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What is role of hormonal therapy drug when taken with targeted therapy, eg Piqray or Ibrance?
I’ve been curious about this and wondering if anyone can explain. I want to better understand the role of the hormone therapy eg Faslodex when taken with targeted therapy such as Ibrance. Does it just reduce the amount of estrogen available to the cell and “lightens the load” on the targeted therapy?
I’ve been curious about this and wondering if anyone can explain. I want to better understand the role of the hormone therapy eg Faslodex when taken with targeted therapy such as Ibrance. Does it just reduce the amount of estrogen available to the cell and “lightens the load” on the targeted therapy?
HelenWi
in
SHARE Metastatic Breast Cancer
8 months ago
ADT SE’s
I had a 6 month Lupron shot in April last year. I experienced all the typical SE the worst being the hot flashes at night. I am following the Ssport protocol for a biological reoccurrence. Basically a 6 month adt with 39 radiation treatments last year. Current labs show undetectable PSA with a slow
I had a 6 month Lupron shot in April last year. I experienced all the typical SE the worst being the hot flashes at night. I am following the Ssport protocol for a biological reoccurrence. Basically a 6 month adt with 39 radiation treatments last year. Current labs show undetectable PSA with a slow
plato123
in
Advanced Prostate Cancer
4 months ago
doc report
My report came back metastatic breast to bone. I will have abot 2 weeks of radiation in the arm with hardware. I will take hormone therapy Letrozole and monthly injection Xgeva-no IV and no chemo. Watch thyroid nodules yearly. Doc V. is very aware of kidney function. Only colonoscopy tomorrow. Thanks
My report came back metastatic breast to bone. I will have abot 2 weeks of radiation in the arm with hardware. I will take hormone therapy Letrozole and monthly injection Xgeva-no IV and no chemo. Watch thyroid nodules yearly. Doc V. is very aware of kidney function. Only colonoscopy tomorrow. Thanks
nonna70
in
Kidney Disease
4 months ago
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Possible improvement of speech in Parkinsons patients with the encouragement and implementation of a daily walking routine.
The following postulation is a hope that our speech can be improved by implementing a consistent routine of daily walking. I discovered this amazingly beautiful yet simple concept by accident 🤔😁, after watching my 18 month old nephew have dramatic improvements in speech after graduating to walking
The following postulation is a hope that our speech can be improved by implementing a consistent routine of daily walking. I discovered this amazingly beautiful yet simple concept by accident 🤔😁, after watching my 18 month old nephew have dramatic improvements in speech after graduating to walking
pdpatient
in
Cure Parkinson's
9 months ago
Supplements
Hi lovelies, I have been wanting to start some supplements for my endo but not sure where to start? Currently my worse symptoms are my back and hip pain and my hormones ! I am on an induce chemical menopause and HRT. I’ve heard about NAC, would anyone recommend this to start on first? Thank
Hi lovelies, I have been wanting to start some supplements for my endo but not sure where to start? Currently my worse symptoms are my back and hip pain and my hormones ! I am on an induce chemical menopause and HRT. I’ve heard about NAC, would anyone recommend this to start on first? Thank
miajayne
in
Endometriosis UK
4 months ago
One month of Orgovyx completed
Just a quick update for those Brothers on, or considering ADT with, Orgovyx. Today I started the second month of my 6 month sentence. As of today I have had virtually no side effects. I purposely lost 8 pounds prior to going on it, and today the scale says I am down another pound. Just back
Just a quick update for those Brothers on, or considering ADT with, Orgovyx. Today I started the second month of my 6 month sentence. As of today I have had virtually no side effects. I purposely lost 8 pounds prior to going on it, and today the scale says I am down another pound. Just back
ToolBeltZia
in
Prostate Cancer Network
4 months ago
Perimenopause and Venlafaxine?
Hi all I'm 45 years old and have been on HRT (Estradiol + Utrogestan) for a year now. My main symptoms used to be mood swings, night sweats, difficulty to sleep through and hot flushes, which are mostly gone since I've been taking the tablet + applying the gel. The only side effect is that I've put
Hi all I'm 45 years old and have been on HRT (Estradiol + Utrogestan) for a year now. My main symptoms used to be mood swings, night sweats, difficulty to sleep through and hot flushes, which are mostly gone since I've been taking the tablet + applying the gel. The only side effect is that I've put
myku92
in
Menopause and Perimenopause Support
4 months ago
PSMA PET Scan????
