Vaginal suppositories

[grafixartist]

I have read about women who have used Valium vaginal suppositories for relief from pudendal nerve pain and pelvic floor dysfunction. My OBGYN is not familiar with this type of treatment and I have not been able to get a prescription to try it. I also read from one patient that she inserts a Valium tablet vaginally for relief. I do take Flexeril 10mg tablets upto 3 times per day as needed. Has anyone tried inserting Flexeril vaginally to see if it helps relax tight/spastic muscles?

[Rocky68]

Have used them for PN which was mostly confined to rectal and pereneum area. Used rectally at

Night before going to bed. It put me to sleep immediately. You can probably split tablets and be able to function during day. I would ask Dr about splitting them. Mine were compounded by specialist pharmacy. Rocky68

[grafixartist in reply to Rocky68]

I just wondered if a tablet would dissolve if inserted the same way it would if taken orally.

[Martinre in reply to Rocky68]

Hey can we be phone friends? My number is8643296683.I need support (someone to talk to about on)Can you call me today.

[Rxmom]

I’ve used Valium 10/lidocaine suppositories rectally twice a day for 3 yrs. truly would not be able to function without them. They are not commercially available so you need a compounding pharmacy & typically not covered - but if you provide a medically necessary letter to insurance, it may be covered (mine is now covered). There are many compounding pharmacies - healthy choice is great- they ship wherever & are very responsive.

I use a local nj compounding pharmacy - who will also ship overnight.

My condition has greatly improved using belbuca buccal 150mcg + suppositories + oxycodone (happy to say I am decreasing that one to just occasional use.

Happy to discuss. There are certain clauses in insurance coverage that may require looking at formula. I am pharmacist so I am familiar with formularies & payment.

But yes- Valium supp help w spasms.

I think the lido combo is synergistic & so much better than each ingredient alone.

You can use vaginally as well. Hope this is helpful.

[Konagirl60 in reply to Rxmom]

May I ask, what is your suppository made of? My pharmacist said I could not insert them rectally yet that is where my pain is? Thank you.

[Rxmom in reply to Konagirl60]

I’ll get the exact formula when I go to liberty drug in Chatham nj next tues or you could call them directly. The vaginal route is effective as well because it’s effect is pelvic floor muscles nearby. I just don’t like the melting effect which u don’t have rectally due to sphincter. Plus I think it “keeps” the medication in place for much longer effect. Again - my personal opinion.

My obgyn also orders Valium baclofen rectal suppositories - I get them mailed from healthy choice. Doesn’t work as well for me as Valium lidocaine combo but some ppl find relief w that combo - everyone seems has a different presentation of condition. Trial & error.

But look out if I EVER was told I couldn’t get my Val 10mg/lido 2% supp.

Some ppl Use the commercially available belladonna/opium (B&O)rectal supp. . I used them for years. They also worked very well but I wasn’t crazy about the belladonna anticholinergic side Effects (blurry vision etc) and preferred to stay away from the opium. But very very effective. Perrigo makes them so no need to compound but they do go out of stock occasionally. If my pain truly gets uncontrolled at some point, I would go back to B&O supp.

Does this help ? Lmk if other questions. And good luck.

[Konagirl60 in reply to Rxmom]

Hi. Thank you! I only use mine at night and for sleep as well as pain relief. Since starting legal THC oil, I am, out using them as often. Yes! I HATE drugs.

[Rxmom in reply to Konagirl60]

I just got approval for Med Mj in nj. Not really looking forward to using Bc I don’t want a Mj high. but willing to try - prob for bedtime. Is it working for pain? Or just sleep?

[CherylVacc in reply to Konagirl60]

I'm just starting my search for relief of Pudendal Neuralia, and was wondering what you mean by "tch oil" and how to use it. I live in NJ, and what you mention may be available to me, as weed is legal here 🙂

[Konagirl60 in reply to CherylVacc]

I don’t use THC ( legal in Canada if prescribed by a doctor ) anymore. It’s way too expensive. I don’t like to feel ‘ high’. I tried it for sleep due to intractable muscle spasms.

I’ve had the three surgeries I needed ( albeit all years too late ) and I’ve weaned off the Valium vaginal suppositories.

It appears from my experience that meds for nerve pain basically sedate you. At least they did for me.

What are you using now? BTW, I had severe entrapment of my right pudendal nerve. It was pinched in three spots.

[charlee4 in reply to Rxmom]

How much does the Val/lid cost out of pocket at your pharmacy?

[Rxmom in reply to charlee4]

$300 for 60 - one month supply

[charlee4 in reply to Rxmom]

Thank you.

[charlee4 in reply to charlee4]

Mine works to help me sleep. It must relax the muscles therefore affording pain relief as well. If we are allowed to name the company and type of product I take I can send you that. Someone please let me know whether I can do this and I will try and help, at least what works for me.

[Mistyamber in reply to charlee4]

Hi, just joined group, and wondered where I can get valium/lidocaine combo from, as having trouble sleeping. Thanks

[kalecolbe12 in reply to Rxmom]

The sound of the Belladonna and opium suppository scares me but if they work I will try them can you tell me how much they are and the website please?

