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New knowledge about neuroendocrine prostate cancer
CDC7, I have always hated that guy since I watched Star Wars...or was it another guy? "These results nominate CDC7 inhibition as a therapeutic strategy to constrain lineage plasticity, as well as to effectively treat NE tumors de novo or after transformation. As simurosertib clinical efficacy trials
CDC7, I have always hated that guy since I watched Star Wars...or was it another guy? "These results nominate CDC7 inhibition as a therapeutic strategy to constrain lineage plasticity, as well as to effectively treat NE tumors de novo or after transformation. As simurosertib clinical efficacy trials
Maxone73
in
Advanced Prostate Cancer
22 days ago
Diagnosed 4+3
Hello all, Yesterday I was diagnosed with prostate cancer & would appreciate any guidance. Awaiting to be scheduled for PSMA PET Scan PSA 18.987 MRI - 1 Lesion 9mm Pathology: 4+3 A. Right Posterior Medial Adenocarcinoma; Gleason Score 6(3+3); Grade Group 1; Tumor measures 8 mm
Hello all, Yesterday I was diagnosed with prostate cancer & would appreciate any guidance. Awaiting to be scheduled for PSMA PET Scan PSA 18.987 MRI - 1 Lesion 9mm Pathology: 4+3 A. Right Posterior Medial Adenocarcinoma; Gleason Score 6(3+3); Grade Group 1; Tumor measures 8 mm
bl2307
in
Prostate Cancer Network
22 days ago
yoday
went to surgeon for consult. I enjoyed talking to him and his candor. I was told by him radiation treatment would be better choice due to complications for two other surgery's. i have had bowel resection and hernia sergery with mesh. We called the radiologist to get things going with him. Need to
went to surgeon for consult. I enjoyed talking to him and his candor. I was told by him radiation treatment would be better choice due to complications for two other surgery's. i have had bowel resection and hernia sergery with mesh. We called the radiologist to get things going with him. Need to
Laguy01
in
Prostate Cancer Network
22 days ago
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Verzenio alone
I was wondering if anyone has used Verzenio after Ibrance and Fulvestrant have failed? I did get a couple good years on the Ibrance/Fulvestrant I am ER+ HR- and have used all my hormone treatment options and am facing IV Chemo. However my Dr. says Verzenio may be an option. ‘Thanks for any encouraging
I was wondering if anyone has used Verzenio after Ibrance and Fulvestrant have failed? I did get a couple good years on the Ibrance/Fulvestrant I am ER+ HR- and have used all my hormone treatment options and am facing IV Chemo. However my Dr. says Verzenio may be an option. ‘Thanks for any encouraging
DinNorCal
in
SHARE Metastatic Breast Cancer
22 days ago
Preparation for mammogram
I’ve had an appointment letter for my first mammogram. Always been apprehensive about this as heard it’s painful and know lady who needed physiotherapy on her shoulder afterwards. I have PMR to contend with now and whilst the afternoon slot should help, wondered if there is anything I can do make
I’ve had an appointment letter for my first mammogram. Always been apprehensive about this as heard it’s painful and know lady who needed physiotherapy on her shoulder afterwards. I have PMR to contend with now and whilst the afternoon slot should help, wondered if there is anything I can do make
Body_bonkers
in
PMRGCAuk
23 days ago
side effects
i have prostate cancer with gleson scale of 8. Trying to figure out if radiation or surgery is the best course of action. Can any body talk about their experiences with erectial issues and inconsonance. I am 58 and looking st the future.
i have prostate cancer with gleson scale of 8. Trying to figure out if radiation or surgery is the best course of action. Can any body talk about their experiences with erectial issues and inconsonance. I am 58 and looking st the future.
Laguy01
in
Prostate Cancer Network
23 days ago
mr. Smith
just got diagnosed with prostate cancer with gleson scale of 8. I have had CAT scan and bone scan, they came back good. My urologist is suggesting surgery or possibly surgery, radiation and hormone therapy. The radiologist says proton or IMTR radiation plus hormone treatment. I have appointment to
just got diagnosed with prostate cancer with gleson scale of 8. I have had CAT scan and bone scan, they came back good. My urologist is suggesting surgery or possibly surgery, radiation and hormone therapy. The radiologist says proton or IMTR radiation plus hormone treatment. I have appointment to
Laguy01
in
Prostate Cancer Network
23 days ago
And breathe …..
