I posted Thursday I had blood work after being on Ursodiol for one month. Platelets were 11000, should be above 150000. Was put in the hospital. They took me off the Ursodiol thinking it might be causing it. Yesterday my platelets were up to 55000. They put me back on Ursodiol yesterday and are testing me today and tomorrow to see if platelets go down or continue to improve. I pray that the Ursodiol has not caused this problem. I have had ITPs, where my platelet count has been low before. I think this episode was caused from the streets of my diagnosis of PBC and then having a liver biopsy on July 29. I am 68 years old and have always felt that I was healthy, so was really shocked when I was diagnosed with PBC! This sight has been so helpful to me! It helps to hear of others that have worked through their problems!