[turkeybaster in reply to Rxmom]

I know this is an old post but wanted to share I also used B&O supps from Perrigo for about 15 years only for bad flares so taken at a time when i am in bed anyway .I am in Florida year 2023 and went to get prescription and Perrigo was bought out by another company(I always got mine through distributors compounding pharmacy regular pharmacies won't get it for years now) However you can not get any due to supply issues and the new company is the only one that makes them And they have no idea if they will ever be making them again on their website it says discontinued I spoke to the company myself.I also have Interstitial Cystitis and during a bad flare this was the only thing that worked.I am very stressed this was always my magic bullet from severe pain to pain free in less than an hour.I am now exploring other options.My urologist ordered Valium 2 mg suppositories (I have been on 2mg 3 x/day orally for many years hence the small starting dose ?)i don't think it is going to do anything compared to B&O supps.I still have 7 B&O left i am keeping in case but they expire soon

[charlee4 in reply to Rxmom]

What type of insurance do you have? I have Medicare with a supplement, but when I tried one compounded RX, it did not help me. I don't know what it was. How much does the month's supply cost when you pay out of pocket?

[anne77 in reply to Rxmom]

Hello RXmom--thanks for sharing! I am currently using suppositories that are 5% diazepam and 4% lidocaine. I have adjusted to using them during the day and am not even that sleepy anymore! This combo really just "takes the edge off" for me, and I was wondering if you are able to tolerate the10% diazepam during the daytime, or do you use only use at night? I definitely can't tolerate certain medications, and on a "quest" to find something to optimally manage the pain, but also give me the ability to function as best as possible! I live in FL and pay through the nose for BCBS insurance, but compounded medications aren't covered I will try to get a letter from any one of my specialists trying to appeal, so any suggestions on that would be greatly appreciated as well Thanks!!

[Arbust91 in reply to Rxmom]

Menaul Compounding pharmacy in Albuquerque makes them for $60 fro one month supply. Unfortunately Doctors in new Mexico can no longer prescribe any kind od bento's for chronic pain. I will be back on disability

[CynBen in reply to Arbust91]

I used to get mine compounded at Highland Pharmacy in ABQ. Hello fellow Burqueno! I think I paid abut $58 for 30, but that was 2 years ago.

[Debra13 in reply to Rxmom]

Hello

My name is Deb. Been suffering for 17 years with PD and was diagnosed last December with interstitial cystitis. I was curious about the suppositories you are using. I used vaginal diazepam. They just knocked me out the next day. Even at 5 mg. But you mentioned something different and also the pain medication is that compounded to the oxycodone. I’m hoping you can help. I don’t live to far I’m in New York so my doctors could probably get the compounding pharmacy you use for me to try this. You can private message me to let me know. Thank you and God bless. Debbie

[Arbust91 in reply to Debra13]

the drug is diazepam, it is sometimes mixed with baclofen as a suppository. You can not take narcotics vaginaly. It may take a few weeks to get over the sedation of the diazepam. You can take it before bed to start. All the pharmacist is doing is crushing the drug and mixing it with several things ( like glycerin, and silica gels) the distributes the drug evenly in each suppository and allows the drug to be absorbed over time as the secondary non active ingredients melt.

[carrotcake19 in reply to Debra13]

Hi Deb, Right now I am dealing with PD and vulvodynia. I am taking 5mg diazopam suppositories and lidocaine cream and have had thoughts that I might also have interstitial cystitis because my main symptoms of the last 6+ months are urgency and frequency. But the doctors at the heath system I go through currently are not going to test me because I was in too much pain just doing a catheterized urine sample, and they are scared I will freak out being tested for IC. How did they test you for interstitial cystitis? And what are your main symptoms if you don’t mind me asking?

[Debra13 in reply to carrotcake19]

Hello

I don’t mind at all. I was tested with a cystoscope under anesthesia it’s a camera that goes up the urethra and also with hydrodilation. They filled my bladder with fluid. Also I had two bladder biopsies done. It came back positive for as I was told the worst stage of interstitial cystitis to be in unfortunately. My symptoms sometimes are hard to distinguish between the PD and IC. but I think I can tell them apart now the the IC has gotten worse. First of all I feel like I have a urinary tract infection everyday. It’s constantly burning when I urinate. It trinkles out and I have a very hard time initiating my flow. I can not fully empty my bladder either and find myself having to manually help myself by pushing on my bladder while I urinate but it never really helps. The pain is mostly a burning pain but can be as severe as pain like kidney stone pain if I don’t watch my diet. Now I take bladder ease and an antihistamine for my treatment and I go for bladder installations like every 3 months. Not gonna lie to you. That’s not a pleasant procedure but it does help. The cystoscope isn’t pleasant either. If you have IC and Pudendal neuralgia it burns so bad to urinate the day of the test. Please feel free to ask me any questions and you can private message me if you would like also. Hope that helps. Deb.

[Alaarumh in reply to Rxmom]

Hi how are can you help me with the symptoms that you suffer from?

