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Extreme pain in legs
Sorry for yet another post,My husband has decompensated liver cirrhosis and his legs are extremely swollen and he is at the point of not being able to walk now he's in so much pain he also has pain in his lower back, should he go to hospital? If so does anyone know what they will do?
Sorry for yet another post,My husband has decompensated liver cirrhosis and his legs are extremely swollen and he is at the point of not being able to walk now he's in so much pain he also has pain in his lower back, should he go to hospital? If so does anyone know what they will do?
Hithereeveryone
in
British Liver Trust
3 months ago
Phase 1/2 of TLX592 Targeted Alpha Therapy in Prostate Cancer starting soon - Ac 225
"The approach accelerates blood clearance and reduces bone marrow residence time compared with standard monoclonal antibodies (mAbs), while retaining target selectivity, internalisation and retention." https://www.prnewswire.com/news-releases/telix-completes-proof-of-concept-study-of-tlx592-targeted-alpha-therapy-in-prostate-cancer
"The approach accelerates blood clearance and reduces bone marrow residence time compared with standard monoclonal antibodies (mAbs), while retaining target selectivity, internalisation and retention." https://www.prnewswire.com/news-releases/telix-completes-proof-of-concept-study-of-tlx592-targeted-alpha-therapy-in-prostate-cancer
Maxone73
in
Advanced Prostate Cancer
3 months ago
Psychological and fitness assessment form
Hi, I’m filling in my transplant assessment form for a meeting in a few weeks time and some of the questions seem vague. There is a question regarding how healthy I feel today with a scale from 1 to 10 ( eq5d ). Does this refer to mental, physical or general health ? Also , if you say you feel too
Hi, I’m filling in my transplant assessment form for a meeting in a few weeks time and some of the questions seem vague. There is a question regarding how healthy I feel today with a scale from 1 to 10 ( eq5d ). Does this refer to mental, physical or general health ? Also , if you say you feel too
Bootsforlife
in
British Liver Trust
3 months ago
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borderline renal function, my MD cut my Nubeqa in half--thoughts?
Borderline renal function, mets to pelvis, and multiple lymph nodes in lungs, but seen only on PET, not on MRI . age 83
Borderline renal function, mets to pelvis, and multiple lymph nodes in lungs, but seen only on PET, not on MRI . age 83
Sweetjessie
in
Advanced Prostate Cancer
3 months ago
FREE Arthritis Self-Management Event
I thought some of you may be interested in this event on Wed 6th March, 6.00pm (GMT); its aimed at young people or anyone supporting a young person with arthritis. Tickets can be booked here: https://www.eventbrite.co.uk/e/arthritis-me-tickets-811392285167 Ann Arthritis Action Comms Team,
I thought some of you may be interested in this event on Wed 6th March, 6.00pm (GMT); its aimed at young people or anyone supporting a young person with arthritis. Tickets can be booked here: https://www.eventbrite.co.uk/e/arthritis-me-tickets-811392285167 Ann Arthritis Action Comms Team,
arthritis_action
Partner
in
Arthritis Action
6 months ago
Ped5i/Tadalafil etc as a benefit to SE of ADT?
Tadalafil , etc is prescribed for ED, BPH and PAH (pulmonary arterial hypertension). It is pretty much agreed upon that Tadalafil increases insulin sensitivity thus improving lean body mass, particularly around the gut, improves Testosterone/estrogen relationship and is good for heart and vascular health
Tadalafil , etc is prescribed for ED, BPH and PAH (pulmonary arterial hypertension). It is pretty much agreed upon that Tadalafil increases insulin sensitivity thus improving lean body mass, particularly around the gut, improves Testosterone/estrogen relationship and is good for heart and vascular health
pj1121
in
Advanced Prostate Cancer
3 months ago
UTI Treatment
Can someone please tell me what antibiotic might be best fo a water infection. I'm so worried about a bad reaction since that's what I got with taking Nitrofurantoin.Thank you.
Can someone please tell me what antibiotic might be best fo a water infection. I'm so worried about a bad reaction since that's what I got with taking Nitrofurantoin.Thank you.
