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clinical trial: ATR inhibitor for ATM mutated solid tumors
in vivo and in vitro studies suggest that ATR inhibitors work better than PARP inhibitors for people with ATM gene mutations…but together they may work even better I hope to find more data about this clinical trial https://www.biospace.com/article/releases/aprea-therapeutics-announces-dosing-of-first-patient-in-phase
in vivo and in vitro studies suggest that ATR inhibitors work better than PARP inhibitors for people with ATM gene mutations…but together they may work even better I hope to find more data about this clinical trial https://www.biospace.com/article/releases/aprea-therapeutics-announces-dosing-of-first-patient-in-phase
Maxone73
in
Advanced Prostate Cancer
7 months ago
PA/stomach pain
Hi all, I’m so grateful for all of your support as I’ve started down this road. Got diagnosed with PA/AIG in the fall via an endoscopy. I am on B12 injections. My stomach pain has gotten steadily worse instead of better even though I am on a very restrictive diet. Is there any reason for me to believe
Hi all, I’m so grateful for all of your support as I’ve started down this road. Got diagnosed with PA/AIG in the fall via an endoscopy. I am on B12 injections. My stomach pain has gotten steadily worse instead of better even though I am on a very restrictive diet. Is there any reason for me to believe
Lhood08
in
Pernicious Anaemia Society
4 months ago
Orchidectomy vs ADT
For anyone who had the bilateral orchidectomy, I would like some advice for my husband. When was it done? Before or after BCR occurred? What are the side effects? Do you take any other ADT meds after? How is your QOL and is there anything you'd do differently. He had RP in Dec 2021. No other treatment
For anyone who had the bilateral orchidectomy, I would like some advice for my husband. When was it done? Before or after BCR occurred? What are the side effects? Do you take any other ADT meds after? How is your QOL and is there anything you'd do differently. He had RP in Dec 2021. No other treatment
tn12
in
Advanced Prostate Cancer
7 months ago
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Update – surgery tomorrow, then on to Xeloda
Hello all – hope that the new year is finding you all on a good journey to healing and wellness. I unfortunately have been in and out of the hospital for 21 days with seven new MRIs as they are trying to discover the root cause of my back pain and inability to walk. In addition to the extensive bone
Hello all – hope that the new year is finding you all on a good journey to healing and wellness. I unfortunately have been in and out of the hospital for 21 days with seven new MRIs as they are trying to discover the root cause of my back pain and inability to walk. In addition to the extensive bone
Saltandlight
in
SHARE Metastatic Breast Cancer
7 months ago
B12 deficiency: a hidden trigger of inflammation?
This was posted on the Pernicious Anaemia Society forum - but I thought it might be of interest to the many here who have inflammation. [i]News Release 17-Oct-2023[/i] [i]
B12 deficiency: a hidden trigger of inflammation?
[/i] [i]Peer-Reviewed Publication[/i] [i]Society of Chemical Industry[
This was posted on the Pernicious Anaemia Society forum - but I thought it might be of interest to the many here who have inflammation. [i]News Release 17-Oct-2023[/i] [i]
B12 deficiency: a hidden trigger of inflammation?
