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Patches (I'm depending on you, son)
Dated pop reference - sorry. While my research has continued, my oncologist has nothing to give me within the SOC to keep the PSA in check. Now I've witnessed another unwelcome visitor: facial hair (it only took me 70 yrs to start shaving....) Joking aside however, that means the T is on the rise.
Dated pop reference - sorry. While my research has continued, my oncologist has nothing to give me within the SOC to keep the PSA in check. Now I've witnessed another unwelcome visitor: facial hair (it only took me 70 yrs to start shaving....) Joking aside however, that means the T is on the rise.
CrocodileShoes
in
Advanced Prostate Cancer
6 months ago
Gynecomastia from ADT - how much?
Gynecomastia from ADT - how much? I am considering asking my oncologist for transdermal estrogn (TDE) therapy instead of Orgovyx to combat my prostate cancer. Since gynecomastia and breast pain are pretty much the only bad side effects from TDE and less troubling to me than metabolic disturbance,
Gynecomastia from ADT - how much? I am considering asking my oncologist for transdermal estrogn (TDE) therapy instead of Orgovyx to combat my prostate cancer. Since gynecomastia and breast pain are pretty much the only bad side effects from TDE and less troubling to me than metabolic disturbance,
Lost_Sheep
in
Prostate Cancer Network
6 months ago
Help and Advice
I have been suffering some time now ( years perhaps ) with debilitating symptoms such as exhaustion, puffy face, coldness, constipation, dry skin, hair shedding, muscle aches and more recently severe numbness and pins and needles in my hands. I thought this may be the onset on menopause as I am now
I have been suffering some time now ( years perhaps ) with debilitating symptoms such as exhaustion, puffy face, coldness, constipation, dry skin, hair shedding, muscle aches and more recently severe numbness and pins and needles in my hands. I thought this may be the onset on menopause as I am now
Sarageorge1971
in
Thyroid UK
6 months ago
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Are we on the right track?
Hi All, My husband, Pat (61) was diagnosed in late February with low grade metastatic PC. Gleason 9 grade 5. PSA 32. In a few small pelvic lymph nodes and a couple pelvic lesions. No other spread. PSMA pet scan detected this. We are working with a team and when we were told his diagnosis from his
Hi All, My husband, Pat (61) was diagnosed in late February with low grade metastatic PC. Gleason 9 grade 5. PSA 32. In a few small pelvic lymph nodes and a couple pelvic lesions. No other spread. PSMA pet scan detected this. We are working with a team and when we were told his diagnosis from his
Kathyford
in
Advanced Prostate Cancer
3 months ago
OS versus Testosterone Nadir - 5
This plot shows the Overall Survival Probability after RT and ADT, for Advance Prostate Cancer men, comparing two different ranges of testosterone nadir (< 10 ng/dL, and 10-20 ng/dL) after 11 years. The
best
outcomes
are significantly associated with a
lower testosterone nadir ( <
This plot shows the Overall Survival Probability after RT and ADT, for Advance Prostate Cancer men, comparing two different ranges of testosterone nadir (< 10 ng/dL, and 10-20 ng/dL) after 11 years. The
best
outcomes
are significantly associated with a
lower testosterone nadir ( <
janebob99
in
Advanced Prostate Cancer
6 months ago
OS versus Testosterone Nadir - 4
This plot shows the Overall Survival Probability after RT and ADT, for Advance Prostate Cancer men, comparing different levels of testosterone nadir (< 10 ng/dL, 10-20, and 20-50, The
best
outcomes
are significantly associated with a
lower testosterone nadir ( < 10 ng/dL).
[b
This plot shows the Overall Survival Probability after RT and ADT, for Advance Prostate Cancer men, comparing different levels of testosterone nadir (< 10 ng/dL, 10-20, and 20-50, The
best
outcomes
are significantly associated with a
lower testosterone nadir ( < 10 ng/dL).
