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Pain on one side of hip and leg
Hi all , My father who was diagnosed with metastatic Gleason 10 , mets to bones, PCa in Feb. 2024 and currently on ADT(Abiraterone + Lupron) had experienced leg and hip pain on left side suddenly day before yesterday (21st Aug . 2024). His last PSA was 2.96 in Jun 2024(initially diagnosed at 79.5 PSA
Hi all , My father who was diagnosed with metastatic Gleason 10 , mets to bones, PCa in Feb. 2024 and currently on ADT(Abiraterone + Lupron) had experienced leg and hip pain on left side suddenly day before yesterday (21st Aug . 2024). His last PSA was 2.96 in Jun 2024(initially diagnosed at 79.5 PSA
jeetu_g27
in
Advanced Prostate Cancer
25 days ago
Mass on pancreas (cancer) - mets from PC or pancreatic cancer…?
My Dad (77) was diagnosed in the spring with stage 4 prostate cancer, Gleason 10 with mets to spine. He has since started hormone therapy and had radiation to his prostate. Recent scan showed a mass on the pancreas which came as a big surprise as the radiation had shrunk the mets on his spine and his
My Dad (77) was diagnosed in the spring with stage 4 prostate cancer, Gleason 10 with mets to spine. He has since started hormone therapy and had radiation to his prostate. Recent scan showed a mass on the pancreas which came as a big surprise as the radiation had shrunk the mets on his spine and his
LDC2024
in
Advanced Prostate Cancer
25 days ago
What's next?
Surgery, pelvic and prostate bed radiation. 2 years zytiga/lupron. PSA <0.04 for 2 years. Radiation oncologist agrees with 2 MO no scans till PSA rises. 2 MO say no more treatment unless PSA rises.What is best next treatment if needed? Nervous not being proactive.Both MOs agreed only 2 years lupron.
Surgery, pelvic and prostate bed radiation. 2 years zytiga/lupron. PSA <0.04 for 2 years. Radiation oncologist agrees with 2 MO no scans till PSA rises. 2 MO say no more treatment unless PSA rises.What is best next treatment if needed? Nervous not being proactive.Both MOs agreed only 2 years lupron.
rfgh20
in
Advanced Prostate Cancer
26 days ago
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Delayed Response
My dad had 2 shots of Pluvicto and each time his PSA went up. His oncologist stopped treatment and said it wasn’t working . While waiting for other options and a mutation test (no mutation), his PSA has dropped 15 points. Could this be a delayed response? Anyone else have a delayed response?
My dad had 2 shots of Pluvicto and each time his PSA went up. His oncologist stopped treatment and said it wasn’t working . While waiting for other options and a mutation test (no mutation), his PSA has dropped 15 points. Could this be a delayed response? Anyone else have a delayed response?
Jshaw916
in
Advanced Prostate Cancer
27 days ago
PSA and Testosterone update
My PSA increased after 6 weeks to 0.04 but my T dropped to 8.87 not sure how to think of this. I had no expectation, so it is what it is. Plan is my MO will give me a PSMA scan if a I get to 2.0 PSA. These numbers are so small that I know that they are meaningless at this point but I would still
My PSA increased after 6 weeks to 0.04 but my T dropped to 8.87 not sure how to think of this. I had no expectation, so it is what it is. Plan is my MO will give me a PSMA scan if a I get to 2.0 PSA. These numbers are so small that I know that they are meaningless at this point but I would still
Scout4answers
in
Advanced Prostate Cancer
27 days ago
Keytruda for prostrate cancer.
Had my prostrate removed, psa went up, had radiation, psa went up, went on eleguard, psa kept going up, tried erleada, did nothing, psa kept going up, now at 25, also found a tumor on bladder outside wall. Oncologist wid a blood test and it showed that keytruda might work. After 1 infusion, psa went
Had my prostrate removed, psa went up, had radiation, psa went up, went on eleguard, psa kept going up, tried erleada, did nothing, psa kept going up, now at 25, also found a tumor on bladder outside wall. Oncologist wid a blood test and it showed that keytruda might work. After 1 infusion, psa went
Lightfoot550
in
Advanced Prostate Cancer
27 days ago
Looking for Encouragement
Hello everyone. Im updating my husband’s profile and hoping to find others that are in a similar situation. He is 62 years old and recently diagnosed with stage IV prostate cancer. His PSA was 885 and has too many Mets to count from his skull to groin area. The urologist started him and casadex and
Hello everyone. Im updating my husband’s profile and hoping to find others that are in a similar situation. He is 62 years old and recently diagnosed with stage IV prostate cancer. His PSA was 885 and has too many Mets to count from his skull to groin area. The urologist started him and casadex and
Iber
in
Advanced Prostate Cancer
27 days ago
Update
Diagnosed 2019 Gleason 9 PSA 13.3 Docataxal Radio therapy presently on ADT still training intensely and making gains just had a PSA bump from 0.03 to 0.316 they told me not to worry but you how we are I am having a good run fatigue and minor urinary issues as expected still at work and giving my all
Diagnosed 2019 Gleason 9 PSA 13.3 Docataxal Radio therapy presently on ADT still training intensely and making gains just had a PSA bump from 0.03 to 0.316 they told me not to worry but you how we are I am having a good run fatigue and minor urinary issues as expected still at work and giving my all
Bodysculpture
in
Advanced Prostate Cancer
28 days ago
How does Lynparza work?
