Does anyone know why standard blood tests come back >above high reference for Folate? I was very low 4 months ago but the last 2 tests have shown >above high reference 25, yet i have not been supplementing Folate. Levels of Serum B12 have been steadily dropping and the last test was 500 but i was symptomatic of low B12, iron and Vit D so suspect that it wasn't getting to the cells). I have been low in ferritin, deficient in Vit D (I have been supplementing Vit D3, Vit K2, Magnesium Glycinate, Liquid iron and Oral Spray Vit B12,).
If you supplement with B12, how can you tell when you have got levels to a reasonable level? Cannot find how to do this - only that it stays in the system for 4 months so B12 testing will not show accurate measures.
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Furface
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Lots of interesting links, thank you. The hard part is getting a Dr to take it seriously. Most just think its hypochondria. It is far from that. I have adrenal issues also and wonder whether that has anything to do with it.
There is a phenomenon call "folate trapping" in which low cellular methyl B12 causes folate to become blocked in the one carbon folate cycle. The blockage can cause folate levels in the blood to rise despite normal folate intakes.
As suggested in Sleepybunny's links, it would be worth considering active B12, MMA and homocysteine tests. Oral B12 does not work in everyone, particularly those with neurological symptoms. If you have strong neurological symptoms of B12 deficiency, and other causes have been ruled out, it may be worth considering a trial of B12 injections. Vitamin E deficiency can also cause neuropathies.
(I have been supplementing .......Oral Spray Vit B12"
MMA, Homocysteine and Active b12 (holotranscobalamin) test results may be affected by recent B12 supplementation. See link about blood tests in above post.
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