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ADT or not?
Hi, i have Stage 4 PCA, Gleason 5+4 so I am on Degaralix and Enzalutamide. I tend to refer to this treatment as ADT as shorthand because to my mind they both reduce testosterone. I wonder if I’m misusing ADT or does it matter?
Hi, i have Stage 4 PCA, Gleason 5+4 so I am on Degaralix and Enzalutamide. I tend to refer to this treatment as ADT as shorthand because to my mind they both reduce testosterone. I wonder if I’m misusing ADT or does it matter?
FortyWinks
in
Advanced Prostate Cancer
8 months ago
UserName Change Search Link
I just changed my username name from the impersonal "JHMX" to "JohnInTheMiddle". Among other things I liked the TV show Malcolm in the Middle. And when I signed up it was in that kind of crazy time of DX that many people here will recognize. But as I become familiar with the stories and exploration here
I just changed my username name from the impersonal "JHMX" to "JohnInTheMiddle". Among other things I liked the TV show Malcolm in the Middle. And when I signed up it was in that kind of crazy time of DX that many people here will recognize. But as I become familiar with the stories and exploration here
JohnInTheMiddle
in
Advanced Prostate Cancer
8 months ago
ADT duration data measures
odd query but when reading studies and research on ADT duration they refer to months or years - I am curious as the implants are often prescribed monthly or 3 monthly but that actually means 4 weekly or 12 weekly with such ADT as goserelin - so are the studies that say 4, 6, 18, 24, 36 months referring
odd query but when reading studies and research on ADT duration they refer to months or years - I am curious as the implants are often prescribed monthly or 3 monthly but that actually means 4 weekly or 12 weekly with such ADT as goserelin - so are the studies that say 4, 6, 18, 24, 36 months referring
SimMartin
in
Advanced Prostate Cancer
8 months ago
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Anxiety (GAD) : MY UNDERSTANDING, MY EXPERIENCE N MY PERSPECTIVE…..🧠🧠 PART
.🙏🙏….. pratyaya singh #anxiety #generalized anxiety disorder #GAD #perspectives #
CBT
#
Cognitive
behavioural
therapy
#myths around anxiety #mindset #hope #faith #empathy #support #medical help #mental health issues #positive mind set #personal experience #face it fight with it #positivity #motivation
.🙏🙏….. pratyaya singh #anxiety #generalized anxiety disorder #GAD #perspectives #
CBT
#
Cognitive
behavioural
therapy
#myths around anxiety #mindset #hope #faith #empathy #support #medical help #mental health issues #positive mind set #personal experience #face it fight with it #positivity #motivation
pratyaya_23
in
Anxiety and Depression Support
2 years ago
RLS - Q&A
Hi RLS survivors I am continuing my Pregabalin journey and wanted to check in with this community to ask out loud various questions circling around my head. The good news is that Pregabalin is making a difference. I get some relief from jumpy legs at night even on a low dose (75mg) What I am experiencing
Hi RLS survivors I am continuing my Pregabalin journey and wanted to check in with this community to ask out loud various questions circling around my head. The good news is that Pregabalin is making a difference. I get some relief from jumpy legs at night even on a low dose (75mg) What I am experiencing
careerSquirrel
in
Restless Legs Syndrome
8 months ago
Synthetic Hormones, Chemo & Radiotherapy
Hello, I am 60 years old, female,in the U.K., have had Primary Myelofibrosis for 20 years, treated with Aspirin & HU until recently, now switched to Anagrelide. I have recently been diagnosed with breast cancer, due to have lumpectomy next month, then there will be decisions to make about further treatments
Hello, I am 60 years old, female,in the U.K., have had Primary Myelofibrosis for 20 years, treated with Aspirin & HU until recently, now switched to Anagrelide. I have recently been diagnosed with breast cancer, due to have lumpectomy next month, then there will be decisions to make about further treatments
CraftySpider
in
MPN Voice
8 months ago
Orgovyx Insurance Approval
Anyone who is not on Medicare but relying on private insurance in getting approval for Orgovyx? I really want to avoid Lupron or Eligard since I take two blood pressure meds, one statin and Metformin for type 2 diabetes already. Plus, I have heard nothing but bad things about both. Yes, I realize
Anyone who is not on Medicare but relying on private insurance in getting approval for Orgovyx? I really want to avoid Lupron or Eligard since I take two blood pressure meds, one statin and Metformin for type 2 diabetes already. Plus, I have heard nothing but bad things about both. Yes, I realize
805guy
in
Prostate Cancer Network
8 months ago
Thyroid medication and side effects 😢
Hi everyone ❤️ I hope I can pick the brains of all you fellow members 🧠 this last 2 weeks have been the worst on this dose increase of Roma T3, i increased about 6 week's ago from 20mg to 25mg. Ive always had stomach and bowle issues on all the thyroid medication I've been on, from tablets to capsules
Hi everyone ❤️ I hope I can pick the brains of all you fellow members 🧠 this last 2 weeks have been the worst on this dose increase of Roma T3, i increased about 6 week's ago from 20mg to 25mg. Ive always had stomach and bowle issues on all the thyroid medication I've been on, from tablets to capsules
birkie
in
Thyroid UK
10 months ago
HRT question.