[b
janebob99
in
Advanced Prostate Cancer
6 months ago
PSA relapse rate vs testosterone nadir - 3
This plot shows the PSA relapse rate after RT and ADT, for Intermediate and High Risk men, comparing different levels of testosterone nadir ( 50 nd/dL). (ref: 2019) The
best
outcomes
are significantly associated with a
lower testosterone nadir ( < 20 ng/dL),
and the relationship
This plot shows the PSA relapse rate after RT and ADT, for Intermediate and High Risk men, comparing different levels of testosterone nadir ( 50 nd/dL). (ref: 2019) The
best
outcomes
are significantly associated with a
lower testosterone nadir ( < 20 ng/dL),
and the relationship
janebob99
in
Advanced Prostate Cancer
6 months ago
PSA Survival vs Testosterone Nadir - 2
This plot shows the Biochemical Relapse Free Survival after RT and ADT, after 10 years , for Intermediate and High Risk men, comparing different levels of testosterone nadir ( 50 nd/dL). (ref: 2019) The
best
outcomes
are significantly associated with a
lower testosterone nadir ( < 20
This plot shows the Biochemical Relapse Free Survival after RT and ADT, after 10 years , for Intermediate and High Risk men, comparing different levels of testosterone nadir ( 50 nd/dL). (ref: 2019) The
best
outcomes
are significantly associated with a
lower testosterone nadir ( < 20
janebob99
in
Advanced Prostate Cancer
6 months ago
PSA Survival vs Testosterone Nadir - 1
This plot shows the Biochemical Relapse Free Survival after RT and ADT, versus time for up to 18 years, for Intermediate and High Risk men, comparing different levels of testosterone nadir ( 50 nd/dL). (ref: 2019) The
best
outcomes
are significantly associated with a
lower testosterone
This plot shows the Biochemical Relapse Free Survival after RT and ADT, versus time for up to 18 years, for Intermediate and High Risk men, comparing different levels of testosterone nadir ( 50 nd/dL). (ref: 2019) The
best
outcomes
are significantly associated with a
lower testosterone
janebob99
in
Advanced Prostate Cancer
6 months ago
DENOSUNAB
I have stage 4 incurable lung cancerI have been on this drug for 20 months in respect of my bone cancer. My scans to date have all been stable and continue to show that the cancer has shrunk or disappeared to date. However, as my targeted therapy treatment (Brigatinib) is working, I am enquiring whether
I have stage 4 incurable lung cancerI have been on this drug for 20 months in respect of my bone cancer. My scans to date have all been stable and continue to show that the cancer has shrunk or disappeared to date. However, as my targeted therapy treatment (Brigatinib) is working, I am enquiring whether
Gymbuddie
in
The Roy Castle Lung Cancer Foundation
10 months ago
EBRT - Is it the right thing and what to expect?
After DX in November 2018 with Stage IV and Gleason of 5+4 and 4+5, and 5 years of ADT of Lupron (then Orgovyx), prednisone 5mg, and Zytiga 250mg with low fat breakfast, my PSA stayed stable at 0.4 or 0.5. At end of 2013, PSA started rising to latest value of 0.84. Had PSMA PET Scan March 5, 2024
After DX in November 2018 with Stage IV and Gleason of 5+4 and 4+5, and 5 years of ADT of Lupron (then Orgovyx), prednisone 5mg, and Zytiga 250mg with low fat breakfast, my PSA stayed stable at 0.4 or 0.5. At end of 2013, PSA started rising to latest value of 0.84. Had PSMA PET Scan March 5, 2024
JazzMan42
in
Advanced Prostate Cancer
5 months ago
Fed up at not being able to do basic stuff
Over last 2 years health wise gonw bad to worse. No energy little interest i. Going out or even getting dressed.I used to be very i dependent ie own diy. Cleani g shoppi g ect. Even had craft hobby.but now all i seemto want to do is sleep
Over last 2 years health wise gonw bad to worse. No energy little interest i. Going out or even getting dressed.I used to be very i dependent ie own diy. Cleani g shoppi g ect. Even had craft hobby.but now all i seemto want to do is sleep
lizaspo
in
British Liver Trust
8 months ago
radiation or no radiation
I Just updated my profile and am G-9 with PNI, IDC and lymphovascular invasion. Check 2 mutation as well but Decipher at .41. RP Dr V Patel march 2020 (T3b, negative margins and negative lymph nodes) and PSA undetectable until Sept 2023. Started at 0.021 and now Feb 22nd 2024 at 0.052. Seeing Dr
I Just updated my profile and am G-9 with PNI, IDC and lymphovascular invasion. Check 2 mutation as well but Decipher at .41. RP Dr V Patel march 2020 (T3b, negative margins and negative lymph nodes) and PSA undetectable until Sept 2023. Started at 0.021 and now Feb 22nd 2024 at 0.052. Seeing Dr
Peppertree602
in
Advanced Prostate Cancer
6 months ago
Early Results from Transdermal Estrogen PATCH trial - 2
