Haven't written in awhile but my pain and symptoms r getting worse!!! My ibs wakes me up every morning with churning of the stomach. Once I get up the pressure in my rectum goes crazy!!!!!! Sometimes I have a bm and other times I have to manually evacuate!!!! Then there is more pressure near the internal anal sphincter and it is excruciating!!!!! I am on five norco a day along with chlorzoxozone and methocarbamol and sometimes that doesn't even touch the pain. Found out I had anismus where my muscles for a bm don't work. Had Botox three months ago and nothing!!!!!! Like I mentioned before have seen five gi, colorectal, nutritionist which destroyed me , acupuncture, dietician, pelvic floor therapist and three shrinks. Going to see a new colorectal and going to have rectal manometry. Also seeing another pelvic floor therapist. I can't take much more between the two. If I take miralax or milk of magnesia my rectum burns like crazy!!!!!!! It hurts so bad!!!! If I wasn't on the norco I wouldn't have constipation but the butt pain is sooo bad I can't get off!!!! Vicious cycle!!!! Have tried every over the counter laxatives and softeners and have been on linzess for three years!!! I also have degenerative disk disease throughout my entire spine. My one doctor thinks my lower back is so messed up after looking at the MRI that it could be affecting my rectal problems. I just have no idea what to do anymore!!!!! I can't live like this!!!! I can't do anything but sit on my heating pad. I have to help my mom as she is 91 but that too is hard considering all the pain I feel. I can't enjoy my grandkids either. I do nothing and hate it!!!!!! The burning and pain is slowly killing me!!!! All of this after working at a very stressful job almost five years ago where I was fired after being off a week with constipation and testing!!!!! This is insane that stress caused all this!!!! Have no idea what to do anymore!!!!!! Depressed and sad!!!! Not a good way to live!!! Mornings r hell as that is when it's the worst!!!! I'm glad I wake up but not to what lies ahead for the day!!!! Found a new gi that seems to care and heard the new colorectal is good too!! We will see. Oh. Tried dr schulzes intestinal formula #1 and it destroyed me!!!!!! Anyway thanks for listening!!!!