Heat up areas in liver

[ChrisVict]

Hi, well I got good news from onc that bone Mets decreasing and stable meanwhile scheduled for MRI for “liver heat up areas”I do not feel good about this because my tumor markers are up. Possibility of reaction to affinitor(?) anyone have comments. I understand liver is treatable but do you have to go in all the time for laser or direct infusion to area? More chemo, more exhaustion. Any insight helpful. My oncologists seemed optimistic liver mets is treatable but does anyone have experience on actual treatment?

[rsparks984]

Hello - I haven't been on affinitor but have been dealing with liver mets myself over the last couple of years. I have had to change treatments a few times to find what works. I haven't had any laser or any direct infusion - just treatment changes, I was diagnosed with liver mets in Oct 2018 and have had to try 5 different treatments, 2 of which have worked well on my liver and bone mets. It's all trial and error as we know. If I can be of any other help let me know. Best to you.

Rhea

[ChrisVict in reply to rsparks984]

Yes whic were the successful treatments and did you change because it stops working and has it kept the cancer in check? Did you have 1 spot or many spots?

[rsparks984 in reply to ChrisVict]

I had a couple of spots in the beginning. And yes, I changed meds because the treatments either didn't work or stopped working. One that did work was call Getatolosib - its a clinical trial. The other med, its the one I am currently on, is called sacituzumab govitecan. Its a drug that has been approved for triple-negative bc but is now in a trial for ER positive bc (which is what I have). I have had a good response. When drugs have failed I of course had more spots pop up on my liver. For me, watching tumor markers has been so important. A doctor might not think anything of a rise in a marker - to them it may seem to be at a reasonable level even though the number may be higher than the range that listed. But as the CEO of your own body, push for scans when you see those markers moving. I read where when tumor markers start going up it may take a few months for a scan to show. Just be your own advocate. I was diagnosed in Jan 2010 and metastatic Dec 2011. The one thing I learned early is being your own advocate. Everyone's body responds differently to treatment - so what works for one person may not work for another. Just don't get discouraged. If one doesn't work there are more options.

[ChrisVict in reply to rsparks984]

Where is your other Mets? I have bone mets in addition and feel like omg now I have to control 2 different growths and possibly a cocktail of drugs

[ChrisVict in reply to rsparks984]

So it’s trial and error and wait for MRI results I will ask about both these drugs

[blms in reply to rsparks984]

where do you live? I continue to look for local DC area support.Bonnie

[ChrisVict in reply to blms]

Sorry NY . I go to a psychologist 1x /month lately that is not enough and the share support for MBC there maybe a group that fits into your schedule has been very supportive. Your hospital or onc maybe able to help. I also use share help line I find it helps with the intermittent anxiety always a very understanding person on the other line.

[Topood]

I have liver Mets which they watch as they grow and shrink according to treatments I’m on, but I have had no therapy specifically for them. Sometimes I feel as if they make me a little uncomfortable, but that could be my imagination. Recently Xeloda has been working and they are shrinking...

[Red71 in reply to Topood]

I am also on Xeloda and it is working on my liver mets. Just had new scans this week so I’ll be able to report back if the Xeloda is continuing to work. I also have bone mets and they have been stable during this time.