Experiences with

Depakine

N-acetylcysteine Clinical Applications Oct 2024 - https://www.cureus.com/articles/311141-n-acetylcysteine-clinical-applications#!/ "Neurological Disorders NAC appears to be protective against neurodegenerative illnesses such as Parkinson's disease, Alzheimer's disease, stroke, and multiple

Hello I have only posted briefly before but read most of the posts. I am really in complete despair with regard to my 75 year old husband and the worsening of his RLS symptoms which are now intolerable. The situation is that he has had worsening RLS for about 5 years. Initially he found relief

Anyone seen this? This is what JSBMD is talking about https://pmc.ncbi.nlm.nih.gov/articles/PMC11083272/#sec6-ijms-25-04643 Conclusions TH inhibitors down-regulate DA levels and protect DA neurons, while DA receptor agonists function to activate post-synaptic DA receptors to alleviate PD symptoms

http://haidut.me/?p=219

My son-in-law has developed Parkinson's disease. I would like to suggest a brain health supplement that includes alpha-gpc, as well as several other nutrients. I am concerned the alpha-gpc might be counterproductive to dopamine levels. Can you advise?

I have read several times here that DAs should eventually lead to augmentation in all cases. Is there a scientific reference that supports this statement? I have looked into the litterature, and found augmentation rate as low as a few percents and up to 70%, which is quite confusing.

Parkinson’s disease (PD) is characterized by the loss of nerve cells responsible for producing dopamine, which causes movement difficulties and other symptoms. An important aspect of PD is the accumulation of a protein called α-synuclein in the brain, which triggers inflammation and worsens cell degeneration

I’ve found a way to use Levodopa, and it finally works for me—previously, I had very negative effects. In short, I take it not before going to bed but after I start experiencing RLS symptoms. At that point, dopamine levels are low in the brain, which prevents the neurotoxicity that causes the side effects

https://neurolrespract.biomedcentral.com/articles/10.1186/s42466-024-00353-0 The German RLS group has released new Guidelines for the Treatment of RLS.I haven't read them in detail yet. A quick skim read shows that they have dismissed the old 'Primary & secondary' RLS classification, which I agree

After waiting over two years since being referred, I have an appointment with a neurologist. With the help of pregabalin and opioids, I took my last dopamine agonist last July after being on them for 22 years. My life has changed; I can read a book, watch TV and sleep! Reasons to keep the appointment

I want to hear if you have used or using this dopamine supplement. Which one do you take? powder or L-dopa capsule? How it's effect your brain?

My original question todsy was was "can meditation or exercise help with grounding, settling emotional bad stuff? If yes, then how?I have some personal thoughts. And lots of experiences to debrief. This led to dopamineas as a topic. Six or ten or 18 websites later, this cropped up. Quite an interesting

I've had RLS since I was 40, 28 years ago. I've been on every medication known to mankind (and a few weird ones also) and been to 18 Healthcare professionals. I have been on so many dopamine agonists... for 20 years. I developed augmentation right away,, although no one realized what was happening

In many cases, the cause of RLS remains unknown. I conducted a long study and found the cause of RLS in my case. It's unlikely that my case is unique—though it's hard for me to judge how common it is, as one case can hardly be considered representative :). So, I’m sharing my findings here, hoping they

I have my daily struggles with my Parkinson’s symptoms and the on and off periods and the precise dosing of my sinemet during the daytime hours to get me through the day but once nighttime comes around my symptoms all but disappear. I’ve had Parkinson’s for close to 25 years and I’ve have never taken

Diagnosed in 2022, late onset at age 75 with slight symptoms before. Slightly dragging my left foot and unable to run was alarming and led me to get checked out. A recommended DATSCAN REVEALED a Dopamine shortage but not severe. Very slight additional symptoms. Doc recommended a very low dose initially

***Please read Jays comment below about interactions.** https://www.scoop.co.nz/stories/SC2410/S00048/world-first-discovery-shows-new-molecule-in-new-zealand-blackcurrants-inhibits-an-enzyme-that-degrades-dopamine.htm

I’m going to start the tortuous journey of coming off the awful Neupro patches. After 23 years of taking dopamine agonists I am dreading it. I think I want to switch back to pramipexole and then start decreasing the doses very slowly. I am on 3mg Neupro patches. Can I switch over immediately to taking

3 days of complete remission of PSP symptoms Hi, everybody! I’m still trying to find out how and why this happened to me. If someone of you went through a similar situation, please share the experience. Hereby a copy of my last chat with GPT for your information. Kind regards. ChatGPT 2024-10

I started taking TMG 1 cap and NAC 1 cap day before yesterday night. I have been feeling more off episodes for the last two days. Does TMG increase the production of dopamine resulting in an increased need for ldopa? Also any suggestions on the time to take the combo? I am generally under-medicated by