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Gamma Delta CAR T for Bone Metastatic Prostate Cancer: first trial at Moffit
Another trial of something that targets bone metastasis, and works even better if you are under zolendronate . "Most importantly, gamma delta T cells are unique in that they are most efficient when combined with a drug (zoledronate) that is commonly used to protect the bone in patients with bone metastatic
Another trial of something that targets bone metastasis, and works even better if you are under zolendronate . "Most importantly, gamma delta T cells are unique in that they are most efficient when combined with a drug (zoledronate) that is commonly used to protect the bone in patients with bone metastatic
Maxone73
in
Advanced Prostate Cancer
2 months ago
Clinical trial update
Trial Drugs: Inavolisib and Giredestrant. Today was my second set of scans (every 8 weeks) and the results of the chest CT and Bone scans were great, nothing new, all stable and NED in lungs. The abdomen CT showed slight increase in the size of my liver lesions. I am ER+, HER2 low +1, PR-, AR+, with
Trial Drugs: Inavolisib and Giredestrant. Today was my second set of scans (every 8 weeks) and the results of the chest CT and Bone scans were great, nothing new, all stable and NED in lungs. The abdomen CT showed slight increase in the size of my liver lesions. I am ER+, HER2 low +1, PR-, AR+, with
Trissh
in
SHARE Metastatic Breast Cancer
2 months ago
My prostate history
In 2020 at age 66 years I was diagnosed with prostate cancer. DRE was negative. TRUS Prostate biopsy positive: Gleason score 7 (3+4) left lateral base, Gleason score 6 (3+3) left lateral apex. Treatment plan: Active Surveillance. In February 2024, Rise in PSA 12.8, compared to 5.8 six months earlier
In 2020 at age 66 years I was diagnosed with prostate cancer. DRE was negative. TRUS Prostate biopsy positive: Gleason score 7 (3+4) left lateral base, Gleason score 6 (3+3) left lateral apex. Treatment plan: Active Surveillance. In February 2024, Rise in PSA 12.8, compared to 5.8 six months earlier
BobDad
in
Prostate Cancer Network
2 months ago
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Nagalase count
My nagalase count is declining. 1.55 -1.37 - 1.12 today. The Clioquinol +zinc +ivermicetin is still working on the way to zero. PSA is steady at 32 Nagalase is an enzyme that cancer cells produce to protect themselves from the immune system.
My nagalase count is declining. 1.55 -1.37 - 1.12 today. The Clioquinol +zinc +ivermicetin is still working on the way to zero. PSA is steady at 32 Nagalase is an enzyme that cancer cells produce to protect themselves from the immune system.
agnut
in
Fight Prostate Cancer
2 months ago
Side effects from Xtandi monotherapy?
after failing multiple times on regular ADT plus SBRT and finally failing LU– 177 and Provenge, my PSA went on the rise again. I’ve been on mono Xtando for six weeks and not feeling well despite trying to exercise heavily. Going in for bloodwork tomorrow. What kind of labs should I ask for? Anyone
after failing multiple times on regular ADT plus SBRT and finally failing LU– 177 and Provenge, my PSA went on the rise again. I’ve been on mono Xtando for six weeks and not feeling well despite trying to exercise heavily. Going in for bloodwork tomorrow. What kind of labs should I ask for? Anyone
SViking
in
Advanced Prostate Cancer
2 months ago
What is Your Opinion on Docetaxel Added to Doublet Therapy for Early Oligorecurrent Metaststic M1a Prostate Cancer?