I'm 4-3/4 years on ADT, MO has ordered NO Scans for 2 years even though I've complained of returning bone pain , groin pain, pain in ribs and spine, as well as thigh and pelvic pain. Also pre treatment cough has returned, (was diagnosed with lung mets as well as bone and lymph node).No scans have been
I'm 4-3/4 years on ADT, MO has ordered NO Scans for 2 years even though I've complained of returning bone pain , groin pain, pain in ribs and spine, as well as thigh and pelvic pain. Also pre treatment cough has returned, (was diagnosed with lung mets as well as bone and lymph node).No scans have been
TommyCarz2
in
Advanced Prostate Cancer
4 months ago
HRT Questions
I wondered if any members could recommend or suggest good bioidentical HRT products. I've been on HRT for nearly 7 years. I went into menopause very abruptly after I came off the pill. A lot of weird health issues reared their head at the same time and I admit I wasn't very well at the time. I've mentioned
I wondered if any members could recommend or suggest good bioidentical HRT products. I've been on HRT for nearly 7 years. I went into menopause very abruptly after I came off the pill. A lot of weird health issues reared their head at the same time and I admit I wasn't very well at the time. I've mentioned
Sparklingsunshine
in
Thyroid UK
4 months ago
Painful Breast
I posted this some years ago on behalf on my wife: She has had a pain in the upper inner right quadrant of the breast for the last 2 years. When this first came up she had an appointment at our local hospital and received a bilateral mammogram and all was normal. There was no focal lesion seen. The
I posted this some years ago on behalf on my wife: She has had a pain in the upper inner right quadrant of the breast for the last 2 years. When this first came up she had an appointment at our local hospital and received a bilateral mammogram and all was normal. There was no focal lesion seen. The
RobertCLL
in
My Breast Cancer Community
4 months ago
HRT or not?
I’m currently taking 75mg of levo & a lot of other vitamins, but still feel tired in the afternoons. I usually need a 2 hour nap, but it’s difficult as I work full time. I should think many of you feel the same. I saw the endo at hospital who said my levels were fine & sent me away. I’m waiting
I’m currently taking 75mg of levo & a lot of other vitamins, but still feel tired in the afternoons. I usually need a 2 hour nap, but it’s difficult as I work full time. I should think many of you feel the same. I saw the endo at hospital who said my levels were fine & sent me away. I’m waiting
Beautifulmagnolia
in
Thyroid UK
4 months ago
HRT Question
Hello Ladies I hope you all had a wonderful Christmas and wishing you all a joyous, prosperous and blessed 2024, in good health and happiness! I wanted to ask a bit of a silly question I guess, but how do I know 1. If I’m on the right kind of HRT 2. How much HRT I need 3. When I’m taking enough
Hello Ladies I hope you all had a wonderful Christmas and wishing you all a joyous, prosperous and blessed 2024, in good health and happiness! I wanted to ask a bit of a silly question I guess, but how do I know 1. If I’m on the right kind of HRT 2. How much HRT I need 3. When I’m taking enough
Amazon07
in
Thyroid UK
4 months ago
Bright Light Therapy Zoom Call Sat Aug 5 Noon Eastern
30 minute meeting to talk about Bright Light Therapy for PD Sat 5 Aug at Noon Eastern. https://us05web.zoom.us/j/82099215722?pwd=novCzckkWh2jyFYw8uuFXHR2TDJt8P.1 I am not an expert on Bright Light Therapy but it looks useful and I have been trying it for a while. Surprisingly, it may be best to do
30 minute meeting to talk about Bright Light Therapy for PD Sat 5 Aug at Noon Eastern. https://us05web.zoom.us/j/82099215722?pwd=novCzckkWh2jyFYw8uuFXHR2TDJt8P.1 I am not an expert on Bright Light Therapy but it looks useful and I have been trying it for a while. Surprisingly, it may be best to do
Bolt_Upright
in
Cure Parkinson's
10 months ago
Bereavement in depression
I lost my job 6 month’s ago, this was because I messed up while having to stop my HRT, I had to stop cold turkey and it made me loopy, depression and anxiety took over, struggling to get out of bed, but feeling guilty not having a job, trying to get one, but not at the top of my game and not being successful
