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Functional Recovery from Human Induced Pluripotent Stem Cell-Derived Dopamine Neuron Grafts is Dependent on Neurite Outgrowth
Summary Transplantation of human pluripotent stem cell-derived dopaminergic (DA) neurons is an emerging therapeutic strategy for Parkinson’s disease (PD). In this study, we demonstrate, for the first time, that that functional recovery after DA neuron transplant is critically dependent on graft-host
Summary Transplantation of human pluripotent stem cell-derived dopaminergic (DA) neurons is an emerging therapeutic strategy for Parkinson’s disease (PD). In this study, we demonstrate, for the first time, that that functional recovery after DA neuron transplant is critically dependent on graft-host
Farooqji
in
Cure Parkinson's
2 years ago
1Trial of Bradykinesia Stem Cell Therapy Now Dosing Last Group
IMAC Holdings has started dosing the third and final group of participants in a Phase 1 clinical trial assessing the potential of its umbilical cord-derived stem cell therapy for treating bradykinesia, an early motor symptom of Parkinson’s disease characterized by slowness or difficulty in movement.
IMAC Holdings has started dosing the third and final group of participants in a Phase 1 clinical trial assessing the potential of its umbilical cord-derived stem cell therapy for treating bradykinesia, an early motor symptom of Parkinson’s disease characterized by slowness or difficulty in movement.
Farooqji
in
Cure Parkinson's
2 years ago
Alpha fetoprotein test for cirrhosis patients??
Hi, is it standard for this test to be done every 6 months with the liver scan? I've just had my bloods done (post liver scan and pre consultant appointment) and spotted that I have been tested for this for the first time and the results are hidden from my Patient Knows Best account ... should I be worried
Hi, is it standard for this test to be done every 6 months with the liver scan? I've just had my bloods done (post liver scan and pre consultant appointment) and spotted that I have been tested for this for the first time and the results are hidden from my Patient Knows Best account ... should I be worried
teale100
in
British Liver Trust
2 years ago
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Is fibrosis f2 reversible?
Had fibroscan today. Score of 9.2. Is this reversible? I was pleased it wasnt cirrhosis. I was told it was mild fibrosis but online charts indicate f2 as 'significant fibrosis with evidence of progressive liver disease' I have AIH & am taking budesonide 9mg daily. My LFTs have started to normalise so
Had fibroscan today. Score of 9.2. Is this reversible? I was pleased it wasnt cirrhosis. I was told it was mild fibrosis but online charts indicate f2 as 'significant fibrosis with evidence of progressive liver disease' I have AIH & am taking budesonide 9mg daily. My LFTs have started to normalise so
Bigbluemonkey
in
British Liver Trust
2 years ago
Co-supplementation of Vitamin D3, Vitamin K2 MK7 and Calcium
Unless you are actively increasing your Vitamin K2 MK7 levels through diet or supplementation, you are likely deficient and have inadequate levels for your bone and heart health needs. Vitamin K2 MK7 dosage recommendation is 150 to 180 mcg per day. Consult with your physician and a Registered Dietitian
Unless you are actively increasing your Vitamin K2 MK7 levels through diet or supplementation, you are likely deficient and have inadequate levels for your bone and heart health needs. Vitamin K2 MK7 dosage recommendation is 150 to 180 mcg per day. Consult with your physician and a Registered Dietitian
SilentEchoes
in
Cure Parkinson's
2 years ago
News that worried us and studies that gave us hope (04/2022).