[/i] [i]Peer-Reviewed Publication[/i] [i]Society of Chemical Industry[
helvella
Thyroid UK
in
Thyroid UK
4 months ago
Other blood results
I now have more results Serum folate 14.3 (3.1-17.5) Ferritin 138 (13-150) Iron 14 (5-28) B12 280 (200-940) Since they are in the range ‘everything is normal’! The coeliac one was clear so I can now try gluten free for 3 months to see if it makes any changes. But I am still tired, muscle aches
I now have more results Serum folate 14.3 (3.1-17.5) Ferritin 138 (13-150) Iron 14 (5-28) B12 280 (200-940) Since they are in the range ‘everything is normal’! The coeliac one was clear so I can now try gluten free for 3 months to see if it makes any changes. But I am still tired, muscle aches
Purple450
in
Thyroid UK
4 months ago
Heart Issues post Ivor Lewis
Hi, wondering if any of you that have had the Ivor Lewis surgery have had heart issues post surgery? At 3 years post surgery I started having atrial fibralation. Now 5 years post surgery and the afib is worse but I also have Braychardia ( very low heart rate) Looks like I will need a cardiac ablation
Hi, wondering if any of you that have had the Ivor Lewis surgery have had heart issues post surgery? At 3 years post surgery I started having atrial fibralation. Now 5 years post surgery and the afib is worse but I also have Braychardia ( very low heart rate) Looks like I will need a cardiac ablation
Janashlin
in
Oesophageal & Gastric Cancer
7 months ago
B12 injections stopped by gp after 5 years treatment on nhs
I was diagnosed with chronic b12 deficiency years ago - my GP started giving me injections every 3 months and my nurse told me that it was for life. I’ve always eaten meat my whole life - so my deficiency was not caused by diet. They have stated that my deficiency is due to malabsorption, but my intrinsic
I was diagnosed with chronic b12 deficiency years ago - my GP started giving me injections every 3 months and my nurse told me that it was for life. I’ve always eaten meat my whole life - so my deficiency was not caused by diet. They have stated that my deficiency is due to malabsorption, but my intrinsic
LaraPA
in
Pernicious Anaemia Society
4 months ago
bumped up moms scans
So I had shared that her markers had went up last week. When she had the progression in July she also had a plural effusion. Which she’s had drained only twice in 6 months. But her ribs have started being sore. So she goes into tomorrow for ultra sound to see if the fluid has built back up. So her
So I had shared that her markers had went up last week. When she had the progression in July she also had a plural effusion. Which she’s had drained only twice in 6 months. But her ribs have started being sore. So she goes into tomorrow for ultra sound to see if the fluid has built back up. So her
Flower1513
in
SHARE Metastatic Breast Cancer
7 months ago
lung ca and Crizotinib
hi I had been actually diagnosed with leimyosarcoma in calf muscle two years ago and successfully it was surgically removed and later no chemo was given. However in my scans there was a lung lesion that was there is scans but it was missed and left untreated till it reached stage 4. Now that I have been
hi I had been actually diagnosed with leimyosarcoma in calf muscle two years ago and successfully it was surgically removed and later no chemo was given. However in my scans there was a lung lesion that was there is scans but it was missed and left untreated till it reached stage 4. Now that I have been
Hassan786
in
Lung Cancer Support
7 months ago
Taste Issues and finger neuropathy on Xtandi( enzalutamide) ?
In order to participate in a clinical trial (FOR46 at UCSF) I had to switch from Nubeqa (darolutamide) to enzalutamide. Previously on abiraterone. Did really well on both medications. Now 4 months on enzalutamide and my 5th research infusion, I'm experiencing some side effects. Trying to determine
In order to participate in a clinical trial (FOR46 at UCSF) I had to switch from Nubeqa (darolutamide) to enzalutamide. Previously on abiraterone. Did really well on both medications. Now 4 months on enzalutamide and my 5th research infusion, I'm experiencing some side effects. Trying to determine
bandgeek
in
Advanced Prostate Cancer
7 months ago
Nagalase count
My nagalase count is declining. 1.55 -1.37 - 1.12 today. The Clioquinol +zinc +ivermicetin is still working on the way to zero. PSA is steady at 32 Nagalase is an enzyme that cancer cells produce to protect themselves from the immune system.
My nagalase count is declining. 1.55 -1.37 - 1.12 today. The Clioquinol +zinc +ivermicetin is still working on the way to zero. PSA is steady at 32 Nagalase is an enzyme that cancer cells produce to protect themselves from the immune system.
