New knowledge about neuroendocrine prostate cancer

[Maxone73]

CDC7, I have always hated that guy since I watched Star Wars...or was it another guy?

"These results nominate CDC7 inhibition as a therapeutic strategy to constrain lineage plasticity, as well as to effectively treat NE tumors de novo or after transformation. As simurosertib clinical efficacy trials are ongoing, this concept could be readily translated for patients at risk of transformation."

nature.com/articles/s41392-...

[Azores1]

thank you

[HikerWife]

Thank you. My husband has the TP53 mutation (as well as PTEN), which puts him at higher risk/worse prognosis. Saving in the jumbo files!

[j-o-h-n]

It was the guy imitating another guy.

Good Luck, Good Health and Good Humor.

j-o-h-n