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Fisetin
Fisetin has been covered in other posts but there may be something new here. Fisetin is a polyphenol found in foods like strawberries. Fisetin shows promise as a senolytic, or compound that removes harmful senescent cells. Dr. Terry Burns is a neurosurgeon who sees promise for such compounds for neuroregeneration
Fisetin has been covered in other posts but there may be something new here. Fisetin is a polyphenol found in foods like strawberries. Fisetin shows promise as a senolytic, or compound that removes harmful senescent cells. Dr. Terry Burns is a neurosurgeon who sees promise for such compounds for neuroregeneration
Zardoz
in
Cure Parkinson's
3 years ago
Niacin and Butyrate: Nutraceuticals Targeting Dysbiosis and Intestinal Permeability in Parkinson’s Disease
Niacin PD patients are found to have significantly decreased niacin levels compared to age-matched healthy controls [52]. This has been attributed to both the disease itself and the medication used to attenuate motor symptoms [58]. Sinemet, the most commonly used PD medication, includes carbidopa, which
Niacin PD patients are found to have significantly decreased niacin levels compared to age-matched healthy controls [52]. This has been attributed to both the disease itself and the medication used to attenuate motor symptoms [58]. Sinemet, the most commonly used PD medication, includes carbidopa, which
Farooqji
in
Cure Parkinson's
3 years ago
Stem Cell Transplantation at Mass General
I have posted about this particular stem cell transplantation at least twice before. I understand that it was a "pay for play" situation. I understand that it is an "N of 1" situation. I understand that "placebo effect" could be a factor. I understand that much broader studies may be necessary. With
I have posted about this particular stem cell transplantation at least twice before. I understand that it was a "pay for play" situation. I understand that it is an "N of 1" situation. I understand that "placebo effect" could be a factor. I understand that much broader studies may be necessary. With
jimcaster
in
Cure Parkinson's
3 years ago
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ATREMO PLUS to raise dopamine ?
Has anybody tried atremo plus ? Reviews are good. Can't put the order through. Not sure why. They are on the phone but don't return calls to Australia. I'm keen to try this favs bean product. Thanks all.
Has anybody tried atremo plus ? Reviews are good. Can't put the order through. Not sure why. They are on the phone but don't return calls to Australia. I'm keen to try this favs bean product. Thanks all.
Vegegardner
in
Cure Parkinson's
3 years ago
Temgesic is working!
I have been on the neupro patch for a number of years with great results. However, I know it’s only time before augmentation kicks in. So after reading previous posts about Temgesic I discussed it with my GP. She agreed to prescribe it and I have been great for past 12 days. I’m glad to be off the Dopamine
I have been on the neupro patch for a number of years with great results. However, I know it’s only time before augmentation kicks in. So after reading previous posts about Temgesic I discussed it with my GP. She agreed to prescribe it and I have been great for past 12 days. I’m glad to be off the Dopamine
Poppip
in
Restless Legs Syndrome
3 years ago
Thankful for this forum
Hello Everyone. I found this forum about a week and a half ago. I did a google search on side effects for Gabapentin and thankfully stumbled across this in the search results. I haven't posted much but have looked through a few of the topics relevant to me and they've been very helpful. I've had RLS
Hello Everyone. I found this forum about a week and a half ago. I did a google search on side effects for Gabapentin and thankfully stumbled across this in the search results. I haven't posted much but have looked through a few of the topics relevant to me and they've been very helpful. I've had RLS
BigAdam
in
Restless Legs Syndrome
3 years ago
How do we satisfy our dopamine crave? Why do I need to fulfill that emotion?
What can we do to overcome that overwhelming sensation of thrill?
What can we do to overcome that overwhelming sensation of thrill?
