Pelvic Pain Support Network
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Vaginal suppositories

I have read about women who have used Valium vaginal suppositories for relief from pudendal nerve pain and pelvic floor dysfunction. My OBGYN is not familiar with this type of treatment and I have not been able to get a prescription to try it. I also read from one patient that she inserts a Valium tablet vaginally for relief. I do take Flexeril 10mg tablets upto 3 times per day as needed. Has anyone tried inserting Flexeril vaginally to see if it helps relax tight/spastic muscles?

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Have used them for PN which was mostly confined to rectal and pereneum area. Used rectally at

Night before going to bed. It put me to sleep immediately. You can probably split tablets and be able to function during day. I would ask Dr about splitting them. Mine were compounded by specialist pharmacy. Rocky68

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I just wondered if a tablet would dissolve if inserted the same way it would if taken orally.

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I’ve used Valium 10/lidocaine suppositories rectally twice a day for 3 yrs. truly would not be able to function without them. They are not commercially available so you need a compounding pharmacy & typically not covered - but if you provide a medically necessary letter to insurance, it may be covered (mine is now covered). There are many compounding pharmacies - healthy choice is great- they ship wherever & are very responsive.

I use a local nj compounding pharmacy - who will also ship overnight.

My condition has greatly improved using belbuca buccal 150mcg + suppositories + oxycodone (happy to say I am decreasing that one to just occasional use.

Happy to discuss. There are certain clauses in insurance coverage that may require looking at formula. I am pharmacist so I am familiar with formularies & payment.

But yes- Valium supp help w spasms.

I think the lido combo is synergistic & so much better than each ingredient alone.

You can use vaginally as well. Hope this is helpful.

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May I ask, what is your suppository made of? My pharmacist said I could not insert them rectally yet that is where my pain is? Thank you.

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I’ll get the exact formula when I go to liberty drug in Chatham nj next tues or you could call them directly. The vaginal route is effective as well because it’s effect is pelvic floor muscles nearby. I just don’t like the melting effect which u don’t have rectally due to sphincter. Plus I think it “keeps” the medication in place for much longer effect. Again - my personal opinion.

My obgyn also orders Valium baclofen rectal suppositories - I get them mailed from healthy choice. Doesn’t work as well for me as Valium lidocaine combo but some ppl find relief w that combo - everyone seems has a different presentation of condition. Trial & error.

But look out if I EVER was told I couldn’t get my Val 10mg/lido 2% supp.

Some ppl Use the commercially available belladonna/opium (B&O)rectal supp. . I used them for years. They also worked very well but I wasn’t crazy about the belladonna anticholinergic side Effects (blurry vision etc) and preferred to stay away from the opium. But very very effective. Perrigo makes them so no need to compound but they do go out of stock occasionally. If my pain truly gets uncontrolled at some point, I would go back to B&O supp.

Does this help ? Lmk if other questions. And good luck.

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Hi. Thank you! I only use mine at night and for sleep as well as pain relief. Since starting legal THC oil, I am, out using them as often. Yes! I HATE drugs.

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I just got approval for Med Mj in nj. Not really looking forward to using Bc I don’t want a Mj high. but willing to try - prob for bedtime. Is it working for pain? Or just sleep?

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How much does the Val/lid cost out of pocket at your pharmacy?

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$300 for 60 - one month supply

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Thank you.

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Mine works to help me sleep. It must relax the muscles therefore affording pain relief as well. If we are allowed to name the company and type of product I take I can send you that. Someone please let me know whether I can do this and I will try and help, at least what works for me.

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What type of insurance do you have? I have Medicare with a supplement, but when I tried one compounded RX, it did not help me. I don't know what it was. How much does the month's supply cost when you pay out of pocket?

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Hello RXmom--thanks for sharing! I am currently using suppositories that are 5% diazepam and 4% lidocaine. I have adjusted to using them during the day and am not even that sleepy anymore! This combo really just "takes the edge off" for me, and I was wondering if you are able to tolerate the10% diazepam during the daytime, or do you use only use at night? I definitely can't tolerate certain medications, and on a "quest" to find something to optimally manage the pain, but also give me the ability to function as best as possible! I live in FL and pay through the nose for BCBS insurance, but compounded medications aren't covered:( I will try to get a letter from any one of my specialists trying to appeal, so any suggestions on that would be greatly appreciated as well:) Thanks!!

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Just another note - technically the Valium tabs should work but I find they do not dissolve & thus are not optimal but could give some relief. If you go this route, you may experience sedation initially. But like all these meds, it takes time tolerate side effects so suggest starting late in day, see how you do over a week or 2 then try am & pm. This is just my non professional suggestion - not meant to be a pharmacist reco.

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Flexeril in any form turns me into Gumby. I use skelaxin orally prn.

The baclofen is a muscle relaxant .. as is flexeril & skelaxin. would have to research absorption etc. prob best to ask ur pelvic floor doc for actual clinical experience - these meds are all used off label so clin experience is likely more informative. The Valium /baclofen combo supp Work ok just not as well as Val/lido combo ... for me.

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I've only taken suppositories and they were a waxy type compound and was told they would help more with spasms. I only took a few days as I had daytime spasms and could not function when I used them. I have since had a DRG Stimulator implant (read previous posts). It has offered 50% relief but still not able to sit for long periods of time it did help with spasms. Rocky68

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I am glad you had at least 50% reduction in pain after the DRG. I have tried that, but it did not work for me. I am looking for something that would work for me. I am curious about the Val/lid combo.

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I am at present using Ketamine/lidocaine pessaries for pelvic pain especially in rectum and haven't noticed a big difference yet. You need a prescription from a specialist and it has to be made up at a compounding chemist. I have to pay $105- f0r a 30 day script so its not cheap but if it helps someone it would be worth the cost. Unfortunately the health fund I'm in don't recognise compounding chemists and don't pay anything towards it.

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Tried them not covered by insurance and they never helped. Good luck everyone is different

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