I lost my job 6 month’s ago, this was because I messed up while having to stop my HRT, I had to stop cold turkey and it made me loopy, depression and anxiety took over, struggling to get out of bed, but feeling guilty not having a job, trying to get one, but not at the top of my game and not being successful
Desperatetoloose
in
My EXI Community
4 months ago
Anger
Good morning, I had seen here recently some comments on anger and how ADT increases it. This is the first I've read about this, and it makes sense as I look back, I have developed anger issues. Question, is it anger from just being in this messed up situation, ADT for a decade, and just feeling the
Good morning, I had seen here recently some comments on anger and how ADT increases it. This is the first I've read about this, and it makes sense as I look back, I have developed anger issues. Question, is it anger from just being in this messed up situation, ADT for a decade, and just feeling the
Survivor1965
in
Advanced Prostate Cancer
4 months ago
Into the Great Unknown
Well, I just wrapped up two years of ADT (Lupron and Xtandi) on top of 36 rounds of radiation, and a RARP. At 57 when diagnosed (PSA 5.2, Gleason 4+3, one affected pelvic lymph node per PSMA PET scan), our plan was to throw the kitchen sink at my PCa and see if we can’t knock it out. Here I am at 59
Well, I just wrapped up two years of ADT (Lupron and Xtandi) on top of 36 rounds of radiation, and a RARP. At 57 when diagnosed (PSA 5.2, Gleason 4+3, one affected pelvic lymph node per PSMA PET scan), our plan was to throw the kitchen sink at my PCa and see if we can’t knock it out. Here I am at 59
aloha_spaceman
in
Advanced Prostate Cancer
5 months ago
Drugs interactions
I am on Lupron as the only current PC treatment. Testosterone is <>1% as of Dec/18. PCP is looking to get me on (very expensive , hard to get) Serostim to help me with HIV/PC wasting SE's Thoughts, please be kind as ADT makes me get upset for nothing. Thank you.
I am on Lupron as the only current PC treatment. Testosterone is <>1% as of Dec/18. PCP is looking to get me on (very expensive , hard to get) Serostim to help me with HIV/PC wasting SE's Thoughts, please be kind as ADT makes me get upset for nothing. Thank you.
Blueribbon63
in
Advanced Prostate Cancer
5 months ago
Newly diagnosed researching lifestyle changes
Hi there, Had a overall physical of everything which included PSA which was 6 in 2016 and didn't put any attention to it and ignored it, nobody I spoke with who saw the report said to do anything. No family history of prostate cancer that I know of. Now 7 years later age 64, PSA 18, Free PSA 11%
Hi there, Had a overall physical of everything which included PSA which was 6 in 2016 and didn't put any attention to it and ignored it, nobody I spoke with who saw the report said to do anything. No family history of prostate cancer that I know of. Now 7 years later age 64, PSA 18, Free PSA 11%
Nwdx
in
Advanced Prostate Cancer
3 months ago
help - started oestrogel- 4th day - but does it lower thyroid ? My stomach motility stopped again
hi wonderful people I started HRT oestrogel and 4th day and 2 pumps - I have really bad bloating and zero stomach motility - Does it interfere with thyroid t4 or t3 ? I have read it can lower thyroid or block the cell ? When stomaxh motility is so bad I can’t eat properly and weight is low but can
hi wonderful people I started HRT oestrogel and 4th day and 2 pumps - I have really bad bloating and zero stomach motility - Does it interfere with thyroid t4 or t3 ? I have read it can lower thyroid or block the cell ? When stomaxh motility is so bad I can’t eat properly and weight is low but can
Chouchou1234
in
Thyroid UK
5 months ago
PSA after radiation and Hormone therapy prognosis
https://meetings.asco.org/abstracts-presentations/218387 I have be searching for some data on the impact of radiation and short term hormone therapy on Intermediate cancer. If anyone else has some additional data or experiences please post Background. I finishing up 25 doses of radiation to the
https://meetings.asco.org/abstracts-presentations/218387 I have be searching for some data on the impact of radiation and short term hormone therapy on Intermediate cancer. If anyone else has some additional data or experiences please post Background. I finishing up 25 doses of radiation to the
Mgtd
in
Prostate Cancer Network
5 months ago
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