Hidden
in
CHADD's Adult ADHD Support
3 years ago
Avoid levodopa phobia
I was reading Simon’s latest article about the PD drug development pipeline, which is a good read anyway - https://scienceofparkinsons.com/2020/12/02/drug-pipeline/ - and watched this video from Dr Kelly Mills of Johns Hopkins University about disease-modifying vs symptomatic therapy - https://youtu.be
I was reading Simon’s latest article about the PD drug development pipeline, which is a good read anyway - https://scienceofparkinsons.com/2020/12/02/drug-pipeline/ - and watched this video from Dr Kelly Mills of Johns Hopkins University about disease-modifying vs symptomatic therapy - https://youtu.be
Cagey84
in
Cure Parkinson's
3 years ago
Secondary RLS, Nexplanon, antidepressants, and iron?
hi, i have another long winded post! :) the questions are also repeated in the post! questions (so you don’t have to read this whole thing if you don’t want ;)): -if my RLS is secondary, would i benefit from using a dopamine agonist? and if i were to take an SSRI or something like buspar, would i be
hi, i have another long winded post! :) the questions are also repeated in the post! questions (so you don’t have to read this whole thing if you don’t want ;)): -if my RLS is secondary, would i benefit from using a dopamine agonist? and if i were to take an SSRI or something like buspar, would i be
mmjxc
in
Restless Legs Syndrome
3 years ago
"Alternative" treatments are not harmless when whey cost you quality of life
It's common to read on this forum that alternatives are harmless and have no side effects. But what about when a PWP eschews traditional treatment in favour of an alternative, and their quality of life suffers as a result? All we have is the immediate future. Today. Probably tomorrow. Maybe the day
It's common to read on this forum that alternatives are harmless and have no side effects. But what about when a PWP eschews traditional treatment in favour of an alternative, and their quality of life suffers as a result? All we have is the immediate future. Today. Probably tomorrow. Maybe the day
Hidden
in
Cure Parkinson's
3 years ago
Confession
Some of you have reached out to me and have asked after hubby so I thought I would start a new post. Thank you for asking and for your concern. It’s been about 5 months since I last checked in. To be honest I needed an escape from seeing how many newbies have had a need for this site, how many people
Some of you have reached out to me and have asked after hubby so I thought I would start a new post. Thank you for asking and for your concern. It’s been about 5 months since I last checked in. To be honest I needed an escape from seeing how many newbies have had a need for this site, how many people
SewBears
in
PSP Association
3 years ago
Adult ADHD late diagnosis and onset of peri/ menopause hell.( tips, experience or wisdom??)
So I’m 53 and joined this because I feel more insane than ever. I was diagnosed having ADHD when I was 45 or 46...( I have zero sence of time and linear anything at moment) Any way ,?pist diagnosis my doctor urged me try adderal in conjunction with other psychotropic medications. This was a colleague
So I’m 53 and joined this because I feel more insane than ever. I was diagnosed having ADHD when I was 45 or 46...( I have zero sence of time and linear anything at moment) Any way ,?pist diagnosis my doctor urged me try adderal in conjunction with other psychotropic medications. This was a colleague
JenInk
in
CHADD's Adult ADHD Support
3 years ago
Confused and down.
