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BLA for Subcutaneous Nivolumab Accepted by the FDA for Advanced/Metastatic Solid Tumors
A biologics license application (BLA) has been accepted by the FDA seeking approval of nivolumab (Opdivo) co-formulated with Halozyme’s proprietary recombinant human hyaluronidase (rHuPH20; subcutaneous nivolumab) for adult patients with solid tumors eligible for previously approved nivolumab indications
A biologics license application (BLA) has been accepted by the FDA seeking approval of nivolumab (Opdivo) co-formulated with Halozyme’s proprietary recombinant human hyaluronidase (rHuPH20; subcutaneous nivolumab) for adult patients with solid tumors eligible for previously approved nivolumab indications
God_Loves_Me
in
Advanced Prostate Cancer
1 month ago
bilirubin
i have pbc/aih …. my 3 monthly blood test is back and the bilirubin levels are way up ….. just wondering if anyone knows what this may indicate?
i have pbc/aih …. my 3 monthly blood test is back and the bilirubin levels are way up ….. just wondering if anyone knows what this may indicate?
She-66
in
PBC Foundation
7 months ago
stress related relapse?
Hi All. Down to 6mgs Pred for GCA/ PMR. was doing well with rest and exercise and then hubby had double bypass operation just over two weeks ago. Am now getting the odd sharp pain in the temples about once a day. Really sharp. Wondering if I should go back up to 10 mgs for a week or two. Really hate
Hi All. Down to 6mgs Pred for GCA/ PMR. was doing well with rest and exercise and then hubby had double bypass operation just over two weeks ago. Am now getting the odd sharp pain in the temples about once a day. Really sharp. Wondering if I should go back up to 10 mgs for a week or two. Really hate
CathyMeg
in
PMRGCAuk
4 months ago
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vitamin d advice please
I’m sub clinic apparently. I plan to start V D but my first look at what’s available is confusing. Is there more than one V D as I see some are called D3? Is the RDA amount available or do you just take lots to make it up. I’m 61 female with AI rheumatoid conditions and veggie.
I’m sub clinic apparently. I plan to start V D but my first look at what’s available is confusing. Is there more than one V D as I see some are called D3? Is the RDA amount available or do you just take lots to make it up. I’m 61 female with AI rheumatoid conditions and veggie.
Stills
in
Thyroid UK
5 months ago
here we go again😬
after 8 long months I finally summoned up the courage to run again. Long story short I had an op beg of last August, not allowed to run for 3 months, enforced sitting around aggravated my GTS, and then after physio for that I developed a painful/ weak ankle on the other side so more physio. Finally
after 8 long months I finally summoned up the courage to run again. Long story short I had an op beg of last August, not allowed to run for 3 months, enforced sitting around aggravated my GTS, and then after physio for that I developed a painful/ weak ankle on the other side so more physio. Finally
limberlou
Graduate
in
Couch to 5K
4 months ago
Seafood shows promise as a future Parkinson's disease medication
Perhaps as a future PD medication, but nothing prevents you from enjoying seafood in your (MIND) diet already! From the Science News Team of the Dutch Parkinson's association I read the following article. [i]There is limited knowledge about the role of substances derived from marine life in the
Perhaps as a future PD medication, but nothing prevents you from enjoying seafood in your (MIND) diet already! From the Science News Team of the Dutch Parkinson's association I read the following article. [i]There is limited knowledge about the role of substances derived from marine life in the
Esperanto
in
Cure Parkinson's
8 months ago
is this a lupus rash?
Just wanted to add: I’m not taking anything anyone says as a diagnosis or medical advice I promise. I was just curious what people thought it looked like, and just gave info for context. I promise I’m not thinking if someone says it does look like the lupus rash that I’m not taking it as a diagnosis
Just wanted to add: I’m not taking anything anyone says as a diagnosis or medical advice I promise. I was just curious what people thought it looked like, and just gave info for context. I promise I’m not thinking if someone says it does look like the lupus rash that I’m not taking it as a diagnosis
Lostnthought00
in
LUPUS UK
5 months ago
Cholesterol, pred and PMR?
