the day, and I had to sit outside in the garden for most of today, because I felt like I had real air

Hello, I have been feeling quite unwell with intense fatigue and a myriad of other issues since January 2023. I have sibo and gastritis. My b12 and folate were checked and my folate came back at 2.7 which is low. My b12 however looked ok at around 500. I began to supplement with folinic acid (800mcg

Having been doing quite well I have taken quite a sudden turn of dizziness and cognitive problems over the last 3 days. I am receiving 3 times a week B12 injections along with 5mg folic acid. I have also been taking Thorne Basic B complex. Levothyroxine 100/112.5 alternating. What are the issues and

I'm really getting very low in mood. My tummy heaves constantly. I have been quite proud of myself for about four months because I came off Sertraline. I put this down to my EOD inj of B12. It lifted me so much after nearly 50years on and off, mainly on, antidepressants. I have been worried about my

Hello lovely helpful people, I have a few questions if someone knowledgeable would be so kind to answer please? 1. I'm going to start SI hydroxycobalamin and understand I need a B complex as well as one of the forms of folate supplement. I am opting for folinic acid drops that I can titrate up and

Hello! I've been SI since late 2017, but have changed my co-factor (and other) supplement regime over time - including recently re-introducing folinic acid, having become folate deficient. I've always had low ferritin and months ago started Simply Heme iron supplements, which are supposed to be easier

Hello, I'm looking for some advice on folate levels. I've just got back a set of test results from Thriva, which were generally okay, except that I am now folate deficient (which I've never been before to my knowledge) (result was 6 nmol/L). The reason is obvious to me now, as I made a silly error

hi, I just need to know if it’s ok for me to take my B vitamin complex an hour after T4/T3 with my breakfast. The reason I ask is on the box it states folate - as calcium folinate. I’m now worried if I should leave 4 hours after levo because it mentions calcium? Any help will be appreciated

hi, I take my T4/T3 at least an hour before my breakfast. I take my B12 supplement and Pink Tribe liposomal vitamin B complex liquid just after breakfast. I’ve been reading the ingredients and am worried in case I should be leaving 4 hours for the vitamin B complex due to the folate mentioning calcium

Hello ! 😊 The first step on the B12 💉 now taken - although seeing improvements, with a even twice-a-week frequency may take . . . weeks or months . . . in the case of a v long term medical condition ? So far, not feeling too different either way - & in all, the 1000ug was pretty much a cinch, n⛔

Hi everyone, I have a dilemma. I’ve had 2 B12 jabs in the last 6 months. I tried them because I have been feeling awful and suspected that it may be a deficiency. I suffered from folate deficiency a while back which was treated with folic acid by GP but I felt terrible on it and had to stop. Luckily

Short version: TOO MUCH FOLATE. Taking 5mg folate a day as advised by another group has been making me ill. Has this happened to anyone else? Long version: I have B12D with neuro symptoms. Whether this is functional due to my coeliac disease or a missed PA diagnosis I don’t know. B12 injections

They are now wanting him to do heavy hitting chemo for 6 months, Irinotecan, Fluorouracil and Calcium Leucovorin. I am in the Advanced Prostate Group and wondering what is the best place to get some information on this particular situation. Is it this group?

They said they want to hit it hard with Irinotecan, Flurouracil and Calcium Leucovorin. I see this used for bladder cancer. Can anyone give me some direction what to research and make any sense of this. His wife died, a very good friend 3 years ago.

Folinic acid is an advanced folate in the folate metabolism cycle and is used in mitochondrial respiration, making DNA, and making methylfolate, which is in turn used to make neurotransmitters and to help recycle folate and methyl groups. Folinic acid rather than methylfolate is preferred in these patients

I started cyanocobalamin injections on August 4 2018, almost right away I developed agoraphobia. I am doing the B12 protocol, daily injections, folic acid (5mg), potassium, magnesium glycinate, Bcomplex as well as D3, K2 and zinc. I have not been able to leave my house for nearly 1.5 years. I was in

Patricia Kane protocol Share The Patricia Kane protocol (PK protocol) is an experimental treatment for neurological disease involving intravenous infusion of phospholipids and methylation factors, along with dietary changes and supplements. It is based on the theory that in diseases Kane classes as

Hi all, I am B12 deficient (which was initially suspected in December 2018, following declining health), with prior 6 month history of worsening peripheral neuropathy, worsening exercise intolerance, syncope and frequent pre-syncope and long standing (at least until I started on B12 replacement in December

What milligram of folinic acid should we be taking as a cofactor for B12? I have been taking a B complex pill but not sure if I should just be taking the folinic acid by itself or stick with the B complex.

Hi all Was wondering if anyone with a chemistry bent could explain the difference between folic acid and folinic acid and whether folinic is better than folic for those of us with PA? I've just been to the doctor for my B12 injection and he said that not all of the folic acid is converted, whereas the