I know there have been posts of Pluvicto both helping and failing. I am now awaiting a PSMA PET scan to discuss possibly doing Pluvicto. I was diagnosed in 2018 at 46 years old with mets to about 5 spots in the bones. I have been on ADT since the beginning. I was on Zytiga then Xtandi for a total of 3 years. I aslo had radiation to those spots in my bones. My PSMA PET scan showed 6 spots in December of 2021 so my Dr at Duke zapped 3 spots and then I did Provenge in early 2022. My PSA dropped to 0.25 so we monitored the PSA until it had gotten over 2 then I did a clinical trial for about a year. Once the PSA rose to about 17 and a spot showed on my spine, I stopped the clinical trial and started Docetaxel Oct. 2023. I had a good reponse to that as well - did 10 rounds and the PSA got down to 1.4. My last treatment was May 2 of this year. Now my PSA has gone up over the last 3 months: 2.2, 2.1, 3.1, and 6.1 now.
Have many had any good, "long term" results from Pluvicto? In our world "long term" is obviously more like a year or longer....I think we all hold on to those "success" stories to provide some inspiration....just looking for some.
Thanks
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Oct18
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Hubby had a good response 18 months ago to Pluvicto-PSA drop of 90% and scans showing decrease in size of Mets. PSA began rising about 6 months after 6 treatments ended. He is now on the second cycle of infusions. We’re hoping for more success.
Where do you live ? To better understanding, 18 months ago. he had 6 rounds of pluvicto that works great..now doctor wants him to do another 4 rounds of pluvicto because had great success in fast.
Husband is 76 and we live in Virginia. His treatments are at UVA. He had the first 6 infusions every 6 weeks from December 23 to August 24. PSA went down to 10, but began climbing again in February. Because he had such success with the first cycle, doctors thought he was a good candidate to use it again.( 3 infusions planned initially this cycle). PSA rose to 190 before he started the second cycle in June. He is UVA’s first patient to have more than 6 infusions. PSA has not started back down yet.
hello, you can refer to my bio if you want more details. I did three rounds of Pluvicto in India late 2021. I started with my PSA at 3 and got it down to .66. Unfortunately a couple months after I finish the treatment my PSA began to rise again. I am now doing six rounds of Pluvicto. I actually just had my fourth treatment yesterday. My PSA was in the 50s when I started. It is now down to 17 after my last set of bloodwork. I am hoping that doing more rounds will give me a little bit more longevity, but we will see. Good luck to you.
Hi OCT my results thus far very positive. I have 2 more PSA tests to add to my bio but they have been the same as the previous ones essentially halving my PSA every 3 months. I didnt want to loose your post in the midst of being busy today so I am lazily just adding my recent post here for you.
Its ironic. Before Pluvitco was approved in the U>S> everyone was promoting it and if they had the means travelling overseas to get treatment. Now it seem there are more nay sayers complaining about not enough survival or time to progression results.
BTW I count the time I was on Pluvicto as survival not just the time I get after the treatment. During treatment I may have had additional fatigue here and there but very negligible. Only real SE was/is my saliva glands shut down.
I'm sure I am bias due to my good results but if Pluvicto is offered one should take it. Sure its a crap shoot with the 30%,30%,30% but man if you happen to be a responder it is a great treatment with for most very little in the way of SE's.
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