[Rxmom in reply to Alaarumh]

I sure can -

- it feels like a golf ball (Pressure like pain) is in rectum all day long. Pain is in one spot & never upon awakening but within minutes or if lucky, maybe an hour / it starts increasing & by late afternoon It skyrockets.

I developed ibs like symptoms which rob my am & set off spasms - this only after this PN started - I think it’s related to both meds & the nature of condition.

- ran thru all conservative approaches twice each: Botox, ganglion impar, nerve blocks, PT, acupuncture, chiro, every Med possible.

-ran thru all the rule out tests for other conditions w similar symptoms - pelvic congestion endo...

-fast forward 6 yrs & had neuro stim implanted end of 2019 w reposition surg early this year - bc leads migrated,; much better now but pain pattern remains. Intensity is lower and I continue to optimize stim program.

-still on a boatload if Med’s but at least now they make the diff from being in agony in bed for long stretches to very occasional episodes. I remain v limited in activity, sitting, etc but now that world has stopped w C-virus, there’s not a lot one can do but pray for many reasons.

Btw - I take oxy, belbulca, Valium, lidocaine supp & (Med MJ at bed only), & magnesium daily. Plus other rescue prn meds if it’s a bad day.

Welcome to Priv message me

And happy Easter & Passover to all

Best -

[DrOma in reply to Rxmom]

Rxmom, I was wondering if it's possible to replace the diazepam with (obviously dose-adjusted) alprazolam in a pessary? When diazepam is administered to me p.o., IV, or IM, I have the same SEVERE paradox reaction, so I'm guessing that administration route is not a factor; but I tolerate alprazolam very well.I was about to start researching the differences in composition, pH, and pharmacokinetics of alprazolam vs diazepam myself, when I came across your post, I'm hoping this was a "gift" and you happen to know if it's possible to use alprazolam instead?

Thank you so much!

[Rxmom]

Just another note - technically the Valium tabs should work but I find they do not dissolve & thus are not optimal but could give some relief. If you go this route, you may experience sedation initially. But like all these meds, it takes time tolerate side effects so suggest starting late in day, see how you do over a week or 2 then try am & pm. This is just my non professional suggestion - not meant to be a pharmacist reco.

[Rxmom]

Flexeril in any form turns me into Gumby. I use skelaxin orally prn.

The baclofen is a muscle relaxant .. as is flexeril & skelaxin. would have to research absorption etc. prob best to ask ur pelvic floor doc for actual clinical experience - these meds are all used off label so clin experience is likely more informative. The Valium /baclofen combo supp Work ok just not as well as Val/lido combo ... for me.

[Rocky68]

I've only taken suppositories and they were a waxy type compound and was told they would help more with spasms. I only took a few days as I had daytime spasms and could not function when I used them. I have since had a DRG Stimulator implant (read previous posts). It has offered 50% relief but still not able to sit for long periods of time it did help with spasms. Rocky68

[charlee4 in reply to Rocky68]

I am glad you had at least 50% reduction in pain after the DRG. I have tried that, but it did not work for me. I am looking for something that would work for me. I am curious about the Val/lid combo.

[stubb]

I am at present using Ketamine/lidocaine pessaries for pelvic pain especially in rectum and haven't noticed a big difference yet. You need a prescription from a specialist and it has to be made up at a compounding chemist. I have to pay $105- f0r a 30 day script so its not cheap but if it helps someone it would be worth the cost. Unfortunately the health fund I'm in don't recognise compounding chemists and don't pay anything towards it.

[hopeandchange]

Tried them not covered by insurance and they never helped. Good luck everyone is different

[Mftc]

I have used diazepam suppositories both vaginally and rectally. You need to see a urogynecologist. They will prescribe this for you it is a suppository made by a compound pharmacy you will not find it in your regular pharmacy. Also a myofascial release therapist helps with all pelvic problems and pain

[jerszy]

I'm a male with pelvic pain and have been prescribed valium with baclofen (a muscle relaxant) suppositories anally. I do get some relief. CBD might help as well. Good Luck!

[kalecolbe12 in reply to jerszy]

Hi ,I was just wondering how you are coming on with your pelvic pain?is it rectal and have you been diagnosed with pelvic floor dysfunction?any ne treatments/meds etc??

[kalecolbe12]

Some people make their own with 10 mg Valium and coconut oil

[kalecolbe12]

I know it's been a year since this post but I also take Flexeril 5 mg as needed ...I took them for 4 months straight 3 times a day and they have helped a lot...I take them as needed for pain flares...doc also gave me gabapentin but didn't try them yet...I was wondering how long you have taken the Flexeril and if we can take it long term even though they say it shouldn't be taken long term....and what kind of doctor prescribed it for you?

[Jackipear]

Hi this may be a little late however I have been using Valium / baclofen suppositories for a year now the dosage 5 mg of Valium and 4 of baclofen. Recently have increased dosage to 10 mg Valium 8 baclofen and 15 of ketamine I use these for pelvic floor dysfunction and endometriosis. They work fairly well - were prescribed by my GYN and have to have them filed at a compound pharmacy.