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Diamine oxidase
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Found something that is helping so far!
I was diagnosed at age 35 with ADHD by my therapist who recognized the life patterns I had. My therapist disclosed they also have ADHD and recognized the same struggles they had dealt with when they were younger. I had two kids pretty close together in 2021 and 2022 and due to covid started working from
I was diagnosed at age 35 with ADHD by my therapist who recognized the life patterns I had. My therapist disclosed they also have ADHD and recognized the same struggles they had dealt with when they were younger. I had two kids pretty close together in 2021 and 2022 and due to covid started working from
BlessedNeuroDiverse
in
CHADD's Adult ADHD Support
1 year ago
How to wean off of ropinirole and find a good doctor.
My husband is on 8 mg of ropinirole ER a day (4 in morning and 4 in evening. He has been taking it for over 15 years and whenever he would start getting augmentation, he would just increase the dose. That always worked but it’s way too much. We just moved to Florida and cannot find a good doctor for
My husband is on 8 mg of ropinirole ER a day (4 in morning and 4 in evening. He has been taking it for over 15 years and whenever he would start getting augmentation, he would just increase the dose. That always worked but it’s way too much. We just moved to Florida and cannot find a good doctor for
Sandalsforever
in
Restless Legs Syndrome
1 year ago
For a good time.... call Dopamine T-shirt
Another T-shirt design you might see in a men's bathroom. This is a molecule of Dopamine resembling a lady. Her face is a benzene ring, her eyebrows and mouth are double bonds, her earrings are hydroxy groups, and the pendant on her necklace is an amine group. The phone number is actually the Chemical
Another T-shirt design you might see in a men's bathroom. This is a molecule of Dopamine resembling a lady. Her face is a benzene ring, her eyebrows and mouth are double bonds, her earrings are hydroxy groups, and the pendant on her necklace is an amine group. The phone number is actually the Chemical
DeanGreen
in
Cure Parkinson's
1 year ago
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Seeking advice for changing from Temgesic to Gabapentin for treating my refractory RLS.
I have moved to a new area and need to change Doctor. I had a double appt last week and the new Doctor refused to prescribe Temgesic. I have been taking tbis medication successfully for 2 years now. I am having my medical records sent through to the new medical practice. I thought I should look into
I have moved to a new area and need to change Doctor. I had a double appt last week and the new Doctor refused to prescribe Temgesic. I have been taking tbis medication successfully for 2 years now. I am having my medical records sent through to the new medical practice. I thought I should look into
Jules1953
in
Restless Legs Syndrome
1 year ago
Onset/diagnosis after years
Good morning. I welcome you very warmly. This is my first post. I am not from UK, so my English is poor, sorry for any mistakes. In a nutshell: my aunt got sick in 2012. The diagnosis: Parkinson's. Treatment with levodopa had short-lived effects so doctors decided to use DBS therapy. DBS did not have
Good morning. I welcome you very warmly. This is my first post. I am not from UK, so my English is poor, sorry for any mistakes. In a nutshell: my aunt got sick in 2012. The diagnosis: Parkinson's. Treatment with levodopa had short-lived effects so doctors decided to use DBS therapy. DBS did not have
Paulaaaa
in
PSP Association
1 year ago
Dopamine a key factor in whether people find exercise easy or hard
https://www.diabetes.co.uk/news/2023/apr/dopamine-a-key-factor-in-whether-people-find-exercise-easy-or-hard.html
https://www.diabetes.co.uk/news/2023/apr/dopamine-a-key-factor-in-whether-people-find-exercise-easy-or-hard.html
Farooqji
in
Cure Parkinson's
1 year ago
Has anyone experienced benefits from coq10
According to the following article Comparing the youngest age people to the oldest, the number of striatal dopamine transporters was cut by 46%, or 6.6% per decade of life.3 The rate of loss of dopamine transporters is accelerated in Parkinson's patients, and this age-related factor may suggest why
According to the following article Comparing the youngest age people to the oldest, the number of striatal dopamine transporters was cut by 46%, or 6.6% per decade of life.3 The rate of loss of dopamine transporters is accelerated in Parkinson's patients, and this age-related factor may suggest why
Farooqji
in
Cure Parkinson's
1 year ago
Anyone tried Black Seed Oil?