Hi, I’m been on HRT for about 5 weeks now but my anxiety has just got worse. I’m having hot flashes today too, i feel my head is about to explode. Shouldn’t I be feeling a little bit better by now or is it too soon. Any thoughts please?
Hi, I’m been on HRT for about 5 weeks now but my anxiety has just got worse. I’m having hot flashes today too, i feel my head is about to explode. Shouldn’t I be feeling a little bit better by now or is it too soon. Any thoughts please?
BjAli
in
Menopause and Perimenopause Support
8 months ago
undiagnosed, unwell and with other autoimmune conditions .
hello, new here but user of HU due to other diagnosed AI condition in rheumatology field. Tests just starting to eliminate conditions, gastroscopy found nothing, abdominal scan pending, omeprazole prescribed. Existing condition Adult onset Stills Disease (1979) med free except pain relief, constant
hello, new here but user of HU due to other diagnosed AI condition in rheumatology field. Tests just starting to eliminate conditions, gastroscopy found nothing, abdominal scan pending, omeprazole prescribed. Existing condition Adult onset Stills Disease (1979) med free except pain relief, constant
Stills
in
Thyroid UK
8 months ago
Hot flushes and night sweats
Hi everyone I would like some advice please. I had been in HRT for 22 years (implants) but when I moved 8 years ago I couldn’t find a gynaecologist to do implants so I decided to stop using HRT. All was fine for 4/5years then I suddenly start having flushes during the day and night sweats which have
Hi everyone I would like some advice please. I had been in HRT for 22 years (implants) but when I moved 8 years ago I couldn’t find a gynaecologist to do implants so I decided to stop using HRT. All was fine for 4/5years then I suddenly start having flushes during the day and night sweats which have
Allot
in
Menopause and Perimenopause Support
8 months ago
The PSP & CBD Ice Cream Challenge 2023 Holdout
The PSP & CBD Ice Cream Challenge 2023 Holdout Okay admit it. How many of us have found ourselves in front of the refrigerator/freezer after we've gone to bed? Those midnight or later stomach grumblings won't let you sleep until they're satisfied. As so often depicted on TV commercials and television
The PSP & CBD Ice Cream Challenge 2023 Holdout Okay admit it. How many of us have found ourselves in front of the refrigerator/freezer after we've gone to bed? Those midnight or later stomach grumblings won't let you sleep until they're satisfied. As so often depicted on TV commercials and television
daddyt
in
PSP Association
11 months ago
hormones
Any post-menopausal women out there? My symptoms of ADD -for me it’s really MDD motivation deficit disorder, have gotten much worse over the past couple of years. I am looking to go on Hormone Replacement Therapy- was wondering if anyone has experienced this and did it help?
Any post-menopausal women out there? My symptoms of ADD -for me it’s really MDD motivation deficit disorder, have gotten much worse over the past couple of years. I am looking to go on Hormone Replacement Therapy- was wondering if anyone has experienced this and did it help?
ADDSufferer
in
CHADD's Adult ADHD Support
8 months ago
New Study - Men on adt for 6 months- 75% recover Testosterone BUT median time is 18 MONTHS!!!????-Orgovyxx may be different? Yes I Hope??
New Meta Analysis From Marcap Consortium says :
Men on adt for 6 months -75% recover Testosterone BUT the median recovery time is 18 months !!!
AND THE OTHER 25% -NEVER!??