agnut
in
Fight Prostate Cancer
4 months ago
My SCT journey continues
Hi all, not posted for a while but I am now at day+33 and finally starting to feel a bit normal again. I had very bad mucositis following sct and then problems with fluid retention due to all the IVs, mainly tpn as the ng feeding tube didn't stay in. Anyway looks like I'm going home on Friday so that's
Hi all, not posted for a while but I am now at day+33 and finally starting to feel a bit normal again. I had very bad mucositis following sct and then problems with fluid retention due to all the IVs, mainly tpn as the ng feeding tube didn't stay in. Anyway looks like I'm going home on Friday so that's
Flyingsteamer
in
MPN Voice
4 months ago
my cancer comic…
I’m a graphic designer who has done autobiographical comics for around 16 years, mostly about medical stuff (detached retina, thyroid surgery, a bad fall, gallbladder surgery…). Late last year I was diagnosed with prostate cancer. Just my prostate and some pelvic lymph nodes at this point, and awaiting
I’m a graphic designer who has done autobiographical comics for around 16 years, mostly about medical stuff (detached retina, thyroid surgery, a bad fall, gallbladder surgery…). Late last year I was diagnosed with prostate cancer. Just my prostate and some pelvic lymph nodes at this point, and awaiting
Jpburns
in
Advanced Prostate Cancer
7 months ago
Tall Cell Aggressive Papillary Thyroid Cancer
Interested in speaking with other Tall Cell Papillary Thyroid Cancer adults diagnosed in late that have both the BRAF V 600 and TERT gene. I have had a total thyroidechtomy 2/3 para thyroid out 85 nodes removed. RAI 150. Daily radiation for 8 weeks with one day a week chemo, 6 proton therapy. Now
Interested in speaking with other Tall Cell Papillary Thyroid Cancer adults diagnosed in late that have both the BRAF V 600 and TERT gene. I have had a total thyroidechtomy 2/3 para thyroid out 85 nodes removed. RAI 150. Daily radiation for 8 weeks with one day a week chemo, 6 proton therapy. Now
Portugal-2
in
Thyroid UK
7 months ago
Tall Cell Agressive Papillary Thyroid Cancer
Interested in speaking with other Tall Cell Papillary Thyroid Cancer adults diagnosed in late that have both the BRAF V 600 and TERT gene. I have had a total thyroidechtomy 2/3 para thyroid out 85 nodes removed. RAI 150. Daily radiation for 8 weeks with one day a week chemo, 6 proton therapy. Now have
Interested in speaking with other Tall Cell Papillary Thyroid Cancer adults diagnosed in late that have both the BRAF V 600 and TERT gene. I have had a total thyroidechtomy 2/3 para thyroid out 85 nodes removed. RAI 150. Daily radiation for 8 weeks with one day a week chemo, 6 proton therapy. Now have
Portugal-2
in
Thyroid Cancer Support
7 months ago
TSAT low but Ferritin fine/maybe high
Hi everyone, I do appreciate reading all of your posts and am sorry for how much suffering is connected to RLS. It's very encouraging to read about a number of people finding solutions to their RLS. I am seeing improvement but have some questions that I hope you can help me with: RLS has been a
Hi everyone, I do appreciate reading all of your posts and am sorry for how much suffering is connected to RLS. It's very encouraging to read about a number of people finding solutions to their RLS. I am seeing improvement but have some questions that I hope you can help me with: RLS has been a
b1interest
in
Restless Legs Syndrome
4 months ago
does anyone out there have histamine intolerance?
hi I’ve just changed from hydroxicarbamide to interferon. Seems ok, fingers crossed, but I also have histamine intolerance amd the absence of Hydroxicarbamide seems to be allowing my mast cells to have a high old time churning out histamine. Has anyone else experienced this? Louise
hi I’ve just changed from hydroxicarbamide to interferon. Seems ok, fingers crossed, but I also have histamine intolerance amd the absence of Hydroxicarbamide seems to be allowing my mast cells to have a high old time churning out histamine. Has anyone else experienced this? Louise
Loubprv
Volunteer
in
MPN Voice
4 months ago
Update and advice needed x
Thank you all for your lovely comments. CT scan result shows a small area on the outside of the bowel which needs further investigation. Really shocked to hear this! After the procedure had been told cancer removed. Has anybody had a similar experience? Oncologist unable to say if it’s ovarian/bowel
Thank you all for your lovely comments. CT scan result shows a small area on the outside of the bowel which needs further investigation. Really shocked to hear this! After the procedure had been told cancer removed. Has anybody had a similar experience? Oncologist unable to say if it’s ovarian/bowel
ORGM
in
My Ovacome
7 months ago
Help with results!
Hi everyone! Hoping that I can get some advice here. I was diagnosed 3 years ago with endo via laparoscopy. Most of the endo was found on my pouch of douglas and ureteral sacral ligaments. Unfortunately the operation wasn’t done by an endo specialist! I recently got referred to an endo centre as
Hi everyone! Hoping that I can get some advice here. I was diagnosed 3 years ago with endo via laparoscopy. Most of the endo was found on my pouch of douglas and ureteral sacral ligaments. Unfortunately the operation wasn’t done by an endo specialist! I recently got referred to an endo centre as
LJC1416
in
Endometriosis UK
4 months ago
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