Hello, I have touched on this subject before, but it is something that is nagging at me and giving me some sleepless nights. My husband’s bio is updated for reference. At one year post prostatectomy with Stage 3b, he rose from 0.06 to 0.273 in three mos. At psa of 0.16 , a PSMA scan showed three sub
Hello, I have touched on this subject before, but it is something that is nagging at me and giving me some sleepless nights. My husband’s bio is updated for reference. At one year post prostatectomy with Stage 3b, he rose from 0.06 to 0.273 in three mos. At psa of 0.16 , a PSMA scan showed three sub
103532
in
Advanced Prostate Cancer
2 months ago
Opinions on my 2nd MRI results
Hello, I just received the results from 2nd MRI (results below and photos in reply), previous one was from Jan/2023 (results in bio). Having been on these forums for almost two years now, and in AS at UCLA, I highly value the opinion of those here that have similar experiences to my situation. Questions
Hello, I just received the results from 2nd MRI (results below and photos in reply), previous one was from Jan/2023 (results in bio). Having been on these forums for almost two years now, and in AS at UCLA, I highly value the opinion of those here that have similar experiences to my situation. Questions
Maximode
in
Prostate Cancer Network
2 months ago
Iodine and Povidone - A Chemistry Lesson
Over the years, we have seen many mentions of povidone-iodine. This video is the first time I have ever come across a proper explanation as to why povidone-iodine is chosen! It then continues with its aim of extracting pure iodine from povidone-iodine. The video could be very boring if you are
Over the years, we have seen many mentions of povidone-iodine. This video is the first time I have ever come across a proper explanation as to why povidone-iodine is chosen! It then continues with its aim of extracting pure iodine from povidone-iodine. The video could be very boring if you are
helvella
Thyroid UK
in
Thyroid UK
2 months ago
When is PARP introduced?
Hi My husband is currently on triple therapy ( Docetaxel chemo , Zoladex every 3 months and nubeqa) he has one more chemo round left next week. He is responding well so far as PSA is declining ( see profile for PSA) . I have seen some men are talking a PARP inhibitor and nubeqa and zoladex ( or ADT
Hi My husband is currently on triple therapy ( Docetaxel chemo , Zoladex every 3 months and nubeqa) he has one more chemo round left next week. He is responding well so far as PSA is declining ( see profile for PSA) . I have seen some men are talking a PARP inhibitor and nubeqa and zoladex ( or ADT
positive-thinking
in
Advanced Prostate Cancer
2 months ago
Son of a Fighter
Hello dear community, hope everything is well with all of you and your families. Im Rick the son of a 55 year old father that recently got diagnosed with Prostate Cancer Stage 4. At first he was misdiagnosed by our community urologist as a bladder cancer and after going with the TURBT procedure the biopsy
Hello dear community, hope everything is well with all of you and your families. Im Rick the son of a 55 year old father that recently got diagnosed with Prostate Cancer Stage 4. At first he was misdiagnosed by our community urologist as a bladder cancer and after going with the TURBT procedure the biopsy
lp1312
in
Advanced Prostate Cancer
2 months ago
Radiation 10+ years after initial imrt
Psma detected a small area of cancer in what is left of my prostate…..psa of 20 at that time. After 3 months of eligard ,abiraterone and prednisone dropped to 0.04. MO and local radiologic oncologist are recommending a consult at MSK for tx of this area by whatever means might be the most safe and
Psma detected a small area of cancer in what is left of my prostate…..psa of 20 at that time. After 3 months of eligard ,abiraterone and prednisone dropped to 0.04. MO and local radiologic oncologist are recommending a consult at MSK for tx of this area by whatever means might be the most safe and
Tommyj2
in
Advanced Prostate Cancer
2 months ago
PSMA Pet Scan results
Diagnosed with prostate cancer with 1 lesion Gleason 7 (4+3). Have had MRI, biopsy and just completed PSMA Pet Scan. I see my doctor next week. I received the results and surprised to show some uptake in a lymph node. There is focal avid uptake noted in the anterior peripheral zone of the prostate
Diagnosed with prostate cancer with 1 lesion Gleason 7 (4+3). Have had MRI, biopsy and just completed PSMA Pet Scan. I see my doctor next week. I received the results and surprised to show some uptake in a lymph node. There is focal avid uptake noted in the anterior peripheral zone of the prostate
traversetom
in
Advanced Prostate Cancer
3 months ago
Expectations
I have undergone 45 radiation treatments and am on my last month of Eligard. PSA is undetectable and my T is barely existent. No mets detected on prior pet scans. My Urologist and Oncologist are giving me congrats. I understand this is probably a temporary remission (g 4+3 - stage 2/3) but I wonder
I have undergone 45 radiation treatments and am on my last month of Eligard. PSA is undetectable and my T is barely existent. No mets detected on prior pet scans. My Urologist and Oncologist are giving me congrats. I understand this is probably a temporary remission (g 4+3 - stage 2/3) but I wonder
Eadgbe
in
Advanced Prostate Cancer
3 months ago
Waiting for me to die
Just wondering if anyone else has experienced this. Sometimes i get the feeling that friends and family members are waiting for me to die. I was diagnosed stage 4b metastasis in January 2021 and have been on treatment Lupron and Xtandi since April 2021 3 years now. From an outward appearance I don't
Just wondering if anyone else has experienced this. Sometimes i get the feeling that friends and family members are waiting for me to die. I was diagnosed stage 4b metastasis in January 2021 and have been on treatment Lupron and Xtandi since April 2021 3 years now. From an outward appearance I don't
rogerandme
in
Advanced Prostate Cancer
3 months ago
Aquablation with APC
Hi there - does anyone here have experience with an aquablation procedure to improve urinary symptoms? My father is considering it. He has been on doublet therapy for 1.5 years, his PSA recently started to tick up a little. It's been difficult to get a clear answer on whether the procedure poses any
Hi there - does anyone here have experience with an aquablation procedure to improve urinary symptoms? My father is considering it. He has been on doublet therapy for 1.5 years, his PSA recently started to tick up a little. It's been difficult to get a clear answer on whether the procedure poses any
nyc_son
in
Advanced Prostate Cancer
3 months ago
xtandi beginning to fail?
