Once again I am asking for any information that can be provided from this great group.
Would appreciate any information for Jevtana treatment.
At doctor's appt yesterday, my husband's hemoglobin had decreased to 7.6 and he had to have a blood transfusion. His Alkaline Phosphatase went up again.
He will start on Jevtana on June 20th. We are hoping this will do him some good.
My husband's Oncologist sent an order 6 weeks ago for him to start Pluvicto. The only treatment center in Houston. The Oncologist in Houston called last week and told us my husband couldn't have Pluvicto treatment because his Hemoglobin (8.6) was too low, Then another person from treatment center in Houston called and said he could get treatment. So we don't know what is going on.
We contacted his Oncologist in Victoria, Tx. which has been treating him for over 5 years. The PA said they were not aware of the issue of Pluvicto treatment with low hemoglobin. Which they should!!! Then Pa starts talking about treating him with another chemotherapy called Jevtana instead of Pluvicto. That was not even discussed with his Doctor at the last visit. His Oncologist insisted on him taking chemo using Taxotere which he took 6 rounds of treatment. It did not work as well as expected. This was so he would qualify for Pluvicto treatment.
Thank you in advance for any replies.
Would appreciate any replies regarding Pluvicto treatments and side effects.
Yesterday had follow up appointment with his oncologist to go over scan results.
Doctor said obviously the Docetaxel did work some but not enough.
Next treatment will be Pluvicto.
My husband had his first chemo treatment of 275ml Docetaxel (Taxotere) on 1/11/24 and his 6th and last treatment 4/21/24.
My husband had his PSMA PET/CT last week and overall it was good.
Right frontal skull SUV 5.3 previously 0.75, C3 SUV 22 previously 13.9, right clavicle 9.23 previously 23.6 clavicle 3.0 previously 13.0 left humeral head 32 previously 36.3 right humeral head 10.3 previously 18.6, sternum 21.2, previously 31, L1 25
previously 31.2, sacrum 24.3 previously 34.6, Left anterior trochanteric femoral activity SUV 24 previously 23.5 - the volume involved has increased.
Last month my husband's PSA decreased 1144 points to 586. This month it increased to 1658.968 NG/ML. 1072 point increase. This is difficult to believe the difference.
Thank you in advance for any information you can provide
Written by
MsHope
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I saw one reply to your post. It appeared to describe a good many negative side affects to Pluvicto. Here are highlights of my post in March, summarizing our experience of the treatment:
He’s spent the last two years “living” in the recliner in the living room. Pneumonia 3 times: a collapsed lung, likely from one of a series of falls last spring. On oxygen PRN since June 2023.
Surgery to stretch the right lung was completed in November 2023. Steady improvement since then.
Finished 6th dose of Pluvicto in February 2024. PSA <.05! Bone mets and lung tumors shrunk. Radiologist reading report says successful treatment. Uptake in liver and spleen.
Side effects included a general feeling of malaise and extreme fatigue at about day 3 post-infusion. That’s it. No more or less pain than prior to treatment….just really tired. So he slept!!
We’re in our second week of vacation in Florida, where my Joe is sunning and swimming, biking, and hitting tennis balls!!!!
Three times over the last two years I was certain the end was near. Joe’s rebound is nothing short of miraculous!
I have no idea what mutations are/mean. His oncologist has never mentioned this. Where would that info be and what are the differences?
My husband completed 4 rounds of Pluvicto, December 2023 - April 2024. Treatment stopped after 4 rounds as some areas of cancer were progressing. During the treatment time, scans showed that many areas of lymph nodes and bone mets declined significantly; prostate uptake shrunk significantly, etc. In these areas, the path reports described the results as "near resolved." However in some lymph nodes they saw growth, and a few new bone mets. So our view is Pluvicto had a significant positive impact but now time to throw something else at the cancer.
Side effects of treatment: Fatigue for 2-3 days. Nausea well-controlled with meds. Dry mouth began after second treatment; Biotene and sugarless candy helped. Overall the side effects were significantly easier to manage than chemo.
Benefits: In addition to the impact on tumor avidity, his pain declined significantly during this treatment, and the interim periods between treatment offered very positive quality of life.
My husband has had 2 Pluvicto treatments. The chemo didn't work very well for him either. After 2 treatments his PSA dropped from 95 to 16. He has low energy but is in no pain now.
I have read that you cannot be close to a person for a day after Pluvicto due to the radiation. To minimize radiation exposure to others, advise patients to limit close contact (less than 3 feet) with household contacts for 2 days. What info were you given regarding this. This is impossible to do, since we have to drive to Houston and be in truck together. There is no way to be less then 3 feet.
We have a SUV. I drive him home. He sits in the back of the SUV opposite me. We have only one bathroom so he is supposed to flush twice after each use. I wash our clothes separately including bedding and towels for about 7 days just to be on the safe side and wear plastic gloves when cleaning the bathroom. Does your truck have a back seat?
Thanks for your reply. We have a F250 Ram Truck and it does have a back seat, but not 3ft away from front driver seat. Do you still sleep in same bed after treatment. Also we have a dog and he always sits with my husband in recliner.
We do not sleep together after his treatment and it would be best for your dog not to be that close to him. Our SUV is not 3 feet apart but it is the best we can do.
How long did it take for your husband to get approved for Pluvicto and start treatments? I has been over 2 weeks since my husbands Onocologist advised him that he was going to get him on Pluvicto.
I have completed six Pluvicto treatments with good results, and am looking forward to better outcomes than chemo. Each person reacts differently to any treatment. Below video might help your understanding.
Hi. Just completed my 6th Pluvicto infusion 2 weeks ago. My side effects were very dry mouth, intermittent diarrhea and a noticeable loss of appetite, which was appreciated. The dry mouth has been the most uncomfortable but overall it sure beats the alternative. I’m glad to have had the opportunity to receive the treatments and the initial scans show my mets are “resolving”. Good luck to your hubby and God bless!
Yes. I slept in the guest room and we kept three feet apart unless we were just passing each other quickly. No hugs or kisses for three days. That was tough but it passed quickly and our friends had fun joking about my glowing personality.
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