3rdNettydoon
in
Pernicious Anaemia Society
3 months ago
THC , CBD
hi During my annual swaree down to South Africa , I came across a health guru, advised Me to try THC , the only problem is I’m about to finish my small bottle , I’ve been putting couple of drops under my tongue when my off period starts after madopar , why are we so stuck up in the uk , with all these
hi During my annual swaree down to South Africa , I came across a health guru, advised Me to try THC , the only problem is I’m about to finish my small bottle , I’ve been putting couple of drops under my tongue when my off period starts after madopar , why are we so stuck up in the uk , with all these
Troongolfer
in
Cure Parkinson's
3 months ago
Kidney stones?
Morning everyone, just wondered if anyone has had kidney stones. I have been experiencing pain in my left groin and lower back and side for a few weeks. It wakes me up at night and l get it intermittently through the day. The doctor thinks it maybe Arthritis and l am getting a xray on Thursday. What
Morning everyone, just wondered if anyone has had kidney stones. I have been experiencing pain in my left groin and lower back and side for a few weeks. It wakes me up at night and l get it intermittently through the day. The doctor thinks it maybe Arthritis and l am getting a xray on Thursday. What
70michael
in
Lung Conditions Community Forum
3 months ago
Causes of Afib
I have a question: One of the programs available at the HealthUnlocked "my hub" site from the AFA is entitled: "Atrial Fibrillation and You" It lists common causes of Afib: High blood pressure Coronary heart disease Mitral valve disease (caused by rheumatic heart disease, valve problems at birth
I have a question: One of the programs available at the HealthUnlocked "my hub" site from the AFA is entitled: "Atrial Fibrillation and You" It lists common causes of Afib: High blood pressure Coronary heart disease Mitral valve disease (caused by rheumatic heart disease, valve problems at birth
fibnum
in
AF Association
7 months ago
BLA for Subcutaneous Nivolumab Accepted by the FDA for Advanced/Metastatic Solid Tumors
A biologics license application (BLA) has been accepted by the FDA seeking approval of nivolumab (Opdivo) co-formulated with Halozyme’s proprietary recombinant human hyaluronidase (rHuPH20; subcutaneous nivolumab) for adult patients with solid tumors eligible for previously approved nivolumab indications
A biologics license application (BLA) has been accepted by the FDA seeking approval of nivolumab (Opdivo) co-formulated with Halozyme’s proprietary recombinant human hyaluronidase (rHuPH20; subcutaneous nivolumab) for adult patients with solid tumors eligible for previously approved nivolumab indications
God_Loves_Me
in
Advanced Prostate Cancer
3 months ago
Redefining Parkinson's Disease | Kathleen Poston Podcast
I seldom listen to podcasts. I was never sure why. Eventually decided it was just too hard to retain new information. But this one should stay in my brain. She talks about the triad of symptoms that define PD: 1. Bradykinesia 2. Stiffness and 3. Tremor. And then the dozen of other
I seldom listen to podcasts. I was never sure why. Eventually decided it was just too hard to retain new information. But this one should stay in my brain. She talks about the triad of symptoms that define PD: 1. Bradykinesia 2. Stiffness and 3. Tremor. And then the dozen of other
kaypeeoh
in
Cure Parkinson's
3 months ago
Study Offers New Clues to Why Most People with Autoimmune Diseases Are Women
[i]Caption:[/i] [i]Purple chromosomes fill the scene but a greyed-out chromosome locked up with chains labeled "Xist" is in the foreground. One of the Xist chains is covered with sharp thorns.[/i] [i]Xist molecules shut down one of two female X chromosomes to avoid toxic protein levels, but they
[i]Caption:[/i] [i]Purple chromosomes fill the scene but a greyed-out chromosome locked up with chains labeled "Xist" is in the foreground. One of the Xist chains is covered with sharp thorns.[/i] [i]Xist molecules shut down one of two female X chromosomes to avoid toxic protein levels, but they
helvella
Thyroid UK
in
Thyroid UK
6 months ago
Mikemike
Hello....I am here and happy to help in any way I can. Will try to be concise. G-9...radiation only(28 sessions IMRT) a breeze. Declined lupron...because of a continuing anxiety condition. Metastices showed up 14 most later...PSA 6.7 up to 16.2 in 6 weeks. PSMA pet showed two rib mets and 1 other on
Hello....I am here and happy to help in any way I can. Will try to be concise. G-9...radiation only(28 sessions IMRT) a breeze. Declined lupron...because of a continuing anxiety condition. Metastices showed up 14 most later...PSA 6.7 up to 16.2 in 6 weeks. PSMA pet showed two rib mets and 1 other on
Poppy1952
in
Advanced Prostate Cancer
3 months ago
got tested
hello, today I got following tests, ast, alt, bilirubin, ggt, leuktocytes, hemoglobin and all were normal now . then I assume that my so-called symptoms are not due to decompensated liver cirrhosis.. or how were your blood tests at diagnosis/symptoms (fatigue, spider nevi)(?) ☀️☀️
hello, today I got following tests, ast, alt, bilirubin, ggt, leuktocytes, hemoglobin and all were normal now . then I assume that my so-called symptoms are not due to decompensated liver cirrhosis.. or how were your blood tests at diagnosis/symptoms (fatigue, spider nevi)(?) ☀️☀️
Spider2
in
British Liver Trust
3 months ago
Utis and clear urine.