On a blood test from my GP 3 weeks ago the results showed blasts, where previously I hadn’t had any. Obviously this caused me a great deal of worry. I had blood taken on Tuesday and spoke to haematologist this afternoon. He said he’d looked at the blood film on both tests himself and couldn’t see anything
On a blood test from my GP 3 weeks ago the results showed blasts, where previously I hadn’t had any. Obviously this caused me a great deal of worry. I had blood taken on Tuesday and spoke to haematologist this afternoon. He said he’d looked at the blood film on both tests himself and couldn’t see anything
lizzziep
in
MPN Voice
24 days ago
Post Chemo Scan Consultation - Good News
Hello wonderful women I saw the Oncologist yesterday, 5 weeks after my post chemo scan, which was clear! What a long time to wait! Some ladies will know that I was staged at 2B because they were concerned that it was cancer cells making the ovary stick to the sigmoid colon. But 'pathologically' the
Hello wonderful women I saw the Oncologist yesterday, 5 weeks after my post chemo scan, which was clear! What a long time to wait! Some ladies will know that I was staged at 2B because they were concerned that it was cancer cells making the ovary stick to the sigmoid colon. But 'pathologically' the
Emcee71
in
My Ovacome
24 days ago
CT scan
My CT scan is showing metastases of lung, heart and liver, and suspicious lymph nodes! I’m currently on Faslodex for three years for right Lung Tumor from MBC. Please pray for a miracle! God bless all of you ladies! I see the oncologist on Friday. Susie
My CT scan is showing metastases of lung, heart and liver, and suspicious lymph nodes! I’m currently on Faslodex for three years for right Lung Tumor from MBC. Please pray for a miracle! God bless all of you ladies! I see the oncologist on Friday. Susie
Likes
in
SHARE Metastatic Breast Cancer
24 days ago
cocoacandy
Being treated for metastatic breast cancer with monthly injections of Faslodex . I have the pungent oder ( as I call it ) for at least a week after the injections . Like many others on here the doctor said they never heard of this symptom . I am wondering how others with it are describing the smell
Being treated for metastatic breast cancer with monthly injections of Faslodex . I have the pungent oder ( as I call it ) for at least a week after the injections . Like many others on here the doctor said they never heard of this symptom . I am wondering how others with it are describing the smell
Cocoacandy
in
SHARE Metastatic Breast Cancer
24 days ago
Rant warning......
Morning my friends. So I had an appointment at the kellgren centre last week a follow up on last year. Went well came out with a plan for my local rheumy which was nerve tests on feet due to altered sensation, chase up over due dexa scan and to start tacrolimus. Bloods and urine were done with the results
Morning my friends. So I had an appointment at the kellgren centre last week a follow up on last year. Went well came out with a plan for my local rheumy which was nerve tests on feet due to altered sensation, chase up over due dexa scan and to start tacrolimus. Bloods and urine were done with the results
Spanielmadlady
in
LUPUS UK
25 days ago
Supraclavicular Lymph Nodes
Good evening ladies. My wife was diagnosed with OC in 2020 She's currently undergoing chemotherapy Carboplatin and Gemcitabine for a reoccurrence that has progressed to her supraclavicular lymph nodes and at the porta hepatis . She's unfortunately experiencing swelling, increasing pain/discomfort
Good evening ladies. My wife was diagnosed with OC in 2020 She's currently undergoing chemotherapy Carboplatin and Gemcitabine for a reoccurrence that has progressed to her supraclavicular lymph nodes and at the porta hepatis . She's unfortunately experiencing swelling, increasing pain/discomfort
Cardiff05
in
My Ovacome
25 days ago
Skin Problems
I took 2 doses of Fasenra and now developed Eczema which I NEVER had. Does anyone else have this problem ? Thanks, Maria
I took 2 doses of Fasenra and now developed Eczema which I NEVER had. Does anyone else have this problem ? Thanks, Maria
cuyperu
in
Asthma Community Forum
26 days ago
Another Update!!