This is the information that gave us hope while my father was alive and has given hope to many since then (March 2012). 1. News that worried us. In the coming decades the number of Parkinson's disease patients is feared to increase very worryingly, to double by 2030 (Dorsey 2007) and even to triple
This is the information that gave us hope while my father was alive and has given hope to many since then (March 2012). 1. News that worried us. In the coming decades the number of Parkinson's disease patients is feared to increase very worryingly, to double by 2030 (Dorsey 2007) and even to triple
parkinsonshereandnow
in
Cure Parkinson's
2 years ago
Autoimmune hepatitis 19 year old
Hello to everyone, I'm new here and we got my sons diagnosis yesterday after 5 months of him being unwell and a blood test showing extremely high liver enzyme levels. I wonder if there is anyone ( maybe even of a similar age) with the same condition as I'd really like him to talk to others and I would
Hello to everyone, I'm new here and we got my sons diagnosis yesterday after 5 months of him being unwell and a blood test showing extremely high liver enzyme levels. I wonder if there is anyone ( maybe even of a similar age) with the same condition as I'd really like him to talk to others and I would
MicheleG33
in
British Liver Trust
2 years ago
General introduction and seeking recommendation
Hello All, First of, I want to say how grateful I am for this community. I wish I would have found it much sooner. I’ve been reading through the posts since I joined earlier today and have gained a lot of insightful information. So a little background to my situation. I suspect I’ve had fatty liver
Hello All, First of, I want to say how grateful I am for this community. I wish I would have found it much sooner. I’ve been reading through the posts since I joined earlier today and have gained a lot of insightful information. So a little background to my situation. I suspect I’ve had fatty liver
andrewax2
in
Living with Fatty Liver and NASH
2 years ago
Hello
What's going on? Eventually got a fibroscan on Monday 11/4/22 after badgering my doc as I have just cleared hep c but no follow up. Just a telephone call to say I was clear. This is, of course, brilliant news. However I have been carrying the virus for 35 years. I am 53 now and have symptoms related
What's going on? Eventually got a fibroscan on Monday 11/4/22 after badgering my doc as I have just cleared hep c but no follow up. Just a telephone call to say I was clear. This is, of course, brilliant news. However I have been carrying the virus for 35 years. I am 53 now and have symptoms related
Sharona68
in
British Liver Trust
2 years ago
Red tongue
My hubby has a bright red smooth tongue and inside his bottom lip is really red too. There is no bleeding at all just really red . Is this liver related , thanks
My hubby has a bright red smooth tongue and inside his bottom lip is really red too. There is no bleeding at all just really red . Is this liver related , thanks
Moux1
in
British Liver Trust
2 years ago
IBS general: my experience
Dear all, it's been a while since I posted this, so here it is: This is my general approach to help people understand and repair their gastro-intestinal (GI) performance after being diagnosed with IBS. Firstly, IBS must be diagnosed by your doctor or consultant, after checks and treatment for gastro-intestinal
Dear all, it's been a while since I posted this, so here it is: This is my general approach to help people understand and repair their gastro-intestinal (GI) performance after being diagnosed with IBS. Firstly, IBS must be diagnosed by your doctor or consultant, after checks and treatment for gastro-intestinal
Stuart24
in
IBS Network
2 years ago
Supplement timing
Hey just wanted to check in on timing the following supplements and if you would add any others in or increase the amount. I take 150mg of Levothyroxine in the morning an hour before anything but water. I eat a gluten free diet and am careful about cross contamination. Sadly disnt get tested before
Hey just wanted to check in on timing the following supplements and if you would add any others in or increase the amount. I take 150mg of Levothyroxine in the morning an hour before anything but water. I eat a gluten free diet and am careful about cross contamination. Sadly disnt get tested before
Flowerpot108
in
Thyroid UK
2 years ago
Omicron subvariants: New study gives Evusheld and Sotrovimab the thumbs-up
An in vitro study of several antibody therapies by Japanese researchers found diminished neutralisation of the Omicron variant and particularly of the BA.2 subvariant. Now a study at Washington University indicates that Evusheld and Sotrovimab both retain neutralising activity, while reducing viral load
An in vitro study of several antibody therapies by Japanese researchers found diminished neutralisation of the Omicron variant and particularly of the BA.2 subvariant. Now a study at Washington University indicates that Evusheld and Sotrovimab both retain neutralising activity, while reducing viral load
bennevisplace
in
CLL Support
2 years ago
Should I test? After a tattoo
I recently got my kids names tattooed on my wrist. I went to a clean shop one I’ve been to before and I used vegan ink. I still have this growing fear that came after about hep C and Hep b.