I am brca2+ and 3 months into Lynparza. Stopped Zytiga, continuing ADT. I generally tolerate meds ok, but am finding this one v toxic. As I understand it, the brca2 gene mutation is in all cells, not just cancerous ones. In this case, Lynparza could be preventing parp from getting to healthy cells
I am brca2+ and 3 months into Lynparza. Stopped Zytiga, continuing ADT. I generally tolerate meds ok, but am finding this one v toxic. As I understand it, the brca2 gene mutation is in all cells, not just cancerous ones. In this case, Lynparza could be preventing parp from getting to healthy cells
Ian99
in
Advanced Prostate Cancer
28 days ago
The steroid with zytiga can be a deal
My Dads new oncologist switched his steroid from prednisolone to dexamethasone - she was distressed at first appointment to see he was on zytiga and prednisolone. She said research pretty clear that dexamethasone is better. On today's PSA results she is clearly correct. We thought that he had become
My Dads new oncologist switched his steroid from prednisolone to dexamethasone - she was distressed at first appointment to see he was on zytiga and prednisolone. She said research pretty clear that dexamethasone is better. On today's PSA results she is clearly correct. We thought that he had become
TomsD1
in
Advanced Prostate Cancer
28 days ago
What's so wrong with refusing all treatment?
I am 59 and have what is now (according to my doctor and PSA results) stage 2 prostate cancer, which my doctor insists can still be cured with surgery and is begging me to have, but since he told me I would forever lose any ability to have an erection, I have refused any and all treatment. I have been
I am 59 and have what is now (according to my doctor and PSA results) stage 2 prostate cancer, which my doctor insists can still be cured with surgery and is begging me to have, but since he told me I would forever lose any ability to have an erection, I have refused any and all treatment. I have been
crazysexyfun
in
Prostate Cancer And Gay Men
28 days ago
Does the acute kidney injury mislead the PSA number?
I am doing clinical trials - ARX517. I think i have its side effect that include protein in urine, pulse in urine and also creatine level is up clinical trials update here : https://healthunlocked.com/advanced-prostate-cancer/posts/150713089/nct04662580-all-about-arx517-as-monotherapy Question is
I am doing clinical trials - ARX517. I think i have its side effect that include protein in urine, pulse in urine and also creatine level is up clinical trials update here : https://healthunlocked.com/advanced-prostate-cancer/posts/150713089/nct04662580-all-about-arx517-as-monotherapy Question is
God_Loves_Me
in
Advanced Prostate Cancer
28 days ago
Decision Time
Hi All, I recently posted with my situation and have a follow-up (final I hope) with Dr. Gorovets at MSK to finalize my non-surgical treatment plan. Just looking for any input, thoughts, advice. Greatly appreciated as always. I'm 60, GS 4+3, PSA 5.5, Decipher .55, clean PSMA Pet (full details in
Hi All, I recently posted with my situation and have a follow-up (final I hope) with Dr. Gorovets at MSK to finalize my non-surgical treatment plan. Just looking for any input, thoughts, advice. Greatly appreciated as always. I'm 60, GS 4+3, PSA 5.5, Decipher .55, clean PSMA Pet (full details in
MrGreenJeans
in
Prostate Cancer Network
28 days ago
Abiraterone plus dexa, Lupron, Erleada
Question: Will adding Erleada , already taking these 2 drugs (not counting dexa) Abiraterone plus dexa and Quartely lupron injections increase overall survival? triplet, Right now treatment is Abi & Lupron. I'm high volume metastatic. Slowly rising PSA as of July 1.2. When PSA over 2 or fast doubling
Question: Will adding Erleada , already taking these 2 drugs (not counting dexa) Abiraterone plus dexa and Quartely lupron injections increase overall survival? triplet, Right now treatment is Abi & Lupron. I'm high volume metastatic. Slowly rising PSA as of July 1.2. When PSA over 2 or fast doubling
wolverine11
in
Advanced Prostate Cancer
28 days ago
looking for encouraging Pluvicto results
Hello fellow warriors, I know there have been posts of Pluvicto both helping and failing. I am now awaiting a PSMA PET scan to discuss possibly doing Pluvicto. I was diagnosed in 2018 at 46 years old with mets to about 5 spots in the bones. I have been on ADT since the beginning. I was on Zytiga then
Hello fellow warriors, I know there have been posts of Pluvicto both helping and failing. I am now awaiting a PSMA PET scan to discuss possibly doing Pluvicto. I was diagnosed in 2018 at 46 years old with mets to about 5 spots in the bones. I have been on ADT since the beginning. I was on Zytiga then
Oct18
in
Advanced Prostate Cancer
28 days ago
1/2 way through Xofigo with Apaludamide increasingly ineffective. PSA is declining. MO tells me Xofigo not the cause.