Here's some charts comparing Lupron ADT to transdermal estrogen (TDE) therapy for High Risk and Very High Risk men with prostate cancer. The upper chart shows the percentage of men that have been castrated to a testosterone level < 50 ng/dL after 1 month of treatment. For Lupron, only 65% of HR/VHR
Here's some charts comparing Lupron ADT to transdermal estrogen (TDE) therapy for High Risk and Very High Risk men with prostate cancer. The upper chart shows the percentage of men that have been castrated to a testosterone level < 50 ng/dL after 1 month of treatment. For Lupron, only 65% of HR/VHR
janebob99
in
Prostate Cancer Network
6 months ago
Early Results from Transdermal Estrogen PATCH trial - 2
Here's some charts comparing Lupron ADT to transdermal estrogen (TDE) patch therapy for High Risk and Very High Risk men with prostate cancer. The upper chart shows the percentage of men that have been castrated to a testosterone level < 50 ng/dL after 1 month of treatment. For Lupron, 65% of HR/
Here's some charts comparing Lupron ADT to transdermal estrogen (TDE) patch therapy for High Risk and Very High Risk men with prostate cancer. The upper chart shows the percentage of men that have been castrated to a testosterone level < 50 ng/dL after 1 month of treatment. For Lupron, 65% of HR/
janebob99
in
Advanced Prostate Cancer
6 months ago
Early Results from Transdermal Estrogen PATCH trial
Here are some Early Results from the first year of the Transdermal Estrogen PATCH trial. References are available on their website at: http://patch.mrcctu.ucl.ac.uk. The cohort was men with High or Very High Risk prostate cancer. Stage T3 (73%) and Stage T4 (14%), baseline PSA = 35 ng/mL. The upper
Here are some Early Results from the first year of the Transdermal Estrogen PATCH trial. References are available on their website at: http://patch.mrcctu.ucl.ac.uk. The cohort was men with High or Very High Risk prostate cancer. Stage T3 (73%) and Stage T4 (14%), baseline PSA = 35 ng/mL. The upper
janebob99
in
Advanced Prostate Cancer
6 months ago
Early Results of Estrogen PATCH trial - 1
Here are some Early Results from the first year of the Transdermal Estrogen PATCH trial. References are available on their website at: http://patch.mrcctu.ucl.ac.uk. The cohort was men with High or Very High Risk prostate cancer. Stage T3 (73%) and Stage T4 (14%), baseline PSA = 35 ng/mL. The upper
Here are some Early Results from the first year of the Transdermal Estrogen PATCH trial. References are available on their website at: http://patch.mrcctu.ucl.ac.uk. The cohort was men with High or Very High Risk prostate cancer. Stage T3 (73%) and Stage T4 (14%), baseline PSA = 35 ng/mL. The upper
janebob99
in
Prostate Cancer Network
6 months ago
Results
Hi everyone I posted a couple of weeks ago and was advised to have bloods done. These are my results so hoping for further advice in supplementing or adjusting doseage. I currently take 50mcg Levothyroxine and 25mcg T3 daily. I also have B12 injections every 12wks. Latest B12 injection given day after
Hi everyone I posted a couple of weeks ago and was advised to have bloods done. These are my results so hoping for further advice in supplementing or adjusting doseage. I currently take 50mcg Levothyroxine and 25mcg T3 daily. I also have B12 injections every 12wks. Latest B12 injection given day after
Pixie50
in
Thyroid UK
6 months ago
here again needing advice!!
Had a private blood test with medicheck a few weeks ago. Here are the results: TSH 1.23 mu/L Normal range 0.27-4.2 mu/L Thyroxine 16.9 pmol/L Normal FT4 levels 12-22 pmol/L Triiodothyronine 4.2 pmol:L Normal levels FT3 3.1-6.8 pmol/L I am still feeling really rubbish on 100 microgram levothyroxine
Had a private blood test with medicheck a few weeks ago. Here are the results: TSH 1.23 mu/L Normal range 0.27-4.2 mu/L Thyroxine 16.9 pmol/L Normal FT4 levels 12-22 pmol/L Triiodothyronine 4.2 pmol:L Normal levels FT3 3.1-6.8 pmol/L I am still feeling really rubbish on 100 microgram levothyroxine
Vorney
in
Thyroid UK
6 months ago
Day 7 in HRT protocol = equivalent to what day in Natural cycle?
Hello my dear warriors, My clinic in Spain has recommended to go for a natural cycle rather than a HRT one this time. However my immune medicine is prescribed by the reproductive immunologist and to his protocol he has written : start Clexane and Prednisolone on day 7 of HRT. The nurses in his clinic
Hello my dear warriors, My clinic in Spain has recommended to go for a natural cycle rather than a HRT one this time. However my immune medicine is prescribed by the reproductive immunologist and to his protocol he has written : start Clexane and Prednisolone on day 7 of HRT. The nurses in his clinic
ValaI
in
Fertility Network UK
6 months ago
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