Black Seed Oil (Nigella Sativa) has Thymoquinone and has many good properties. There are a lot of articles available that highlight the benefits of Black Seed Oil. Here is a sample https://acta.bibl.u-szeged.hu/62036/1/ysm_2019_107.pdf Thymoquinone prevents neurodegeneration against MPTP in vivo
Black Seed Oil (Nigella Sativa) has Thymoquinone and has many good properties. There are a lot of articles available that highlight the benefits of Black Seed Oil. Here is a sample https://acta.bibl.u-szeged.hu/62036/1/ysm_2019_107.pdf Thymoquinone prevents neurodegeneration against MPTP in vivo
John_morris71
in
Cure Parkinson's
1 year ago
if there is a vaccine for PD or PD can be prevented
there will be no motivation to find a cure (to grow back dopamine neurons), after we this batch all die, there will be no more PD in the world, is that possible?
there will be no motivation to find a cure (to grow back dopamine neurons), after we this batch all die, there will be no more PD in the world, is that possible?
limcheeese22
in
Cure Parkinson's
1 year ago
Safinamide
hello I was diagnosed with PD in Nov 2019 and in May 2020 my right hand tremor was getting hard to tolerate as its amplitude had increased and it moved to include my left leg and chin. In May 2020, somewhat anxiously, I started on 1 yellow pill (Sinemet plus) at 8am, 1pm, and 6pm. Within 4-8 weeks
hello I was diagnosed with PD in Nov 2019 and in May 2020 my right hand tremor was getting hard to tolerate as its amplitude had increased and it moved to include my left leg and chin. In May 2020, somewhat anxiously, I started on 1 yellow pill (Sinemet plus) at 8am, 1pm, and 6pm. Within 4-8 weeks
Tomkins
in
Cure Parkinson's
1 year ago
The role of istradefylline in the Parkinson's disease armamentarium
https://pubmed.ncbi.nlm.nih.gov/37029952 Expert opinion: Istradefylline is safe and well tolerated. Its efficacy was pronounced, when patients were on a lower chronic oral levodopa regimen. Levodopa causes a homocysteine elevation, which reflects an impaired methylation potential. As a result, an up
https://pubmed.ncbi.nlm.nih.gov/37029952 Expert opinion: Istradefylline is safe and well tolerated. Its efficacy was pronounced, when patients were on a lower chronic oral levodopa regimen. Levodopa causes a homocysteine elevation, which reflects an impaired methylation potential. As a result, an up
Hidden
in
Cure Parkinson's
1 year ago
Research Funding
I have recently become aware of the fund raising difficulties faced by certain researchers with an alternative angle on PD treatments. A case in point is Dr Jonathan Sackner-Bernstein, whose proposition that a Dopamine excess within Doperminergic neurons might be toxic and thus responsible for their
I have recently become aware of the fund raising difficulties faced by certain researchers with an alternative angle on PD treatments. A case in point is Dr Jonathan Sackner-Bernstein, whose proposition that a Dopamine excess within Doperminergic neurons might be toxic and thus responsible for their
Hidden
in
Cure Parkinson's
1 year ago
augmentation on neupro+Gabapentin. should I switch to a different dopamine agonist? All that’s helping is cannabis.
I’ve been on Neupro 1mg patches for 4+ years. I also currently take 800mg Gabapentin: 400mg twice a day. In the last month my RLS symptoms have appeared nightly beginning around 9:30pm. I’m able to fall asleep but then wake up in the middle of the night with RLS symptoms. The only thing that’s helped
I’ve been on Neupro 1mg patches for 4+ years. I also currently take 800mg Gabapentin: 400mg twice a day. In the last month my RLS symptoms have appeared nightly beginning around 9:30pm. I’m able to fall asleep but then wake up in the middle of the night with RLS symptoms. The only thing that’s helped
Discopage
in
Restless Legs Syndrome
1 year ago
Parkinson's linked to higher levels of pheomelanin in brain: Could it be a biomarker or treatment target?