Hello all. 18 months since diagnosed stage 4 metastatic PC. Mets almost everywhere. PSA was 512 at diagnosis. Apaludamide/Trelstar combo lowered PSA to 0.60. Began to climb again April this year and Xofigo was suggested. I've now completed 3 of 6 treatments. Told Xofigo isn't to reduce PSA by my MO
Hello all. 18 months since diagnosed stage 4 metastatic PC. Mets almost everywhere. PSA was 512 at diagnosis. Apaludamide/Trelstar combo lowered PSA to 0.60. Began to climb again April this year and Xofigo was suggested. I've now completed 3 of 6 treatments. Told Xofigo isn't to reduce PSA by my MO
VisorF9
in
Advanced Prostate Cancer
28 days ago
What’s Next?
My bio illustrates my long 19 year journey with this disease. I turned out to be a great candidate for Pluvicto. All was going well. After cycle 3, a PSMA-PET showed all but one metastases were receding or dead. My PSA before cycle 4 was 17.7. My PSA before cycle 5 was 33.15. Due to the fast increase
My bio illustrates my long 19 year journey with this disease. I turned out to be a great candidate for Pluvicto. All was going well. After cycle 3, a PSMA-PET showed all but one metastases were receding or dead. My PSA before cycle 4 was 17.7. My PSA before cycle 5 was 33.15. Due to the fast increase
MJCA
in
Advanced Prostate Cancer
28 days ago
What’s Next?
My bio illustrates my long 19 year journey with this disease. I turned out to be a great candidate for Pluvicto. All was going well. After cycle 3, a PSMA-PET showed all but one metastases were receding or dead. My PSA before cycle 4 was 17.7. My PSA before cycle 5 was 33.15. Due to the fast increase
My bio illustrates my long 19 year journey with this disease. I turned out to be a great candidate for Pluvicto. All was going well. After cycle 3, a PSMA-PET showed all but one metastases were receding or dead. My PSA before cycle 4 was 17.7. My PSA before cycle 5 was 33.15. Due to the fast increase
MJCA
in
Prostate Cancer And Gay Men
28 days ago
3rd & 4th pBAT cycle results with daro question
Started 3rd pBAT cycle on 6-4-24 with a PSA of 0.58 measured 1 day earlier, 32 days after last of 6 T injections. Started 4th cycle on 7-26-24 with a PSA of 0.59 measured 2 days earlier, 34 days after last of 9 T injections. Tomorrow I will start my first loT phase with darolutamide (see below question
Started 3rd pBAT cycle on 6-4-24 with a PSA of 0.58 measured 1 day earlier, 32 days after last of 6 T injections. Started 4th cycle on 7-26-24 with a PSA of 0.59 measured 2 days earlier, 34 days after last of 9 T injections. Tomorrow I will start my first loT phase with darolutamide (see below question
Ichthus316
in
Fight Prostate Cancer
29 days ago
My first PSA after HT reporting confusion
I’ve just finish 19 months of Zoladex and RT to prostate only (localised G9 / PSMA/CT clear no evidence of SV involvement with PSA 6) My usual lab have been reporting my PSA as <0.01 ug/L since RT 18 months ago. My first 3 month testosterone is 0.8 nmol/L (23 ng/dL) and my PSA <0.03 ! Why is it
I’ve just finish 19 months of Zoladex and RT to prostate only (localised G9 / PSMA/CT clear no evidence of SV involvement with PSA 6) My usual lab have been reporting my PSA as <0.01 ug/L since RT 18 months ago. My first 3 month testosterone is 0.8 nmol/L (23 ng/dL) and my PSA <0.03 ! Why is it
SimMartin
in
Advanced Prostate Cancer
30 days ago
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