Hi, this is my 1st post. It is surprising how many people are suffering which makes me feel i'm not alone. I am 57yrs old and have had R A since i was 28. Tried everything like you do as you tend to run out of options. Been on a 5 year drugs trial but am currently having 6 monthly infusions of Rituximab for the last 2 years. Under control but still room for improvement.