In a recent study published in Progress in Neurobiology, researchers discover that the substantia nigra of individuals with Parkinson’s disease had a higher concentration of pheomelanin, as well as pheomelanin markers associated with L-3,4-dihydroxyphenylalanine (DOPA) and dopamine, than healthy controls
In a recent study published in Progress in Neurobiology, researchers discover that the substantia nigra of individuals with Parkinson’s disease had a higher concentration of pheomelanin, as well as pheomelanin markers associated with L-3,4-dihydroxyphenylalanine (DOPA) and dopamine, than healthy controls
Hidden
in
Cure Parkinson's
1 year ago
My letter to all powers-that-be, following my desperation for urgent need for improvements in education of medics an in management of RLS
Dear curriculum creators and top docs, As a medic with published research on Restless Legs Syndrome (RLS), I raise a number of concerns and some possible solutions , which have largely been endorsed by ******* Education Policy, GMC, who recommends that I contact you with these concerns to enable change
Dear curriculum creators and top docs, As a medic with published research on Restless Legs Syndrome (RLS), I raise a number of concerns and some possible solutions , which have largely been endorsed by ******* Education Policy, GMC, who recommends that I contact you with these concerns to enable change
Kakally
in
Restless Legs Syndrome
1 year ago
Alternating meds
I wonder if anyone else has experience with a RLS therapy method of alternating .375 mg Pramipexole and Methadone 20-30 mg every 10 days? I also use marijuana which helps maybe 40% for about an hour. My case is very severe with many previous pharmacologic failures including Alpha 2 Ligands, Buprenorphine
I wonder if anyone else has experience with a RLS therapy method of alternating .375 mg Pramipexole and Methadone 20-30 mg every 10 days? I also use marijuana which helps maybe 40% for about an hour. My case is very severe with many previous pharmacologic failures including Alpha 2 Ligands, Buprenorphine
WelbyB
in
Restless Legs Syndrome
1 year ago
Augmentation Concerns Being Overblown?
04/03/23 Edit : In hindsight, with apologies to those have already responded - though I think the body of the post communicates the concern better - I wish I would have titled this post “
Is the risk of developing DA augmentation overblown?
” Also, I’ve had some unexpected issues come up but will
04/03/23 Edit : In hindsight, with apologies to those have already responded - though I think the body of the post communicates the concern better - I wish I would have titled this post “
Is the risk of developing DA augmentation overblown?
” Also, I’ve had some unexpected issues come up but will
ircam2112
in
Restless Legs Syndrome
1 year ago
Current Status and Future Perspectives on Stem Cell-Based Therapies for Parkinson’s Disease
The loss of a specific cell type, midbrain dopamine neurons in the substantia nigra, is the main cause of motor dysfunction in PD. Numerous preclinical and clinical studies using fetal cell transplantation have provided proof of concept that cell replacement therapy may be a viable therapeutic approach
The loss of a specific cell type, midbrain dopamine neurons in the substantia nigra, is the main cause of motor dysfunction in PD. Numerous preclinical and clinical studies using fetal cell transplantation have provided proof of concept that cell replacement therapy may be a viable therapeutic approach
Baron1
in
Cure Parkinson's
1 year ago
‘World's 1st' fetal brain stem cell transplant effective in Parkinson's disease: study
CHA University Bundang Medical Center (CBMC) said on Monday that its researchers proved the safety and effectiveness of dopamine neural precursor cells derived from fetal mesenchymal stem cells transplanted into patients with Parkinson's disease "for the first time in the world." Cell replacement therapy
CHA University Bundang Medical Center (CBMC) said on Monday that its researchers proved the safety and effectiveness of dopamine neural precursor cells derived from fetal mesenchymal stem cells transplanted into patients with Parkinson's disease "for the first time in the world." Cell replacement therapy
Baron1
in
Cure Parkinson's
1 year ago
Using L-Tyrosine with Fluoxetine (Prozac)?
hello new member here. I’ve recently been prescribed Fluoxetine 20mg and was just wondering if it’s fine to take with 500mg L-Tyrosine thanks? After doing a bit of research it seems Fluoxetine increases serotonin levels in the brain but does absolutely nothing for Dopamine levels which is why I would
hello new member here. I’ve recently been prescribed Fluoxetine 20mg and was just wondering if it’s fine to take with 500mg L-Tyrosine thanks? After doing a bit of research it seems Fluoxetine increases serotonin levels in the brain but does absolutely nothing for Dopamine levels which is why I would
DP199777
in
Anxiety and Depression Support
1 year ago
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