Update on stopping sulfasalazine : Thought I'd give a... - NRAS


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Update on stopping sulfasalazine

Jaadee profile image
7 Replies

Thought I'd give a quick update. Phoned Rheumy nurse Monday she said to stop sulfasalazine and to have a blood test on Friday which I did to my surprise I got a call from gp yesterday evening asking to go and see him. He has told me my white cell blood count was very low I have been feeling very tired and shivering I put it down to worrying about my mum she has dementia and has broken her hip. I have to have another blood test Monday in the meantime if my temperature goes above 37.5 I have to go straight to hospital has anyone else had this?

7 Replies

Hello you are in the wars

The Sulphasalazine is a DMARD and this can effect the white blood cells, sometimes they will withdraw the Dmard and try another one. The contraindications are textbook I understand , although I am not a GP or specialist. I had this problem about twenty years ago. and the drug was replaced after a time with another one

Hence the blood tests, Your bloods may need some time to recover

Good Luck


Jaadee profile image
Jaadee in reply to

Thank you Bob I will be seeing consultant middle of January stopped leflumonide earlier in the year due to reccuring infections .

Angela123 profile image

Hi Jaadee. Yes, this happened to me last year. I was OK for a few weeks but as I increased the dose I began to feel not well at all. I even passed out twice on the train to work and ended up in A&E. Then after my next routine blood test my Rheumy called to say stop taking it immediately as my white blood cells were very low. I was relieved really as I felt sick and dizzy. I felt much better really quickly, and a week later I had another blood test which showed the white cells bouncing back nicely. Angela.

Jaadee profile image
Jaadee in reply to Angela123

Thanks Angela I have no idea what they will try me on next.

ktk51 profile image

Hi two years a go I was on sulfas and I had a call from my doctor to say stop take in it and to phone my rheumatologist I also had to have my bloods retest she took me off it and I was ok than I am not to go back on it again it can do this same times I was fine my bloods were ok after retest I didn't have to go to hospital if your temp dose go up than do as they say i am not a doctor it is just what happened to me hope this halps all the best

Hi Jaadee

Sorry to hear about your Mum. And your low white count. This happened to me on methotrexate. I was on a high dose so stopped it for a while the restarted on a much lower dose and have been ok since. WCC was so low I was advised not to go out.

Hope things settle down soon.

orchidcass77 profile image

I'm late for bloods couldn't get anything till 13th

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