My tests went well today and no sign of cancer. The Cystoscopy wasn’t as scary or uncomfortable as I had thought and Yes PMR Pro better than the dreaded smear test. Its great news. Thank you all for your support and kindness. It meant a lot. Xx
My tests went well today and no sign of cancer. The Cystoscopy wasn’t as scary or uncomfortable as I had thought and Yes PMR Pro better than the dreaded smear test. Its great news. Thank you all for your support and kindness. It meant a lot. Xx
Macas
in
PMRGCAuk
26 days ago
nodule in lung
Hi, hope you are all having a good day. I have been told there is a large nodule in my right lung. I saw the thoracic surgeon a month ago and he said the PET scan did not "light up" so the nodule is not growing. I am to have another PET scan in December. I was a smoker but quit 15 years ago. Also,
Hi, hope you are all having a good day. I have been told there is a large nodule in my right lung. I saw the thoracic surgeon a month ago and he said the PET scan did not "light up" so the nodule is not growing. I am to have another PET scan in December. I was a smoker but quit 15 years ago. Also,
Daewood1949
in
Lung Conditions Community Forum
26 days ago
FDA Grants Fast Track Designation to HP518 for AR+ TNBC
The FDA has granted fast track designation to HP518 as a potential therapeutic option for patients with androgen receptor (AR)–positive triple-negative breast cancer (TNBC).1 HP518 is a potent AR PROTAC degrader designed to degrade wild-type AR and AR ligand-binding domain mutations such as L702H.
The FDA has granted fast track designation to HP518 as a potential therapeutic option for patients with androgen receptor (AR)–positive triple-negative breast cancer (TNBC).1 HP518 is a potent AR PROTAC degrader designed to degrade wild-type AR and AR ligand-binding domain mutations such as L702H.
God_Loves_Me
in
Advanced Prostate Cancer
26 days ago
New to Doxil… any one have heart issues?
Hi Ladies- maybe you can help? In just two days, I am due for my 3rd infusion of Doxil… which started out hard but last month was fine. The problem now is that my Apple Watch keeps alarming… well by that I mean it alarms and notifies me each time my heart rate dips below 40 beats per min for 10 solid
Hi Ladies- maybe you can help? In just two days, I am due for my 3rd infusion of Doxil… which started out hard but last month was fine. The problem now is that my Apple Watch keeps alarming… well by that I mean it alarms and notifies me each time my heart rate dips below 40 beats per min for 10 solid
Bettybuckets
in
SHARE Metastatic Breast Cancer
27 days ago
Striving to walk again, more progression, radiation and Trodelvy advice and prayers most welcome.
Hello all! It has been a long time since I posted as my path has been plodding - learning to walk again, discovering even more bone progression, being pulled off Xeloda as it wasn’t working, more radiation and now Trodelvy. The extensive bone mets are making physical therapy a challenge for sure and
Hello all! It has been a long time since I posted as my path has been plodding - learning to walk again, discovering even more bone progression, being pulled off Xeloda as it wasn’t working, more radiation and now Trodelvy. The extensive bone mets are making physical therapy a challenge for sure and
Saltandlight
in
SHARE Metastatic Breast Cancer
28 days ago
Requesting Help to Develop Bespoke BAT Protocol
Brief history. Diagnosed in July 2020 with oligometastatic PC with PSA 1,600… picked at 13,000+ after biopsy, Gleason 8. One previous bone femur lesion ( succesfuly treated by SBRT and 3 pelvic lymphodes (succesfuly treated by Lu-177). Discordance and previous existence of FDG+/PSMA- lesions. Volume
Brief history. Diagnosed in July 2020 with oligometastatic PC with PSA 1,600… picked at 13,000+ after biopsy, Gleason 8. One previous bone femur lesion ( succesfuly treated by SBRT and 3 pelvic lymphodes (succesfuly treated by Lu-177). Discordance and previous existence of FDG+/PSMA- lesions. Volume
CurrentSEO
in
Advanced Prostate Cancer
1 year ago
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