I TOOK ORGOVYXX FOR 4 MONTHS ???? THEY SAY IT MAY BE DIFFERENT FOR ORGOVYXX??
P.S. Any studies
New Meta Analysis From Marcap Consortium says :
Men on adt for 6 months -75% recover Testosterone BUT the median recovery time is 18 months !!!
AND THE OTHER 25% -NEVER!??
I TOOK ORGOVYXX FOR 4 MONTHS ???? THEY SAY IT MAY BE DIFFERENT FOR ORGOVYXX??
P.S. Any studies
JWS13
in
Advanced Prostate Cancer
7 months ago
Ten Months After All Treatments Ended
My Oncologist stopped my Eligard injections in October of 2022. My August 2023 bloodwork shows that my testosterone has risen from 2.0 to 10.0 in that time. My PSA was <0.1 ten months ago and is now 0.1 (Canadian units). I know that this cancer is a long game, but given my diagnosis in 2020, I am happy
My Oncologist stopped my Eligard injections in October of 2022. My August 2023 bloodwork shows that my testosterone has risen from 2.0 to 10.0 in that time. My PSA was <0.1 ten months ago and is now 0.1 (Canadian units). I know that this cancer is a long game, but given my diagnosis in 2020, I am happy
TottenhamMan
in
Advanced Prostate Cancer
8 months ago
Supraphysiological Androgens [SPA] Promote Tumor Suppressive Activity of the AR Through cMYC Repression and Recruitment of the DREAM Complex
New study [1]. I have struggled to understand how Denmeade’s BAT (Bipolar Androgen Therapy) depends on supraphysiological levels of androgen (testosterone = ~2,000 ng/dL), considering that Morgentaler’s saturation model has it that androgen receptors [ARs] have all the testosterone they can use at
New study [1]. I have struggled to understand how Denmeade’s BAT (Bipolar Androgen Therapy) depends on supraphysiological levels of androgen (testosterone = ~2,000 ng/dL), considering that Morgentaler’s saturation model has it that androgen receptors [ARs] have all the testosterone they can use at
pca2004
in
Fight Prostate Cancer
10 months ago
RLS and HRT
I’ve always suffered mild rls in the evenings but some leg lifts and going to sleep stopped it , last few months it’s severe , I was up every half hour all last night walking the floors with restless legs , arms and stomach , my mind going haywire 🥴I think it could be linked to HRT and menopause but
I’ve always suffered mild rls in the evenings but some leg lifts and going to sleep stopped it , last few months it’s severe , I was up every half hour all last night walking the floors with restless legs , arms and stomach , my mind going haywire 🥴I think it could be linked to HRT and menopause but
Ronniebongo
in
Restless Legs Syndrome
8 months ago
Extreme sweats will they diminish; Zitiga is it worth it
I am 74 years of age and was initially diagnosed with prostate cancer Gleason 5+4 2011. I did not want and have had no surgery, no radiation and no treatment until starting ADT July, 2023. March of this year, I was hospitalized for what turned out to be kidney failure do to urine backing up into
I am 74 years of age and was initially diagnosed with prostate cancer Gleason 5+4 2011. I did not want and have had no surgery, no radiation and no treatment until starting ADT July, 2023. March of this year, I was hospitalized for what turned out to be kidney failure do to urine backing up into
Falcon10
in
Advanced Prostate Cancer
8 months ago
Novel brain penetrant capsids for Parkinson’s disease gene therapy
https://www.youtube.com/watch?v=7f-TBoq0TLo
https://www.youtube.com/watch?v=7f-TBoq0TLo
Hidden
in
Cure Parkinson's
1 year ago
Coincidentally ...
.. a new study on CVD risk factors in men with PCa [1]: "
The Burden of Uncontrolled Cardiovascular Risk Factors in Men With Prostate Cancer: A RADICAL-PC Analysis
" The study found that most men with PCa have modifiable CVD risk factors. Although the authors recognize that CVD risk is
.. a new study on CVD risk factors in men with PCa [1]: "
The Burden of Uncontrolled Cardiovascular Risk Factors in Men With Prostate Cancer: A RADICAL-PC Analysis
" The study found that most men with PCa have modifiable CVD risk factors. Although the authors recognize that CVD risk is
pca2004
in
Fight Prostate Cancer
8 months ago
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