Hi. I recently joined "Our Future Health" it's a project to get DNA profiles of 5 million people in UK , in order to get a detailed picture.of the nation's health...put in very simple terms. Joining involves completing a questionnaire and an appointment wher you are weighed, measured, BP, heart rate
Hi. I recently joined "Our Future Health" it's a project to get DNA profiles of 5 million people in UK , in order to get a detailed picture.of the nation's health...put in very simple terms. Joining involves completing a questionnaire and an appointment wher you are weighed, measured, BP, heart rate
MamaBeagle
in
PMRGCAuk
4 months ago
Finally passed a kt/v test
Ok, so after 11 months, I finally passed my kt/v test with a score of 1.82, which my nurse said is passing for PD patients. Initially I was on 8 hours, 4 exchanges of 1800ml per night. When I failed the first test, then they moved me to 2000ml per exchange, then 10 hours of 5 exchanges of 2000ml, then
Ok, so after 11 months, I finally passed my kt/v test with a score of 1.82, which my nurse said is passing for PD patients. Initially I was on 8 hours, 4 exchanges of 1800ml per night. When I failed the first test, then they moved me to 2000ml per exchange, then 10 hours of 5 exchanges of 2000ml, then
RonZone
in
Kidney Dialysis
8 months ago
Can Nubeqa (Darolutamide) be used instead of normal ADT drugs for localized PCa?
Hi all. Australia has just given the green light to lower the cost of this so-called wonder drug from a staggering $40K (AUD) to a low $30. It seems that this drug has fewer side effects than the usual ADT drugs and from what I can gather does a pretty good job of preventing the growth and spread
Hi all. Australia has just given the green light to lower the cost of this so-called wonder drug from a staggering $40K (AUD) to a low $30. It seems that this drug has fewer side effects than the usual ADT drugs and from what I can gather does a pretty good job of preventing the growth and spread
Mike58
in
Advanced Prostate Cancer
8 months ago
New blood pressure procedure is ‘game-changing’ for people with uncontrolled hypertension, say doctors
New blood pressure procedure is ‘game-changing’ for people with uncontrolled hypertension, say doctors. Procedure reduces blood pressure without medications, say experts:‘Important step forward’ People with treatment-resistant hypertension could benefit from a new procedure that the FDA recently approved
New blood pressure procedure is ‘game-changing’ for people with uncontrolled hypertension, say doctors. Procedure reduces blood pressure without medications, say experts:‘Important step forward’ People with treatment-resistant hypertension could benefit from a new procedure that the FDA recently approved
lupus-support1
Administrator
in
LUpus Patients Understanding and Support
6 months ago
Fibroscan CAP scores
There are a few things that I don’t understand about Fibroscan CAP scores. I have looked at the NICE 49 full guideline which can be found here: https://www.nice.org.uk/guidance/ng49/evidence/full-guideline-pdf-2548213310 Fibroscan CAP scores are discussed in detail on pages 62 to 74; the CAP scores
There are a few things that I don’t understand about Fibroscan CAP scores. I have looked at the NICE 49 full guideline which can be found here: https://www.nice.org.uk/guidance/ng49/evidence/full-guideline-pdf-2548213310 Fibroscan CAP scores are discussed in detail on pages 62 to 74; the CAP scores
mickeymouse42
in
British Liver Trust
8 months ago
Very low blood pressure
Hi again, I went for a recorder loop implant today, which I was quite relaxed in doing. I did go by taxi just in case, but felt quite unsteady in walking to reception. This was no worse than the Saturday just gone, when I checked in at A&E as I felt pretty unsteady also ( they found nothing by the
Hi again, I went for a recorder loop implant today, which I was quite relaxed in doing. I did go by taxi just in case, but felt quite unsteady in walking to reception. This was no worse than the Saturday just gone, when I checked in at A&E as I felt pretty unsteady also ( they found nothing by the
Quovadisuk
in
Atrial Fibrillation Support
4 months ago
Are you joining us for our Patient Day in Baltimore, taking place on Saturday March 02?