Seven months ago my PSA was 0.06. Three months ago PSA at my URO’s office was 0.11. I asked him if xtandi was beginning to fail me, he would not give me a answer. March 11th PSA at my MO’s office PSA was < 0.1. MO was happy with that number. I get checked again the 25th of this month at my URO. I
Seven months ago my PSA was 0.06. Three months ago PSA at my URO’s office was 0.11. I asked him if xtandi was beginning to fail me, he would not give me a answer. March 11th PSA at my MO’s office PSA was < 0.1. MO was happy with that number. I get checked again the 25th of this month at my URO. I
Echotango51
in
Advanced Prostate Cancer
3 months ago
New insight into combating drug-resistant prostate cancer
https://www.sciencedaily.com/releases/2024/04/240410112742.htm?utm_medium=email&utm_source=rasa_io&utm_campaign=newsletter Is there a currently available way to apply this treatment concept? New research sheds light on the significance of the glucocorticoid receptor in drug-resistant prostate cancer
https://www.sciencedaily.com/releases/2024/04/240410112742.htm?utm_medium=email&utm_source=rasa_io&utm_campaign=newsletter Is there a currently available way to apply this treatment concept? New research sheds light on the significance of the glucocorticoid receptor in drug-resistant prostate cancer
GeorgeGlass
in
Advanced Prostate Cancer
3 months ago
What does it mean?
I'm slightly embarrassed to be asking strangers on the internet, but I'm a little frustrated by the lack of information given by the doctors. My dad (63) just got diagnosed - Gleason score 8 - and after a new scan they've concluded there's two mets - one in the pelvic lymph node and one in the seminal
I'm slightly embarrassed to be asking strangers on the internet, but I'm a little frustrated by the lack of information given by the doctors. My dad (63) just got diagnosed - Gleason score 8 - and after a new scan they've concluded there's two mets - one in the pelvic lymph node and one in the seminal
TerribleAtInternet
in
Advanced Prostate Cancer
3 months ago
Oil of Evening Primrose
I had a lumpectomy last May. It was a small ductal carcinoma which was invasive. I went on to have Radiotherapy and started a five year course of Letrozole. I developed bad joint pain and I had a month off to see if the Letrozole was the culprit. It was better but not gone. The oncology nurse suggested
I had a lumpectomy last May. It was a small ductal carcinoma which was invasive. I went on to have Radiotherapy and started a five year course of Letrozole. I developed bad joint pain and I had a month off to see if the Letrozole was the culprit. It was better but not gone. The oncology nurse suggested
Tabbycat64
in
My Breast Cancer Community
3 months ago
PSA, total
Hello. I know this forum is about advanced prostate cancer. I’m really hoping I’m not there yet. I had a RP June 2023 I just got the results from my forth PSA test the first three were a post prostatectomy PSA test and all three were 0.02 this last one was a PSA, total. That’s what the Urologist wanted
Hello. I know this forum is about advanced prostate cancer. I’m really hoping I’m not there yet. I had a RP June 2023 I just got the results from my forth PSA test the first three were a post prostatectomy PSA test and all three were 0.02 this last one was a PSA, total. That’s what the Urologist wanted
Elkguide
in
Advanced Prostate Cancer
3 months ago
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