Has anyone else had a loss if taste on Ibrance and Letrozole. I am on cycle 13, doing really good. I have just noticed things just don't taste good . Looking forward to hearing from you. I was diagnosed with bone mets right out of the gate Oct of 16. Horrible ! I had a spinal cord compression surgery couldn't do much....to much damage I had 10 radiation treatments for my spine, did a great job hardening the bones back up. In Nov of 16 I had a bilateral saddle pulmonary embolism I survived by the grace of God only. I was at my hospital when that hit me another gift from God. Woke up a couple days later in icu. I take a shot daily to keep my blood thin. Not bad. So grateful for so many things I know God ordained or I would not be here. Pretty sure I have the original tumor close to a year before I was diagnosed. Long story !!!! Many trips to my gp of 15 yrs. You are fine it is muscular not!!!. Prayers for you all sweet ladies!!!