There is still time to register for this
FREE
event, so do not delay and miss out on the unique opportunity to meet local medical experts to find out more about your heart health and in particular, heart rhythm conditions, such as atrial fibrillation and much more! You will also have the chance
There is still time to register for this
FREE
event, so do not delay and miss out on the unique opportunity to meet local medical experts to find out more about your heart health and in particular, heart rhythm conditions, such as atrial fibrillation and much more! You will also have the chance
TracyAdmin
Partner
in
AF Association
4 months ago
Are you joining us for our Patient Day in Baltimore, taking place on Saturday March 02?
There is still time to register for this FREE event, so do not delay and miss out on the unique opportunity to meet local medical experts to find out more about your heart health and in particular, heart rhythm conditions, such as supraventricular, atrial fibrillation and much more! You will also
There is still time to register for this FREE event, so do not delay and miss out on the unique opportunity to meet local medical experts to find out more about your heart health and in particular, heart rhythm conditions, such as supraventricular, atrial fibrillation and much more! You will also
TracyAdmin
Partner
in
Sudden Cardiac Arrest & Heart Attack
4 months ago
Are you joining us for our Patient Day in Baltimore, taking place on Saturday March 02?
There is still time to register for this FREE event, so do not delay and miss out on the unique opportunity to meet local medical experts to find out more about your heart health and in particular, heart rhythm conditions, such as supraventricular, atrial fibrillation and much more! You will also
There is still time to register for this FREE event, so do not delay and miss out on the unique opportunity to meet local medical experts to find out more about your heart health and in particular, heart rhythm conditions, such as supraventricular, atrial fibrillation and much more! You will also
TracyAdmin
ArrhythmiaAlliance
in
Arrhythmia Alliance
4 months ago
Atrial Fibrillation Association Patients Day On-Demand now!
Atrial Fibrillation Association Patients Day On-Demand now! Heart racing? Palpitations? Breathlessness? How do you manage living with AF? Join us from the comfort of your home to hear from medical experts in AF. You will be able to manage living with AF so much better after watching these presentations
Atrial Fibrillation Association Patients Day On-Demand now! Heart racing? Palpitations? Breathlessness? How do you manage living with AF? Join us from the comfort of your home to hear from medical experts in AF. You will be able to manage living with AF so much better after watching these presentations
TracyAdmin
Partner
in
AF Association
4 months ago
niacin as cause of strokes and heart attacks?
I know a lot of us taking B Complex so posting this article to hear your thoughts. I take one from cytoplasm where it’s 16mg, I wonder if this is ok 🤔 https://www.newscientist.com/article/2417665-niacin-supplements-linked-to-greater-risk-of-heart-attacks-and-strokes/ [ Link edited to remove potentially
I know a lot of us taking B Complex so posting this article to hear your thoughts. I take one from cytoplasm where it’s 16mg, I wonder if this is ok 🤔 https://www.newscientist.com/article/2417665-niacin-supplements-linked-to-greater-risk-of-heart-attacks-and-strokes/ [ Link edited to remove potentially
Kari55
in
Thyroid UK
4 months ago
relief from arthritis while taking apaxiban
reccomendations to relieve arthritis in lower back and hips - I’m taking apaxiban and have been advised against ibuprofen - many thanks Michael John
reccomendations to relieve arthritis in lower back and hips - I’m taking apaxiban and have been advised against ibuprofen - many thanks Michael John
Spinbiker
in
Arthritis Action
5 months ago
Nose sores
Good morning, Can anyone tell me what you do for nose sores. I've had one at the inside tip for weeks. They come and go but when they come they last for weeks. They've been coming more frequently too. I'm at a loss of how to heal this. I was diagnosed with Lupus SLE, Sjogren's and MCTD. Is it
Good morning, Can anyone tell me what you do for nose sores. I've had one at the inside tip for weeks. They come and go but when they come they last for weeks. They've been coming more frequently too. I'm at a loss of how to heal this. I was diagnosed with Lupus SLE, Sjogren's and MCTD. Is it
Tessie62
in
NRAS
5 months ago
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