Here are some posts from a maternity website talking about what sounds like primary RLS.
I have Restless Leg Syndrome and have suffered with it most of my life. It is worse during pregnancy. I have read that the MTHFR mutation is linked to RLS and am curious to see if any of you have it. I have noticed that my symptoms have improved since I started treatment for MTHFR and am hopeful that my RLS will go away.
I don't have Restless Leg Syndrome, but my doctor said 2000 I.U's of D3 is supposed to help. He had me try D3 for my leg cramps. I take 3000 I.U's at bedtime and it seems to help.
My beautiful daughters: Lily 9/24/09 & Charlotte 7/16/12
Ask me about MTHFR! I'm here to help
I get it occasionally and this homeopathic treatment is the only thing that helps me....
I have started MTHFR treatment lately (diagnosed with fertility testing with the A form, heterozygoes) and for the first time in my LIFE been able to have a solid night's sleep without a 20 mn very hot bath --or two or three...and stairs... and slow scissor kicks in the air lying on your back...I'm sure you know the drill... KissSo yes, I have the MTHFR and the MTHF supplements worked. Miraculously!!!!! Star (very high does folic acid and B12 and powdered magnesium helped somewhat in the past, but this is complete relief!) I think there is a great chance your RLS will go away and I am very happy for you!!!!!
I do wonder if some of those who get RLS in pregnancy might have the MTHFR defect themselves (rather common) and not know it. If this could be considered a diagnostic indicator, then they should get tested as not only they, but their baby, would benefit from them taking MTHF rather than folic acid. (Because people with MTHFR cannot process folic acid, so their babies may be at risk of several issues without proper supplementation.)
QUESTIONS for the EXPERTS (I hope we are not they, Carlypeach!): 1. I am early now in a pregnancy and am wondering if it is safe to be taking my working dose of 5mg of 5-MTHF every night before bed in one hit, or whether I should be spreading out the dosage across the day (which doesn't seem to work as well for sleep so I may need to increase it then) in order to not inundate the baby with a big dose at once? Or does MTHF have a gradual release?
2. Also, is it safe to use the presence of symptoms (in my case RLS) as a gauge for dosage even when pregnant? Or am I at risk of exposing the baby to too much? (yes, I realize this has not been adequately studied, so educated guesses are what I'm looking for, as I need to make regular decisions about it on some basis...)
One thing I forgot to mention was that I had read that RLS may be partly caused by low iron levels reaching the brain (so your blood levels may test ok even if it's not reaching your brain, I guess). I tried many iron supplements, but found Nature's Plus Hema-plex was the only one that worked for me. It has other things in it than iron, so perhaps it is that balance that helps it absorb, or perhaps it is that it is hi dose chelated iron. My iron levels have risen from low end to normal range on it, I tend to take it every other day, but have recently started splitting it in half. I would be curious if other RLS sufferers have had luck with chelated iron or this supplement in particular?
"What is Chelated Iron?
Chelated iron has undergone a process that binds it together with amino acids. This process makes the iron more similar to iron that occurs naturally in foods.
Why is Chelated Iron Used?
Some believe that the process of chelation makes the iron more easily absorbed through cell walls."
Read more: Chelated Iron Vs. Regular Iron Tablets | eHow.com ehow.com/facts_5625439_chel...
I just wanted to be clear that it is not JUST the MTHF that works on its own for me, but a combination of supplements in concert, and MTHF was just the last one I added the seemed to finally take it all away.