Immunotherapy with Avastin

[GSML]

Good afternoon beautifull ladies.Hope you are all staying strong and enjoying your life.I need your advise please.Did anyone of you had Keytruda immunotherapy with Avastin? My Pet scan shows lymph nodes have cancer and enlarged but I had my previous scan in March and it was clear..Can it be false positive? Started immunotherapy in mid April. Finished last chemo in February. Thank you soo much for all your comments support and advises.God Bless You

[Morini]

Not on the same treatment as you, but I had 2 enlarged lymph nodes in my chest that appeared mid-chemo that turned out to be non-malignant and not an infection. They were described as a 'sarcoid reaction' and have started reducing now. Not sure whether that helps!

[GSML in reply to Morini]

Thank you and how dis you find out that they ate not malignant?? My Pet scan shows activity with Suv 8..

[Morini in reply to GSML]

They biopsied them by Endo-bronchial ultrasound (EBUS). I had to have it done because they wouldn't do my debulking op if they were sinister.

[SUE7777]

I'm on a trial the Prompt Trial for Keytruda only, how did you get Keytruda and Avastin are you in the States and is this a trial?

[Saffery1 in reply to SUE7777]

Hi Sue (im Sue too!). I see from your profile that like me, you've also done carbo/caelyx, and then weekly Taxol. I'm due to start weekly Taxol soon, and am interested to hear how you found it, and more about your Trial? I'm BRCA neg and couldn't tolerate niraparib unfortunately, as it was working... Thanks x

[SUE7777 in reply to Saffery1]

Hi Sue, I found the weekly taxol okay but towards the end my stomach was suffering quite badly. I have been taking pro biopics since I stopped the taxol which have made me feel much better. I’ve been on the prompt trial for a couple months, had a scan on Friday and should find out how it’s going next week. Wasn’t it possible for you to try a different PARP in case the side effects would be easier. Take care Sue xx

[Saffery1 in reply to SUE7777]

Thanks for responding. Because I'm BRCA neg, niraparib was the only one I was allowed to try - I took it in preference to Avastin for maintenance, and then found out Avastin is only approved as maintenance straight after surgery. Although my Onc says Avastin on its own is not very successful. Let me know how your scan goes xx

[SUE7777 in reply to Saffery1]

Will do my CA125 has been holding, I see oncypoos tomorrow xx

[SUE7777 in reply to Saffery1]

Hi Saffery1, the consultation went well the tumour is reduced 5% and everything is stable so that is good news so far. X

[Saffery1 in reply to SUE7777]

That's great, I'm glad to hear it x

[GSML in reply to SUE7777]

Hi dear..Yes I am in States..was denied first..working with 3 oncologist plus my surgeon .I might go for trial ..CA 125 is rising.Pet scan showed activity..Hope you tolerate the treatment good and it is effective.🙏🙏🙏

[SUE7777 in reply to GSML]

Yes Keytruda is not normally prescribed in the UK and it is interesting you got it with Avastin. I had Avastin with front line chemo which worked but not completely. All the best to you. Sue xx

[GSML in reply to SUE7777]

I am Suzanna .Thank You Sue.Its very hard to get it here also..Best of luck to you as well

[SUE7777 in reply to GSML]

Sorry Suzanna. All the best to you too xx

[Leniko]

Avastin has kept me going. I have an infusion every 6 weeks. It has kept my non-operable psoas muscle OVCA (DX in 2014) from enlarging. Minimal side effects. I’m so grateful it keeps my CA125 down.

[GSML in reply to Leniko]

Thank you Leniko and good luck.My ca 125 is increasing .This Tuesday Dr.will decide what to do with therapy