I dont think conventional wisdom is the answer to my question.Every six weeks i get my sp catheter changed. When the doc changed it in the cystoscopy room, twice i had clear urine and no utis. Anywhere else with that doc or nurse, i get utis and or muddy urine. I say the air is filtered better in that
I dont think conventional wisdom is the answer to my question.Every six weeks i get my sp catheter changed. When the doc changed it in the cystoscopy room, twice i had clear urine and no utis. Anywhere else with that doc or nurse, i get utis and or muddy urine. I say the air is filtered better in that
Tempa
in
Men's Health Forum
3 months ago
Jevtana
Once again I am asking for any information that can be provided from this great group. Would appreciate any information for Jevtana treatment. At doctor's appt yesterday, my husband's hemoglobin had decreased to 7.6 and he had to have a blood transfusion. His Alkaline Phosphatase went up again. He
Once again I am asking for any information that can be provided from this great group. Would appreciate any information for Jevtana treatment. At doctor's appt yesterday, my husband's hemoglobin had decreased to 7.6 and he had to have a blood transfusion. His Alkaline Phosphatase went up again. He
MsHope
in
Advanced Prostate Cancer
3 months ago
Targeting the glutamine metabolism to suppress cell proliferation in mesenchymal docetaxel-resistant prostate cancer
Source Link : https://www.nature.com/articles/s41388-024-03059-4 Docetaxel (DX) serves as a palliative treatment option for metastatic prostate cancer (PCa). Despite initial remission, acquired DX resistance is inevitable. The mechanisms behind DX resistance have not yet been deciphered, but a mesenchymal
Source Link : https://www.nature.com/articles/s41388-024-03059-4 Docetaxel (DX) serves as a palliative treatment option for metastatic prostate cancer (PCa). Despite initial remission, acquired DX resistance is inevitable. The mechanisms behind DX resistance have not yet been deciphered, but a mesenchymal
God_Loves_Me
in
Advanced Prostate Cancer
3 months ago
Putting on weight
I have under thyroid and have posted a few questions so sorry for another one. Do any if you find if you put on the slightest but of weight it triggers you to go more underactive? For example at Xmas like most people I put on a bit of weight then I feel I go underactive and then put on more weight.
I have under thyroid and have posted a few questions so sorry for another one. Do any if you find if you put on the slightest but of weight it triggers you to go more underactive? For example at Xmas like most people I put on a bit of weight then I feel I go underactive and then put on more weight.
Billy2023
in
Thyroid UK
6 months ago
RO 52 Positive
I have tested positive for isolated RO52 antibodies. ANA negative. I have Raynaud's, rashes, splinter hemorrages, tiredness, breathlessness on exertion, (ground glass opacities in lungs, waiting on a second CT) joint aches, mild gastro issues. Am I likely to have Lupus primarily, or some other autoimmune
I have tested positive for isolated RO52 antibodies. ANA negative. I have Raynaud's, rashes, splinter hemorrages, tiredness, breathlessness on exertion, (ground glass opacities in lungs, waiting on a second CT) joint aches, mild gastro issues. Am I likely to have Lupus primarily, or some other autoimmune
Graysonfur
in
LUPUS UK
6 months ago
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