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Why Dopamine Freezes Parkinson Patients And Drives Drug Addicts
A dopamine imbalance triggers Parkinson's disease and drug addition -- two opposite diseases. How it worked to do this in the brain had been a mystery. New research shows dopamine strengthens and weakens the two primary circuits in the brain that control our behavior. This provides new insight into why
A dopamine imbalance triggers Parkinson's disease and drug addition -- two opposite diseases. How it worked to do this in the brain had been a mystery. New research shows dopamine strengthens and weakens the two primary circuits in the brain that control our behavior. This provides new insight into why
Kia17
in
Cure Parkinson's
4 years ago
How is PD connected to Restless Leg Syndrome?
Or is it? I had a mild degree of RLS for several years. It wasn't enough of a problem to warrant medical help. Over the past few months the restless leg has gotten worse. Coincidentally two years I was diagnosed with PD. I was on Sinemet for over a year. Stopped it and switched to amantadine
Or is it? I had a mild degree of RLS for several years. It wasn't enough of a problem to warrant medical help. Over the past few months the restless leg has gotten worse. Coincidentally two years I was diagnosed with PD. I was on Sinemet for over a year. Stopped it and switched to amantadine
kaypeeoh
in
Cure Parkinson's
4 years ago
2 Compounds Show Ability to Protect Neurons, Raise Dopamine Levels
"Two compounds with hormone-like effects — prostaglandin E1 (PGE1) and prostaglandin A1 (PGA1) — may help to increase dopamine levels in the brain and slow Parkinson’s progression by activating a protein, called Nurr1, that supports dopaminergic neurons, a study reports." https://parkinsonsnewstoday.com
"Two compounds with hormone-like effects — prostaglandin E1 (PGE1) and prostaglandin A1 (PGA1) — may help to increase dopamine levels in the brain and slow Parkinson’s progression by activating a protein, called Nurr1, that supports dopaminergic neurons, a study reports." https://parkinsonsnewstoday.com
pvw2
in
Cure Parkinson's
4 years ago
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Is there a limit on Dopaboost intake?
My dad is on a surgery waitlist for DBS here in Canada (probably next year) and we could potentially do FUS in Switzerland... But in the meantime, we have been trying to figure out the best dopamine sources to help him on the daily. Mucuna is much more effective than his Sinemet, which barely works anymore
My dad is on a surgery waitlist for DBS here in Canada (probably next year) and we could potentially do FUS in Switzerland... But in the meantime, we have been trying to figure out the best dopamine sources to help him on the daily. Mucuna is much more effective than his Sinemet, which barely works anymore
pdkid
in
Cure Parkinson's
4 years ago
Life without dopamine
Is a lot less funner than with. Everything seems so boring. Nothing exciting. Trying to hang in there and take my b1. And 10 other meds and supplements. Hard to get excited when your brain has to squeeze itself so hard just to get a tiny drop of the reward neurotransmitter. Sorry just another rant
Is a lot less funner than with. Everything seems so boring. Nothing exciting. Trying to hang in there and take my b1. And 10 other meds and supplements. Hard to get excited when your brain has to squeeze itself so hard just to get a tiny drop of the reward neurotransmitter. Sorry just another rant
bassofspades
in
Cure Parkinson's
4 years ago
Other reasons for arm tremor?
If Sinemet or other dopamine agonists have no effect on tremor does that suggest the root problem is not a dopamine deficiency?
If Sinemet or other dopamine agonists have no effect on tremor does that suggest the root problem is not a dopamine deficiency?
kaypeeoh
in
Cure Parkinson's
4 years ago
Breathing abnormalities in Parkinsons
Several different patterns of breathing abnormality may be found in PD: Upper airway obstruction (UAO) has been reported in a third of people with PD. The most common manifestation of UAO is soft speech, which itself may affect up to 70% of people with PD. Two types of UAO have been described: (i)
Several different patterns of breathing abnormality may be found in PD: Upper airway obstruction (UAO) has been reported in a third of people with PD. The most common manifestation of UAO is soft speech, which itself may affect up to 70% of people with PD. Two types of UAO have been described: (i)
Hidden
in
Cure Parkinson's
4 years ago
Summary of Legitimate Stem Cell Therapy.
I recently received an email from Summit for Stem Cell Foundation which contained a great summary of legitimate stem cell research to combat Parkinson's Disease throughout the world. Here it is: Roger Barker, United Kingdom. (2018 – ongoing.) Fetal tissue transplants for Parkinson’s disease.
I recently received an email from Summit for Stem Cell Foundation which contained a great summary of legitimate stem cell research to combat Parkinson's Disease throughout the world. Here it is: Roger Barker, United Kingdom. (2018 – ongoing.) Fetal tissue transplants for Parkinson’s disease.
jimcaster
in
Cure Parkinson's
4 years ago
PD treatment using one’s own skin cells to produce More dopamine in the brain.
https://www.statnews.com/2020/05/12/medical-first-parkinsons-brain-cell-transplant-stem-cells The results will be published Wednesday in a medicinal journal. Doesn’t look to promising.
https://www.statnews.com/2020/05/12/medical-first-parkinsons-brain-cell-transplant-stem-cells The results will be published Wednesday in a medicinal journal. Doesn’t look to promising.
Cons10s
in
Cure Parkinson's
4 years ago
What are the downsides of NOT taking dopamine drugs?