I recently got my kids names tattooed on my wrist. I went to a clean shop one I’ve been to before and I used vegan ink. I still have this growing fear that came after about hep C and Hep b.
mtk0925
in
Liver4Life
2 years ago
Green Tea Polyphenols Attenuated Glutamate Excitotoxicity via Antioxidative and Antiapoptotic Pathways
Neurodegenerative diseases are a wide class of hereditary and sporadic conditions characterized by progressive nervous system dysfunction. These disorders include Alzheimer’s disease (AD), Parkinson’s disease (PD), Huntington’s disease (HD), and amyotrophic lateral sclerosis (ALS) which are caused by
Neurodegenerative diseases are a wide class of hereditary and sporadic conditions characterized by progressive nervous system dysfunction. These disorders include Alzheimer’s disease (AD), Parkinson’s disease (PD), Huntington’s disease (HD), and amyotrophic lateral sclerosis (ALS) which are caused by
SilentEchoes
in
Cure Parkinson's
2 years ago
Pbc after biopsy
Anyone have pbc with mildly raised enzymes and positive asma and iig. Was diagnosed with liver biopsy!
Anyone have pbc with mildly raised enzymes and positive asma and iig. Was diagnosed with liver biopsy!
Casslucy
in
PBC Foundation
2 years ago
Yet another article: Acute hepatitis E virus infection and autoimmune thyroiditis: yet another trigger?
I just found this article, maybe you find it interesting: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3339187/ [EDITED:] Interestingly enough, I once had a
hepatitis
E
infection. I had no clue until a full blood test 2 years ago found antibodies - along with the Hashimoto's diagnosis.
I just found this article, maybe you find it interesting: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3339187/ [EDITED:] Interestingly enough, I once had a
hepatitis
E
infection. I had no clue until a full blood test 2 years ago found antibodies - along with the Hashimoto's diagnosis.
Lunario
in
Thyroid UK
3 years ago
Use of Hep C infected Organs
Hiya partner nrly on transplant list last call on Monday from consultant for consent. Co- ordinators have asked him to read up about receiving a liver with hep C/B has any members got advice or had transplant with this? Thanks
Hiya partner nrly on transplant list last call on Monday from consultant for consent. Co- ordinators have asked him to read up about receiving a liver with hep C/B has any members got advice or had transplant with this? Thanks
Arms-1
in
British Liver Trust
2 years ago
Test results
Taking, levothyroxine 100mg, vit d3/k2 5000iu, selenium 100, magnesium glycinate 500mg.... Inflammation, crp hs.. 1. 0-5 Ferritin... 143. 13-150 Vit.B12.. >150. 37.5-188 Vitd....96.3. 50-200 TSH......0.48. 0.27-4.2 FREE T3......3.59. 3.1-6.8 Free thyroxine.... 16.2. 12-22
Taking, levothyroxine 100mg, vit d3/k2 5000iu, selenium 100, magnesium glycinate 500mg.... Inflammation, crp hs.. 1. 0-5 Ferritin... 143. 13-150 Vit.B12.. >150. 37.5-188 Vitd....96.3. 50-200 TSH......0.48. 0.27-4.2 FREE T3......3.59. 3.1-6.8 Free thyroxine.... 16.2. 12-22
Geegee777
in
Thyroid UK
2 years ago
Researchers report third case of HIV remission after stem cell transplant using umbilical cord blood
A US woman has become the third known person who's gone into HIV remission, and the first mixed-race woman, thanks to a transplant of stem cells from umbilical cord blood, according to research presented at a conference Tuesday. https://edition.cnn.com/2022/02/15/health/hiv-third-person-remission/index.html
A US woman has become the third known person who's gone into HIV remission, and the first mixed-race woman, thanks to a transplant of stem cells from umbilical cord blood, according to research presented at a conference Tuesday. https://edition.cnn.com/2022/02/15/health/hiv-third-person-remission/index.html
Farooqji
in
Cure Parkinson's
2 years ago
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