I find it really hard to put into words how I feel. I've never experienced such low mood before. My brain feels like fog. There's like a little circle in the middle of brain that can focus, and the rest is just a blurry surrounding. I used to gamble while I had mild depression , because I craved that
I find it really hard to put into words how I feel. I've never experienced such low mood before. My brain feels like fog. There's like a little circle in the middle of brain that can focus, and the rest is just a blurry surrounding. I used to gamble while I had mild depression , because I craved that
Dalegee
in
Anxiety and Depression Support
3 years ago
Failing test
I was seen by a neuropsychologist two days ago. for a mental examination. He warned me it would be a difficult test. He didn't mention it would take over 3 hours. At first I felt I was doing well but as the hours passed I sorta crumbled under the pressure. Maybe low blood sugar from skipping
I was seen by a neuropsychologist two days ago. for a mental examination. He warned me it would be a difficult test. He didn't mention it would take over 3 hours. At first I felt I was doing well but as the hours passed I sorta crumbled under the pressure. Maybe low blood sugar from skipping
kaypeeoh
in
Cure Parkinson's
3 years ago
Article from John-Hopkins regaurding the effects of opiates on RLS
No question, I just wanted to post some of an article regaurding the effects of opiates on RLS (the full text can be found on John Hopkins university website. Dr. Willis (as in Willis-Ekbomb disease / RLS) in his description of this disease in 1685 also reported on the benefits of opiates for treating
No question, I just wanted to post some of an article regaurding the effects of opiates on RLS (the full text can be found on John Hopkins university website. Dr. Willis (as in Willis-Ekbomb disease / RLS) in his description of this disease in 1685 also reported on the benefits of opiates for treating
Stdorn
in
Restless Legs Syndrome
3 years ago
What happened to the post, Change Your Brain: Neuroscientist Dr. Andrew Huberman ?
I watched the video then went outside to exercise. When I came back in a couple hours later I can't find it. Maybe because dopamine wasn't mentioned til 40 minutes into the post? It started with Dr H talking about his rough upbringing, yahda, yahda, yahda. Boring. Then he says dopamine release
I watched the video then went outside to exercise. When I came back in a couple hours later I can't find it. Maybe because dopamine wasn't mentioned til 40 minutes into the post? It started with Dr H talking about his rough upbringing, yahda, yahda, yahda. Boring. Then he says dopamine release
kaypeeoh
in
Cure Parkinson's
3 years ago
6 year old with ADHD and ODD-Child has difficulty receiving compliments
When my son hears positive reinforcement and compliments, his behavior is much worse after. It’s almost as if he wants to prove his defiance and he can’t handle the dopamine spike. It makes it difficult to get him to the point of receiving more positive than negative feedback, especially with other
When my son hears positive reinforcement and compliments, his behavior is much worse after. It’s almost as if he wants to prove his defiance and he can’t handle the dopamine spike. It makes it difficult to get him to the point of receiving more positive than negative feedback, especially with other
ilovepumpkinspice
in
CHADD's ADHD Parents Together
3 years ago
I'm new here
Have had RLS for approx 25 years with varying degrees of discomfort. Experienced rebound and possibly augmentation with sinemet, Took pramipexole for about ten years and switched to ropinirole three years ago when pramipexole was no longer effective. Am now definitely experiencing augmentation with
Have had RLS for approx 25 years with varying degrees of discomfort. Experienced rebound and possibly augmentation with sinemet, Took pramipexole for about ten years and switched to ropinirole three years ago when pramipexole was no longer effective. Am now definitely experiencing augmentation with
goonerguy
in
Restless Legs Syndrome
4 years ago
Has anyone suffered really bad fatigue after brain injury? Does anyone have any advice? X
Hi! I was wondering if anyone has suffered with really bad fatigue? If so what were some of the things that helped? My partner is in rehab (his injury happened at the end of July) at the moment but is so fatigued almost all the time that it is preventing rehab and even weaning him off of his tracheostomy
Hi! I was wondering if anyone has suffered with really bad fatigue? If so what were some of the things that helped? My partner is in rehab (his injury happened at the end of July) at the moment but is so fatigued almost all the time that it is preventing rehab and even weaning him off of his tracheostomy
Loveandcats
in
Headway
4 years ago
i’m very lost, any advice please
*originally posted to a subreddit* really long post, sorry :/ i went down a research rabbit hole. i tried to find what was triggering it this time. the first time it was an antipsychotic i was on, the second time it was because i was constantly high and i was unmedicated (anxiety & depression). this
*originally posted to a subreddit* really long post, sorry :/ i went down a research rabbit hole. i tried to find what was triggering it this time. the first time it was an antipsychotic i was on, the second time it was because i was constantly high and i was unmedicated (anxiety & depression). this
mmjxc
in
Restless Legs Syndrome
4 years ago
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