Wondering if I should keep holding off on taking dopamine therapy. I've been avoiding taking it since my diagnosis a year ago due to an overall dislike of pharmaceuticals in general and in hopes of avoiding the side effects. Just watched a talk by Dr. Laurie Mischley (link below, at minute 26) where
Wondering if I should keep holding off on taking dopamine therapy. I've been avoiding taking it since my diagnosis a year ago due to an overall dislike of pharmaceuticals in general and in hopes of avoiding the side effects. Just watched a talk by Dr. Laurie Mischley (link below, at minute 26) where
lbrussell
in
Cure Parkinson's
4 years ago
Too much of a good thing
The publication twenty years ago describing excessive therapeutic drug dosing in some Parkinson's disease patients foreshadowed behaviours now well recognised. The recognition and description of a behavioural syndrome in a group of patients with Parkinson’s disease (PD) who take dopamine replacement
The publication twenty years ago describing excessive therapeutic drug dosing in some Parkinson's disease patients foreshadowed behaviours now well recognised. The recognition and description of a behavioural syndrome in a group of patients with Parkinson’s disease (PD) who take dopamine replacement
Farooqji
in
Cure Parkinson's
4 years ago
Stem Cell Success in Massachusetts
This was not a double blind test, so placebo effect cannot be ruled out, BUT two years after therapy, there's considerable reason for cautious optimism. "Two years after the surgeries, the patient has had no adverse events and reports improvements in daily function. Standardized examinations of motor
This was not a double blind test, so placebo effect cannot be ruled out, BUT two years after therapy, there's considerable reason for cautious optimism. "Two years after the surgeries, the patient has had no adverse events and reports improvements in daily function. Standardized examinations of motor
jimcaster
in
Cure Parkinson's
4 years ago
Excess sugars profoundly impacts your kidney health
Your nutrition influences metabolic waste output. What is best limited to enhance kidney health? Let’s talk sugars/fast carbs 1st: boiled/gummy sweets; concentrated fruit juice; ultra processed foods e.g shop cakes/pastries/some breads; fizzy pop; commercial ice-cream/lollies. And you know its not just
Your nutrition influences metabolic waste output. What is best limited to enhance kidney health? Let’s talk sugars/fast carbs 1st: boiled/gummy sweets; concentrated fruit juice; ultra processed foods e.g shop cakes/pastries/some breads; fizzy pop; commercial ice-cream/lollies. And you know its not just
WhollyAligned
Administrator
in
Nutrition and Yoga for Health
4 years ago
Might PD pharmaceuticals restore my athletic performance?
Hello. This week marks 1 year since my official PD diagnosis, although I had symptoms for a few years prior. I knew what was coming as my mother has battled PD for over 20 years. One thing that has bothered me is my slower speeds at both bicycling and walking. I have been a bicyclist for over 30 years
Hello. This week marks 1 year since my official PD diagnosis, although I had symptoms for a few years prior. I knew what was coming as my mother has battled PD for over 20 years. One thing that has bothered me is my slower speeds at both bicycling and walking. I have been a bicyclist for over 30 years
lbrussell
in
Cure Parkinson's
4 years ago
Depakote
Is anyone on here who has been or currently on depakote and has trouble sleeping? I've been tossing and turning at night. Is it known to cause sleeping problems?
Is anyone on here who has been or currently on depakote and has trouble sleeping? I've been tossing and turning at night. Is it known to cause sleeping problems?
MrsMapdog
in
My OCD Community
4 years ago
Parkinson’s: Autoimmune attack may start years before diagnosis
A new study adds an evidence reinforces the Auto- Immune attack to nerve cells which then develops PD . " Years before motor symptoms arise, other symptoms of Parkinson’s can appear, including a reduced sense of smell, constipation, mood changes, and REM sleep behavior disorder, which involves physically
A new study adds an evidence reinforces the Auto- Immune attack to nerve cells which then develops PD . " Years before motor symptoms arise, other symptoms of Parkinson’s can appear, including a reduced sense of smell, constipation, mood changes, and REM sleep behavior disorder, which involves physically
Abdiqani
in
Cure Parkinson's
4 years ago
Exercise
Hello, i got a question about exercise. I am a sprinter and always enjoyed it. I know the main trial for slowing brain disease was 30 min high intense max HR, on a treadmill. How do they know hitt workouts are not the same or better at protecting the brain. Have the done more trials on exercising?
Hello, i got a question about exercise. I am a sprinter and always enjoyed it. I know the main trial for slowing brain disease was 30 min high intense max HR, on a treadmill. How do they know hitt workouts are not the same or better at protecting the brain. Have the done more trials on exercising?
Girth10
in
Cure Parkinson's
4 years ago
Xarasho
I am Suffering from severe RLS and I’ve tried everything from vitamins to CBT OIL, 5 HTP Hydroxytry.. , nothing works, the only thing helps is the agnostic dopamine drugs which is for Parkinson disease, it has really bad side effects , please someone help me and be. genuine!!!
I am Suffering from severe RLS and I’ve tried everything from vitamins to CBT OIL, 5 HTP Hydroxytry.. , nothing works, the only thing helps is the agnostic dopamine drugs which is for Parkinson disease, it has really bad side effects , please someone help me and be. genuine!!!
Xarasho
in
Restless Legs Syndrome
4 years ago
Insomnia - Ropinorole & Pramipexole the same?
Hi, I have RLS which is under control with Ropinorole, however I think it's also causing me insomnia which I've been prescribed Gabapentin, which seems to help. I wanted to know though if Pramipexole (which I was using years ago) also causes insomnia? I know they are both dopamine antagonists but maybe
Hi, I have RLS which is under control with Ropinorole, however I think it's also causing me insomnia which I've been prescribed Gabapentin, which seems to help. I wanted to know though if Pramipexole (which I was using years ago) also causes insomnia? I know they are both dopamine antagonists but maybe
silkusmaximus
in
Restless Legs Syndrome
4 years ago
Dopamine,
Look for foods to increase dopamine !
Look for foods to increase dopamine !
gerrerd
in
Anxiety and Depression Support
4 years ago
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